Patents by Inventor Katiuscia Arrighi

Katiuscia Arrighi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of gabapentin
    Patent number: 7759517
    Abstract: The present invention relates to a process for the preparation of gabapentin and, more in particular, to a method of synthesis of 1,1-cyclohexane acetic acid monoamide, an intermediate used in the preparation of gabapentin, comprising the basic hydrolysis reaction of ?, -diaminocarbonyl-?,?-pentamethylene glutarimide.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: July 20, 2010
    Assignee: Zach System S.P.A.
    Inventors: Marco Villa, Maurizio Paiocchi, Katiuscia Arrighi, Francesco Corcella, Vincenzo Cannata, Giorgio Soriato, Massimo Verzini
  • PROCESS FOR THE PREPARATION OF GABAPENTIN
    Publication number: 20090326266
    Abstract: A process for the preparation of 1,1-cyclohexanediacetic acid monoamide comprising the amination of 1,1-cyclohexanediacetic acid anhydride by reaction with aqueous NH3 at a temperature lower than 30° C. by using a NH3/anhydride molar ratio lower than 3, and the product precipitation through the acidification of the reaction mixture; a precipitation process of 1,1-cyclohexanediacetic acid monoamide; and a process for the synthesis of gabapentin comprising the above preparation of 1,1-cyclohexanediacetic acid monoamide, the Hofmann transposition of the same monoamide, the purification of a gabapentin salt and the crystallization from organic solvent.
    Type: Application
    Filed: March 9, 2009
    Publication date: December 31, 2009
    Applicant: ZACH SYSTEM S.p.A.
    Inventors: Katiuscia ARRIGHI, Vincenzo CANNATA, Francesco CORCELLA, Gaetano MARCHIORO, Andrea NICOLI, Maurizio PAIOCCHI, Marco VILLA
  • Process for the Preparation of Gabapentin
    Publication number: 20080097122
    Abstract: The present invention relates to a process for the preparation of gabapentin and, more in particular, to a method of synthesis of 1,1-cyclohexane acetic acid monoamide, an intermediate used in the preparation of gabapentin, comprising the basic hydrolysis reaction of ?,?-diaminocarbonyl-?,?-pentamethylene glutarimide.
    Type: Application
    Filed: June 22, 2005
    Publication date: April 24, 2008
    Applicant: AAMBON GROUPS P.P.A.
    Inventors: Marco Villa, Maurizio Paiocchi, Katiuscia Arrighi, Francesco Corcella, Vincenzo Cannata, Giorgio Soriato, Massimo Verzini
  • Process for the preparation of gabapentin
    Publication number: 20070066843
    Abstract: The present invention relates to an improved process for the preparation of gabapentin and, more particularly, to an improvement of the preparation reaction of 1,1-cyclohexanediacetic acid monoamide, intermediate utilized in the preparation of gabapentin.
    Type: Application
    Filed: November 9, 2004
    Publication date: March 22, 2007
    Inventors: Katiuscia Arrighi, Vincenzo Cannata, Francesco Corcella, Gaetano Marchioro, Andrea Nicoli, Maurizio Paiocchi, Marco Villa
  • Process for the preparation of heteroaryl-phenylalanines
    Patent number: 6448408
    Abstract: A process for the preparation of heteroaryl-phenylalanines of formula (II) in which R is a hydrogen atom, a straight or branched C1-C4 alkyl groups or a benzyl group; R1 is an optionally substituted 5 or 6 membered aromatic heterocyclic group with one or two heteroatoms selected among nitrogen, oxygen and sulphur; comprising a cross-coupling reaction among heteroaryl-zinc halide and phenylalanine derivatives is described. Compounds of formula (II) are intermediates useful for the preparation of compounds endowed with pharmacological activity.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: September 10, 2002
    Assignee: Zambon Group S.p.A.
    Inventors: Marco Villa, Maurizio Paiocchi, Katiuscia Arrighi
  • PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES
    Publication number: 20020028946
    Abstract: 1
    Type: Application
    Filed: June 21, 1999
    Publication date: March 7, 2002
    Inventors: MARCO VILLA, MAURIZIO PAIOCCHI, KATIUSCIA ARRIGHI
  • Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
    Patent number: 6271375
    Abstract: A process of direct metalation of phenyltetrazoles useful for preparing compounds of formula (II) intermediates for the synthesis of angiotensin II antagonists is described.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: August 7, 2001
    Assignee: Zambon Group S.p.A.
    Inventors: Marco Villa, Pietro Allegrini, Katiuscia Arrighi, Maurizio Paiocchi