Patents by Inventor Katrien Claes

Katrien Claes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOOLS AND METHODS FOR EXPRESSION OF MEMBRANE PROTEINS
    Publication number: 20230071321
    Abstract: The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
    Type: Application
    Filed: October 24, 2022
    Publication date: March 9, 2023
    Inventors: Jan Steyaert, Nico L.M. Callewaert, Toon Laeremans, Els Pardon, Kristof Vandewalle, Katrien Claes
  • Tools and methods for expression of membrane proteins
    Patent number: 11479791
    Abstract: The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: October 25, 2022
    Inventors: Jan Steyaert, Nico L. M. Callewaert, Toon Laeremans, Els Pardon, Kristof Vandewalle, Katrien Claes
  • HOST CELL FOR PRODUCING A PROTEIN OF INTEREST
    Publication number: 20200399325
    Abstract: A eukaryotic host cell engineered to produce a heterologous protein of interest (POI), which cell is genetically modified to reduce production of at least one of three different endogenous host cell protein (HCP), and its use in a method of producing the POI.
    Type: Application
    Filed: January 30, 2019
    Publication date: December 24, 2020
    Inventors: Katrien CLAES, James GRAHAM, Sylwia JOZWIAK, Christoph KIZIAK
  • TOOLS AND METHODS FOR EXPRESSION OF MEMBRANE PROTEINS
    Publication number: 20180237530
    Abstract: The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
    Type: Application
    Filed: February 12, 2018
    Publication date: August 23, 2018
    Inventors: Jan Steyaert, Nico L.M. Callewaert, Toon Laeremans, Els Pardon, Kristof Vandewalle, Katrien Claes
  • Tools and methods for expression of membrane proteins
    Patent number: 9890217
    Abstract: The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
    Type: Grant
    Filed: January 21, 2013
    Date of Patent: February 13, 2018
    Assignees: VIB VZW, VRIJE UNIVERSITEIT BRUSSEL, UNIVERSITEIT GENT
    Inventors: Jan Steyaert, Nico Callewaert, Toon Laeremans, Els Pardon, Kristof Vandewalle, Katrien Claes
  • TOOLS AND METHODS FOR EXPRESSION OF MEMBRANE PROTEINS
    Publication number: 20140357521
    Abstract: The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
    Type: Application
    Filed: January 21, 2013
    Publication date: December 4, 2014
    Inventors: Jan Steyaert, Nico Callewaert, Toon Laeremans, Els Pardon, Kristof Vandewalle, Katrien Claes