Abstract: A dressing for treating a wound on a digit includes a digit contact layer configured to substantially prevent adherence of the dressing to the wound and an antimicrobial layer coupled to a wound-facing side of the digit contact layer. The antimicrobial layer includes an antimicrobial substance. A first roll is coupled to a non-wound-facing side of the digit contact layer and unrollable to cover the digit, the digit contact layer, and the antimicrobial layer and a second roll is coupled to the first roll and unrollable to cover the first roll, the digit, the digit contact layer, and the antimicrobial layer.

Abstract: An example method for facilitating milk extraction from a breast can include: activating a breast pump system to administer multiple breast pumping cycles, each breast pumping cycle comprising an increasing vacuum segment during which an amount of vacuum force applied to a breast increases; and applying vibrations to the breast during at least a portion of each of the breast pumping cycles using a vibration device, wherein the vibrations are applied in a segmented pattern comprising discrete pressure intervals during the increasing vacuum segment, wherein the segmented pattern pauses at intermediate pressure plateaus between atmospheric pressure and a target vacuum level.

Abstract: A medical delivery device for treating a tunneling wound includes an outer sleeve, a plunger, and a hollow tube extending through an opening in the plunger. The plunger is configured to deliver a wound treatment material from an inner cavity of the outer sleeve, through a cavity opening on the outer sleeve, and into the tunneling wound. The hollow tube is configured to deliver a fluid to the wound treatment material after insertion into the tunneling wound. In some embodiments, the medical delivery device may further include a flap disposed on the outer sleeve. The flap may be reconfigurable between a closed position in which the flap is configured to shield the cavity opening, and an open position in which the flap is configured to allow the wound treatment material to be ejected through the cavity opening.

Abstract: A dressing (as well as uses, systems, and methods including such dressing) is provided that includes a contact layer with a first surface configured to contact a tissue site in a subject and includes a scaffold configured to structurally support the contact layer, where the contact layer includes a bioresorbable material. The dressing may advantageously exhibit protease-modulating activity under physiological conditions.

Abstract: The present technology generally relates to a biomaterial that includes a thiolated biopolymer and one or more agents that include growth factors, peptides, or combinations thereof, where the one or more agents are conjugated to the thiolated biopolymer. Also disclosed herein are wound dressings that include the biomaterial of the present technology, methods of treating a wound upon application of the wound dressing, and kits including the wound dressing and instructions for use.

Abstract: A dressing that includes an absorbent, antimicrobial layer and a bioresorbable layer is disclosed herein. The absorbent, antimicrobial layer may be formed from nonwoven fibers. The bioresorbable layer may include an extracellular polymeric substance-active agent, such as citric acid. At least a portion of the nonwoven fibers may include carboxymethylcellulose fibers and alginate fibers.

Abstract: A dressing for treating a wound on a digit includes a digit contact layer configured to substantially prevent adherence of the dressing to the wound and an antimicrobial layer coupled to a wound-facing side of the digit contact layer. The antimicrobial layer includes an antimicrobial substance. A first roll is coupled to a non-wound-facing side of the digit contact layer and unrollable to cover the digit, the digit contact layer, and the antimicrobial layer and a second roll is coupled to the first roll and unrollable to cover the first roll, the digit, the digit contact layer, and the antimicrobial layer.

Abstract: The technology described in this application provides a dressing (as well as uses, systems, and methods including such dressing) that includes a contact layer with a first surface configured to contact a tissue site in a subject and includes a scaffold configured to structurally support the contact layer, where the contact layer includes a bioresorbable material. The dressing may advantageously exhibit protease-modulating activity under physiological conditions.

Abstract: A medical delivery device for treating a tunneling wound includes an outer sleeve, a plunger, and a hollow tube extending through an opening in the plunger. The plunger is configured to deliver a wound treatment material from an inner cavity of the outer sleeve, through a cavity opening on the outer sleeve, and into the tunneling wound. The hollow tube is configured to deliver a fluid to the wound treatment material after insertion into the tunneling wound. In some embodiments, the medical delivery device may further include a flap disposed on the outer sleeve. The flap may be reconfigurable between a closed position in which the flap is configured to shield the cavity opening, and an open position in which the flap is configured to allow the wound treatment material to be ejected through the cavity opening.

Abstract: A composition comprising an oxidoreductase enzyme and a substrate for the enzyme for use in treating or preventing biofilm formation by a population of pathogenic bacteria. The composition can be incorporated into a wound dressing for use in promoting wound healing.

Abstract: A biomaterial that includes collagen and an antimicrobial agent such as citric acid is provided herein. The biomaterial may further include a metal, such as silver, and an anionic polysaccharide, such as oxidized regenerated cellulose (ORC). Methods of using the biomaterial in wound therapy and on medical implants, and methods for preparing the biomaterial are also disclosed herein.

Abstract: A composition comprising an oxidoreductase enzyme and a substrate for the enzyme for use in treating or preventing biofilm formation by a population of pathogenic bacteria. The composition can be incorporated into a wound dressing for use in promoting wound healing.