Patents by Inventor Kathy Griendling

Kathy Griendling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NADPH oxidase inhibitors and uses thereof
    Patent number: 11236053
    Abstract: This disclosure relates to compounds and methods of treating or preventing a Nox related disease or condition comprising administering to a subject in need thereof a Nox inhibitor or pharmaceutical compositions comprising a Nox inhibitor disclosed herein, derivatives, or compounds disclosed herein optionally substituted with one or more substitutes including optional salt and prodrug forms. In certain embodiments, this disclosure relates to sulfonylurea compounds and uses reported herein.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: February 1, 2022
    Assignees: Emory University, Mercer University, Howard University, Union University
    Inventors: Osman Güner, Bernard Lassegue, Kathy Griendling, Qian Xu, David Brown, J. Phillip Bowen, Amol Kulkarni, E. Blake Watkins
  • NADPH Oxidase Inhibitors and Uses Thereof
    Publication number: 20200270214
    Abstract: This disclosure relates to compounds and methods of treating or preventing a Nox related disease or condition comprising administering to a subject in need thereof a Nox inhibitor or pharmaceutical compositions comprising a Nox inhibitor disclosed herein, derivatives, or compounds disclosed herein optionally substituted with one or more substitutes including optional salt and prodrug forms. In certain embodiments, this disclosure relates to sulfonylurea compounds and uses reported herein.
    Type: Application
    Filed: July 26, 2019
    Publication date: August 27, 2020
    Inventors: Osman Güner, Bernard Lassegue, Kathy Griendling, Qian Xu, David Brown, J. Phillip Bowen, Amol Kulkarni, E. Blake Watkins
  • Mitogenic oxygenases
    Publication number: 20060160143
    Abstract: The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.
    Type: Application
    Filed: March 15, 2006
    Publication date: July 20, 2006
    Inventors: J. Lambeth, Kathy Griendling, Bernard Lassegue, Rebecca Arnold, Guangjie Cheng
  • Novel dual oxidases as mitogenic and endocrine regulators
    Publication number: 20050089844
    Abstract: The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates and in peroxidative reactions that affect biological functions including cell division, thyroid hormone biosynthesis and tissue fibrosis. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits (or detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.
    Type: Application
    Filed: May 14, 2001
    Publication date: April 28, 2005
    Inventors: J. Lambeth, Bernard Lassegue, Kathy Griendling, Rebecca Arnold, Guangjie Cheng, Lisa Sharling, Guy Benian, William Edens