Patents by Inventor Katrina M. Miranda

Katrina M. Miranda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer
    Patent number: 10213445
    Abstract: The present disclosure provides methods utilizing the diazeniumdiolate-based prodrugs for the treatment of cancer via various mechanisms and procedures. The disclosure also provides kits comprising the diazeniumdiolate-based prodrugs.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: February 26, 2019
    Assignees: Arizona Board of Regents on Behalf of the University of Arizona, a body corporate, The United States of America as Represented by the Secretary of the Department of Health and Human Services
    Inventors: Katrina M. Miranda, David A. Wink, Debashree Basudhar
  • Compositions and Methods of Diazeniumdiolate-based Prodrugs for Treating Cancer
    Publication number: 20170333456
    Abstract: The present disclosure provides methods utilizing the diazeniumdiolate-based prodrugs for the treatment of cancer via various mechanisms and procedures. The disclosure also provides kits comprising the diazeniumdiolate-based prodrugs.
    Type: Application
    Filed: November 6, 2015
    Publication date: November 23, 2017
    Applicants: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSI TY OF ARIZONA, The United States of America as Represented by the Secretary of the Department of Health and Human S
    Inventors: Katrina M. Miranda, David A. Wink, Debashree Basudhar
  • Nitroxyl (HNO) releasing compounds and uses thereof in treating diseases
    Patent number: 8633177
    Abstract: Disclosed is a compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) in which R1, R2, R3, and R4 are defined herein and pharmaceutical compositions thereof. Further provided is a method of treating various disorders, such as a disorder selected from the group consisting of a cardiovascular disorder, cancer, chronic pain, alcohol dependence, and inflammation in a patient comprising administering an effective amount of a compound or pharmaceutically acceptable salt of formula (I).
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: January 21, 2014
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The Arizona Board of Regents, on behalf of the University of Arizona
    Inventors: Katrina M. Miranda, David A. Wink, Debra J. Salmon, Debashree Basudhar, Larry K. Keefer, Joseph E. Saavedra, Daniela Andrei
  • NITROXYL (HNO) RELEASING COMPOUNDS AND USES THEREOF IN TREATING DISEASES
    Publication number: 20130065863
    Abstract: Disclosed is a compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) in which R1, R2, R3, and R4 are defined herein and pharmaceutical compositions thereof. Further provided is a method of treating various disorders, such as a disorder selected from the group consisting of a cardiovascular disorder, cancer, chronic pain, alcohol dependence, and inflammation in a patient comprising administering an effective amount of a compound or pharmaceutically acceptable salt of formula (I).
    Type: Application
    Filed: March 18, 2011
    Publication date: March 14, 2013
    Applicants: The Arizona Board of Regents, on behalf of the University of Arizona, Office of Technology Transfer, NIH
    Inventors: Katrina M. Miranda, David A. Wink, Debra J. Salmon, Debashree Basudhar, Larry K. Keefer, Joseph E. Saavedra, Daniela Andrei
  • Method of treating ischemia/reperfusion injury with nitroxyl donors
    Patent number: 8268890
    Abstract: Nitroxyl donating compounds are administered prior to the onset of ischemia for the prevention and/or reduction of ischemia/reperfusion injury in subjects at risk for ischemia. Nitroxyl donors also are administered to organs to be transplanted for the prevention and/or reduction of ischemia/reperfusion injury upon reperfusion in a recipient. Nitroxyl donors include any nitroxyl donating compound. In particular cases the nitroxyl donor is a nitroxyl-donating diazeniumdiolate, such as Angeli's salt or IPA/NO.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: September 18, 2012
    Assignees: Johns Hopkins University, The United States of America as represented by the Secretary of Health and Human Services, The Regents of the University of California
    Inventors: David A. Wink, Martin Feelisch, Pasquale Pagliaro, David A. Kass, Nazareno Paolocci, Katrina M. Miranda, Jon M. Fukuto
  • METHOD OF TREATING ISCHEMIA/REPERFUSION INJURY WITH NITROXYL DONORS
    Publication number: 20090246296
    Abstract: Nitroxyl donating compounds are administered prior to the onset of ischemia for the prevention and/or reduction of ischemia/reperfusion injury in subjects at risk for ischemia. Nitroxyl donors also are administered to organs to be transplanted for the prevention and/or reduction of ischemia/reperfusion injury upon reperfusion in a recipient. Nitroxyl donors include any nitroxyl donating compound. In particular cases the nitroxyl donor is a nitroxyl-donating diazeniumdiolate, such as Angeli's salt or IPA/NO.
    Type: Application
    Filed: December 30, 2008
    Publication date: October 1, 2009
    Inventors: David A. Wink, Martin Feelisch, Pasquale Pagliaro, David A. Kass, Nazareno Paolocci, Katrina M. Miranda, Jon M. Fukuto
  • Method of treating ischemia/reperfusion injury with nitroxyl donors
    Publication number: 20040038947
    Abstract: Nitroxyl donating compounds are administered prior to the onset of ischemia for the prevention and/or reduction of ischemia/reperfusion injury in subjects at risk for ischemia. Nitroxyl donors also are administered to organs to be transplanted for the prevention and/or reduction of ischemia/reperfusion injury upon reperfusion in a recipient. Nitroxyl donors include any nitroxyl donating compound. In particular cases the nitroxyl donor is a nitroxyl-donating diazeniumdiolate, such as Angeli's salt or IPA/NO.
    Type: Application
    Filed: June 16, 2003
    Publication date: February 26, 2004
    Applicants: The Gov. of the U.S. of America as represented by the Sec. of the Dept. of Health & Human Services, Johns Hopkins University
    Inventors: David A. Wink, Martin Feelisch, Pasquale Pagliaro, David A. Kass, Nazareno Paolocci, Katrina M. Miranda, Jon M. Fukuto