Patents by Inventor Kathy Karasiewicz-Mendez

Kathy Karasiewicz-Mendez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLACENTA-DERIVED ADHERENT (PDA) STEM CELL FOR THE TREATMENT OF ADULTS WITH SARS-COV-2 RELATED ACUTE RESPIRATORY FAILURE AND ARDS (COVID-19)
    Publication number: 20230210909
    Abstract: Provided herein are methods of using CD10+, CD34?, CD105+, CD200+ tissue culture plastic-adherent placental cells, e.g. placental stem cells, in the treatment of SARS-CoV-2 related acute respiratory failure and ARDS (COVID-19).
    Type: Application
    Filed: May 10, 2021
    Publication date: July 6, 2023
    Applicant: Celularity Inc.
    Inventors: Robert J. HARIRI, Xiaokui ZHANG, Shuyang HE, Kathy KARASIEWICZ-MENDEZ, Qian YE, Tanel MAHLAKOIV, Stacy HERB, Corey CASPER
  • ENHANCED PLACENTAL STEM CELLS AND USES THEREOF
    Publication number: 20230081199
    Abstract: Provided herein are placental stem cells that exhibit increased survival (“enhanced placental stem cells”), compositions comprising such placental stem cells, and methods of using such placental stem cells and compositions.
    Type: Application
    Filed: October 20, 2022
    Publication date: March 16, 2023
    Applicant: Celularity Inc.
    Inventors: Stewart ABBOT, Kathy KARASIEWICZ-MENDEZ, Robert J. HARIRI, Xiaokui ZHANG
  • PLACENTA-DERIVED ADHERENT CELL EXOSOMES AND USES THEREOF
    Publication number: 20220241347
    Abstract: Provided herein are compositions of placenta-derived adherent cell exosomes and methods of making and using the same. In one aspect, provided herein are compositions comprising exosomes produced by and/or derived from placental cells, e.g., placenta-derived adherent cells. In certain embodiments, the exosomes provided herein are produced by placenta-derived adherent cells that have been cultured in vitro for, e.g., 1, 2, 3, 4, 5, 6 or more passages.
    Type: Application
    Filed: October 7, 2021
    Publication date: August 4, 2022
    Applicant: Celularity Inc.
    Inventors: Eric Law, Andrew Morschauser, Aleksander Francki, Jennifer Paredes, Kathy Karasiewicz-Mendez, Allan Reduta, Vladimir Jankovic, Ivana Djuretic, Robert J. Hariri
  • PLACENTA-DERIVED ALLOGENEIC CAR-T CELLS AND USES THEREOF
    Publication number: 20220118014
    Abstract: The present invention discloses populations of T cells expressing a chimeric antigen receptor (CAR), wherein said T cells are placental T cells derived from cord blood, placental perfusate, or a mixture thereof. Such populations of cells are shown to be improved in a number of aspects over alternative populations of cells such as those derived from peripheral blood mononuclear cell T cells. It also discloses methods of treating cancer, such as a hematologic cancer, e.g., a B cell cancer, or a symptom thereof in a patient in need thereof. These methods comprise administering to the patient an amount of the population of T cells of any one of the invention effective to alleviate the cancer or symptom thereof in the patient.
    Type: Application
    Filed: December 2, 2019
    Publication date: April 21, 2022
    Applicant: Celularity Inc.
    Inventors: Robert J. HARIRI, Kathy KARASIEWICZ-MENDEZ, Tianjian LI
  • Placenta-derived adherent cell exosomes and uses thereof
    Patent number: 11173182
    Abstract: Provided herein are compositions of placenta-derived adherent cell exosomes and methods of making and using the same. In one aspect, provided herein are compositions comprising exosomes produced by and/or derived from placental cells, e.g., placenta-derived adherent cells. In certain embodiments, the exosomes provided herein are produced by placenta-derived adherent cells that have been cultured in vitro for, e.g., 1, 2, 3, 4, 5, 6 or more passages.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: November 16, 2021
    Assignee: Celularity Inc.
    Inventors: Eric Law, Andrew Morschauser, Aleksander Francki, Jennifer Paredes, Kathy Karasiewicz-Mendez, Allan Reduta, Vladimir Jankovic, Ivana Djuretic, Robert J. Hariri
  • ENHANCED PLACENTAL STEM CELLS AND USES THEREOF
    Publication number: 20210238544
    Abstract: Provided herein are placental stem cells that exhibit increased survival (“enhanced placental stem cells”), compositions comprising such placental stem cells, and methods of using such placental stem cells and compositions.
    Type: Application
    Filed: April 15, 2019
    Publication date: August 5, 2021
    Applicant: CELULARITY, INC.
    Inventors: Stewart Abbot, Kathy Karasiewicz-Mendez, Xiaokui Zhang
  • Enhanced placental stem cells and uses thereof
    Patent number: 10329529
    Abstract: Provided herein are placental stem cells that exhibit increased survival (“enhanced placental stem cells”), compositions comprising such placental stem cells, and methods of using such placental stem cells and compositions.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 25, 2019
    Assignee: CELULARITY, INC.
    Inventors: Stewart Abbot, Kathy Karasiewicz-Mendez, Xiaokui Zhang
  • ENHANCED PLACENTAL STEM CELLS AND USES THEREOF
    Publication number: 20160017282
    Abstract: Provided herein are placental stem cells that exhibit increased survival (“enhanced placental stem cells”), compositions comprising such placental stem cells, and methods of using such placental stem cells and compositions.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 21, 2016
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Stewart Abbot, Kathy Karasiewicz-Mendez, Xiaokui Zhang