Patents by Inventor Katleen Fierens

Katleen Fierens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TAU PET IMAGING LIGANDS
    Publication number: 20220024896
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: October 7, 2021
    Publication date: January 27, 2022
    Inventors: José Ignacio Andrés-Gil, Guy Maurits R. Bormans, Lieven Denis Herwig Declercq, Katleen Fierens, Joseph Elisabeth Leenaerts, Diederik Willem Elisabeth Moechars, Frederik Jan Rita Rombouts, Hartmuth Kolb, Wei Zhang
  • Tau PET imaging ligands
    Patent number: 11168068
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: November 9, 2021
    Assignee: Janssen Pharmaceutica NV
    Inventors: José Ignacio Andrés-Gil, Guy Maurits R. Bormans, Lieven Denis Herwig Declercq, Katleen Fierens, Joseph Elisabeth Leenaerts, Diederik Willem Elisabeth Moechars, Frederik Jan Rita Rombouts, Hartmuth Kolb, Wei Zhang
  • TAU PET IMAGING LIGANDS
    Publication number: 20210283277
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: April 30, 2021
    Publication date: September 16, 2021
    Inventors: Diederik Willem Elisabeth MOECHARS, Frederik Jan Rita ROMBOUTS, Joseph Elisabeth LEENAERTS, José Ignacio ANDRéS-GIL, Katleen FIERENS, Vladimir CHUPAKHIN, Guy Mauritis R. BORMANS, Lieven Denis Herwig DECLERCQ, Hartmuth KOLB, Wei ZHANG
  • TAU PET IMAGING LIGANDS
    Publication number: 20190284165
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: July 14, 2017
    Publication date: September 19, 2019
    Inventors: Jos ANDRéS-GIL Andres-Gil, Guy Maurits R. BORMANS, Lieven Denis Herwig DECLERCQ, Katleen FIERENS, Joseph Elisabeth LEENAERTS, Diederik Willem Elisabeth MOECHARS, Frederik Jan Rita ROMBOUTS, Hartmuth KOLB, Wei ZHANG
  • TAU PET IMAGING LIGANDS
    Publication number: 20190038784
    Abstract: The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
    Type: Application
    Filed: February 1, 2017
    Publication date: February 7, 2019
    Inventors: Diederik Willem Elisabeth MOECHARS, Frederik Jan Rita ROMBOUTS, Joseph Elisabeth LEENAERTS, José Ignacio ANDRéS-GIL, Katleen FIERENS, Vladimir CHUPAKHIN, Guy Maurits R. BORMANS, Lieven Denis Herwig DECLERCQ, Hartmuth KOLB, Wei ZHANG
  • Biocatalyst inhibitors
    Patent number: 6936703
    Abstract: The present invention concerns a method for the separation and/or isolation of inhibitors of cellulolytic, xylanolytic and/or beta-glucanolytic enzymes, inhibitors obtainable by said method, and process for obtaining micro-organism, plant or plant material wherein the activity of the inhibitor according to the invention is increased or reduced and to the use of the inhibitor, using the cited micro-organism, plant or plant material and/or the use of endoxylanases selected or modified using these inhibitors in a variety of process and applications.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: August 30, 2005
    Assignee: K.U. Leuven Research and Development
    Inventors: Jan Delcour, Winok Debyser, Kurt Gebruers, Hans Goesaert, Katleen Fierens, Johan Robben, Steven Van Campenhout
  • Biocatalyst inhibitors
    Publication number: 20030195151
    Abstract: The present invention concerns a method for the separation and/or isolation of inhibitors of cellulolytic, xylanolytic and/or beta-glucanolytic enzymes, inhibitors obtainable by said method, and process for obtaining micro-organism, plant or plant material wherein the activity of the inhibitor according to the invention is increased or reduced and to the use of the inhibitor, using the cited micro-organism, plant or plant material and/or the use of endoxylanases selected or modified using these inhibitors in a variety of process and applications.
    Type: Application
    Filed: December 23, 2002
    Publication date: October 16, 2003
    Inventors: Jan Delcour, Winok Debyser, Kurt Gebruers, Hans Goesaert, Katleen Fierens, Johan Robben, Steven Van Campenhout