Patents by Inventor Katrien Berns

Katrien Berns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR PREDICTING RESISTANCE TO ANTICANCER TREATMENT
    Publication number: 20140287931
    Abstract: The instant application provides methods and related compositions pertaining to the identification of resistance to anticancer treatment in. a patient. In a particular embodiment, the invention provides biomarkers for the identification of resistance to anticancer treatment in a breast cancer patient, wherein a reduced expression of a MEDIATOR and/or SWI/SNF complex gene in the breast cancer cells of the patient indicates that the breast cancer cells in the patient may be successfully treated with a PI3K and/or mTOR inhibitor.
    Type: Application
    Filed: April 4, 2012
    Publication date: September 25, 2014
    Applicant: Stichting het Nederlands Kanker Instituut - Antoni van Leeuwenhoek ziekenhuis
    Inventors: Rene Bernards, Sidong Huang, Michael Holzel, Katrien Berns
  • Involvement of Lipid Kinase, and Signal Transduction Pathway Comprising Said Lipid Kinase, in Resistance to HER2-Targeting Therapy
    Publication number: 20100297624
    Abstract: The invention is related to a method for determining whether an individual suffering from cancer is at risk of exhibiting or acquiring a reduced response towards HER2-targeting therapy. In one aspect, the invention utilizes the activity of a signal transduction pathway modulated by a lipid kinase for determining said risk.
    Type: Application
    Filed: April 14, 2008
    Publication date: November 25, 2010
    Applicant: STICHTING HET NEDERLANDS KANKER INSTITUUT
    Inventors: Katrien Berns, Rene Bernards