Patents by Inventor Katie Stiles

Katie Stiles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetic modification of the AAV capsid resulting in altered tropism and enhanced vector delivery
    Patent number: 11821009
    Abstract: Modified AAV vectors and uses thereof are provided.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: November 21, 2023
    Assignee: Cornell University
    Inventors: Ronald G. Crystal, Katie Stiles
  • GENE THERAPY FOR EOSINOPHILIC DISORDERS
    Publication number: 20200330608
    Abstract: Compositions and methods for eosinophilia in a mammal are provided. In one embodiment, the composition is a viral gene therapy vector, and a single dose of the vector reduces increased lumbers of eosinophils in a mammal.
    Type: Application
    Filed: December 28, 2018
    Publication date: October 22, 2020
    Inventors: Ronald G. Crystal, Odeiya E. Pagovich, Katie Stiles
  • OXIDATION-RESISTANT AAT GENE THERAPY
    Publication number: 20200102575
    Abstract: A gene therapy treatment for alpha 1-antitrypsin (AAT) deficiency is provided comprising a plasmid or viral, e.g., an AAV, vector coding for an elastase- or cathepsin G-inhibiting, oxidation-resistant human AAT with a substitution at, for example, Met358 and/or Met351.
    Type: Application
    Filed: March 29, 2018
    Publication date: April 2, 2020
    Inventors: Ronald G. Crystal, Katie Stiles, Meredith Sosulski, Stephen M. Kaminsky, Dolan Sondhi, Bishnu De, Jonathan Rosenberg
  • GENETIC MODIFICATION OF THE AAV CAPSID RESULTING IN ALTERED TROPISM AND ENHANCED VECTOR DELIVERY
    Publication number: 20200032220
    Abstract: Modified AAV vectors and uses thereof are provided.
    Type: Application
    Filed: May 14, 2019
    Publication date: January 30, 2020
    Inventors: Ronald G. Crystal, Katie Stiles