Patents by Inventor Katsuhiko FUKADA

Katsuhiko FUKADA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing Hib conjugate vaccine using PRP with lowered molecular weight
    Patent number: 11027005
    Abstract: A method for preparing a PRP conjugate having high storage stability and a method for producing a Hib conjugate vaccine are provided. A method for preparing PRP conjugate in accordance with the embodiments of the present invention is characterized by that the release of PRPs after preparing the PRP conjugate is suppressed by using PRP with a lowered molecular weight than native PRP for a coupling reaction between PRP and a carrier protein. Also, a Hib conjugate vaccine comprising as an antigen the PRP conjugate prepared by said method has excellent storage stability and maintain sufficient immunogenicity.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: June 8, 2021
    Assignee: KM BIOLOGICS CO., LTD.
    Inventors: Makoto Moriyama, Katsuhiko Fukada, Kazuhiko Kimachi, Yuki Mihara, Hiroshi Yonemura, Yoichiro Kino
  • METHOD FOR PRODUCING Hib CONJUGATE VACCINE USING PRP WITH LOWERED MOLECULAR WEIGHT
    Publication number: 20200046822
    Abstract: A method for preparing a PRP conjugate having high storage stability and a method for producing a Hib conjugate vaccine are provided. A method for preparing PRP conjugate in accordance with the embodiments of the present invention is characterized by that the release of PRPs after preparing the PRP conjugate is suppressed by using PRP with a lowered molecular weight than native PRP for a coupling reaction between PRP and a carrier protein. Also, a Hib conjugate vaccine comprising as an antigen the PRP conjugate prepared by said method has excellent storage stability and maintain sufficient immunogenicity.
    Type: Application
    Filed: October 11, 2017
    Publication date: February 13, 2020
    Applicant: KM Biologics Co., Ltd.
    Inventors: Makoto MORIYAMA, Katsuhiko FUKADA, Kazuhiko KIMACHI, Yuki MIHARA, Hiroshi YONEMURA, Yoichiro KINO