Patents by Inventor Katja Fiedler

Katja Fiedler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220396796
    Abstract: The present invention relates to RNA, particularly an immunostimulatory RNA (isRNA), a coding RNA or a combination thereof, for use in the treatment or prophylaxis of a disease, in particular a tumor and/or cancer disease. The present invention also provides pharmaceutical compositions, and a kit comprising the RNA(s). Further, the invention also comprises medical uses of the RNA(s) and compositions comprising the RNA(s).
    Type: Application
    Filed: January 10, 2022
    Publication date: December 15, 2022
    Applicant: CureVac AG
    Inventors: Mariola FOTIN-MLECZEK, Aleksandra KOWALCZYK, Regina HEIDENREICH, Ulrike GNAD-VOGT, Ute KLINKHARDT, Katja FIEDLER
  • Publication number: 20220340641
    Abstract: The present invention provides an mRNA molecule encoding at least one KRAS variant peptide. Further, the invention provides a pharmaceutical composition and kit comprising the mRNA molecule. The mRNA molecule, pharmaceutical composition and kit are useful for treating cancer.
    Type: Application
    Filed: December 6, 2019
    Publication date: October 27, 2022
    Applicant: CureVac AG
    Inventors: Amit AGGARWAL, Katja FIEDLER, Ulrike GNAD-VOGT, Regina HEIDENREICH, Mythili KONERU, Gregory D. PLOWMAN
  • Publication number: 20210198649
    Abstract: The present invention provides novel artificial nucleic acid molecules encoding at least one antigenic peptide or protein and at least one additional sequence preferably targeting the antigenic peptides or proteins to cellular compartments of interest. Further, the invention provides (pharmaceutical) compositions or vaccines and kits comprising said nucleic acid molecules. The nucleic acid molecules, (pharmaceutical) compositions or vaccines and kits are useful for treating a variety of diseases such as cancer, infectious diseases, autoimmune diseases, allergies or graft-versus host disease.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 1, 2021
    Applicant: CureVac AG
    Inventors: Mariola FOTIN-MLECZEK, Katja FIEDLER, Aleksandra KOWALCZYK, Regina HEIDENREICH
  • Patent number: 10988754
    Abstract: The present invention provides novel artificial nucleic acid molecules encoding at least one antigenic peptide or protein and at least one additional sequence preferably targeting the antigenic peptides or proteins to cellular compartments of interest. Further, the invention provides (pharmaceutical) compositions or vaccines and kits comprising said nucleic acid molecules. The nucleic acid molecules, (pharmaceutical) compositions or vaccines and kits are useful for treating a variety of diseases such as cancer, infectious diseases, autoimmune diseases, allergies or graft-versus host disease.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: April 27, 2021
    Assignee: Cure Vac AG
    Inventors: Mariola Fotin-Mleczek, Katja Fiedler, Aleksandra Kowalczyk, Regina Heidenreich
  • Publication number: 20200085944
    Abstract: The present invention relates to the field of biomedicine, and in particular to the field of therapeutic nucleic acids. The present invention provides a combination of an RNA encoding an epitope and immune checkpoint inhibitors. A pharmaceutical composition, vaccine, and kit-of-parts comprising said combination are also provided. Furthermore, the present invention relates to the combination, (pharmaceutical) composition, vaccine or kit-of-parts for use in medicine, and in particular in the treatment and/or prophylaxis of cancer, infectious diseases and other diseases and disorders.
    Type: Application
    Filed: March 16, 2018
    Publication date: March 19, 2020
    Inventors: Regina HEIDENREICH, Katja FIEDLER, Mariola FOTIN-MLECZEK, Aleksandra KOWALCZYK, Knut ELBERS, Melanie WURM
  • Publication number: 20190185859
    Abstract: The present invention relates to RNA, particularly an immunostimulatory RNA (isRNA), a coding RNA or a combination thereof, for use in the treatment or prophylaxis of a disease, in particular a tumor and/or cancer disease. The present invention also provides pharmaceutical compositions, and a kit comprising the RNA(s). Further, the invention also comprises medical uses of the RNA(s) and compositions comprising the RNA(s).
    Type: Application
    Filed: August 14, 2017
    Publication date: June 20, 2019
    Inventors: Mariola FOTIN-MLECZEK, Aleksandra KOWALCZYK, Regina HEIDENREICH, Ulrike GNAD-VOGT, Ute KLINKHARDT, Katja FIEDLER
  • Publication number: 20190040378
    Abstract: The present invention provides novel artificial nucleic acid molecules encoding at least one antigenic peptide or protein and at least one additional sequence preferably targeting the antigenic peptides or proteins to cellular compartments of interest. Further, the invention provides (pharmaceutical) compositions or vaccines and kits comprising said nucleic acid molecules. The nucleic acid molecules, (pharmaceutical) compositions or vaccines and kits are useful for treating a variety of diseases such as cancer, infectious diseases, autoimmune diseases, allergies or graft-versus host disease.
    Type: Application
    Filed: July 3, 2018
    Publication date: February 7, 2019
    Inventors: Mariola Fotin-Mleczek, Katja Fiedler, Aleksandra Kowalczyk, Regina Heidenreich