Patents by Inventor Katrin Mackarehtschian

Katrin Mackarehtschian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug rescue by redesign of ADMET/PK properties
    Publication number: 20030073069
    Abstract: Otherwise efficacious drugs having an ADMET/PK (absorption, distribution, metabolism, elimination, toxicity, i.e., pharmacokinetic) problem are redesigned or “rescued” by applying computational techniques that identify related chemical structures that preserve the initial drug's effectiveness but improve its ADMET/PK properties. The otherwise efficacious drug may be subjected to a suite of computational tools that identify sites responsible for problematic ADMET/PK properties and/or identify related compounds that have improved ADMET/PK properties.
    Type: Application
    Filed: October 15, 2001
    Publication date: April 17, 2003
    Inventors: Harold E. Selick, Kenneth R. Korzekwa, Katrin Mackarehtschian