Patents by Inventor Katrin Lorenz

Katrin Lorenz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8772492
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: July 8, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, Jochen Goerlitzer, Matthias Lohn
  • Cycloalkylamine substituted isoquinolone derivatives
    Patent number: 8742116
    Abstract: The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: June 3, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Armin Hofmeister, Katrin Lorenz, Joachim Brendel, Matthias Löhn, John Weston
  • Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8710077
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: April 29, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, Jochen Goerlitzer, Matthias Löhn, Sandrine Biscarrat, Fréderic Jeannot, Olivier Duclos
  • Substituted isoquinolines and isoquinolinones as Rho kinase inhibitors
    Patent number: 8541449
    Abstract: The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: September 24, 2013
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, John Weston, Matthias Loehn, Heinz-Werner Kleemann, Olivier Duclos, Frederic Jeannot
  • Bi- and polycyclic substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8524737
    Abstract: The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: September 3, 2013
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, Matthias Loehn, Olivier Duclos, Sandrine Biscarrat
  • 6-Substituted isoquinolines and isoquinolinones
    Publication number: 20130109715
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) t,21 useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: December 14, 2012
    Publication date: May 2, 2013
    Applicant: SANOFI
    Inventors: Oliver PLETTENBURG, Katrin LORENZ, Matthias LOEHN, John WESTON, Heinz-Werner KLEEMANN
  • 6-substituted isoquinolines and isoquinolinones
    Patent number: 8399482
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 19, 2013
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, Matthias Loehn, John Weston, Heinz-Werner Kleemann
  • BI- AND POLYCYCLIC SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES
    Publication number: 20110190340
    Abstract: The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: August 4, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver Plettenburg, Katrin Lorenz, Matthias Loehn, Olivier Duclos, Sandrine Biscarrat
  • 6-SUBSTITUTED ISOQUINOLINES AND ISOQUINOLINONES
    Publication number: 20110190339
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: December 16, 2010
    Publication date: August 4, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Katrin LORENZ, Matthias LOEHN, John WESTON, Heinz-Werner KLEEMANN
  • SUBSTITUTED ISOQUINOLINES AND ISOQUINOLINONES AS RHO KINASE INHIBITORS
    Publication number: 20110190341
    Abstract: The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 19, 2009
    Publication date: August 4, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver Plettenburg, Katrin Lorenz, John Weston, Matthias Loehn, Heinz-Werner Kleemann, Olivier Duclos, Frederic Jeannot
  • New substituted isoquinoline and isoquinolinone derivatives
    Publication number: 20100056566
    Abstract: The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: Sanofi-aventis
    Inventors: Oliver PLETTENBURG, Katrin LORENZ, Jochen GOERLITZER, Matthias Löhn
  • CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLONE DERIVATIVES
    Publication number: 20100056518
    Abstract: The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Armin HOFMEISTER, Katrin LORENZ, Joachim BRENDEL, Matthias Löhn, John Weston
  • Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
    Publication number: 20100056553
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Katrin LORENZ, Jochen GOERLITZER, Matthias Löhn, Sandrine BISCARRAT, Fréderic JEANNOT, Olivier DUCLOS