Patents by Inventor Katsuhiko SEKIMATA

Katsuhiko SEKIMATA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BMP-signal-inhibiting compound
    Patent number: 10954216
    Abstract: The present invention relates to novel and excellent small-molecule-compounds that specifically antagonize BMP signal pathways, and these compounds can be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus can be used to treat diseases or pathological symptoms related to BMP signal pathway including inflammation, cardiovascular diseases, hematopoietic diseases, cancer, osteodystrophia, or the like, particularly, fibrodysplasia ossificans progressiva, and the present invention relates to provision of a pharmaceutical and pharmacological agent used for specifically antagonizing the BMP signal pathways and acting on the BMP signal pathways in the prevention and treatment or experimental application since the compounds can be beneficial for regulating cell differentiation and/or cell proliferation.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 23, 2021
    Assignees: RIKEN, THE UNIVERSITY OF TOKYO
    Inventors: Yoshinobu Hashizume, Katsuhiko Sekimata, Hirokazu Kubota, Hirofumi Yamamoto, Yasuko Koda, Hiroo Koyama, Tomonori Taguri, Tomohiro Sato, Akiko Tanaka, Kohei Miyazono
  • BMP-SIGNAL-INHIBITING COMPOUND
    Publication number: 20190337926
    Abstract: The present invention relates to novel and excellent small-molecule-corn pounds that specifically antagonize BMP signal pathways, and these compounds can be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus can be used to treat diseases or pathological symptoms related to BMP signal pathway including inflammation, cardiovascular diseases, hematopoietic diseases, cancer, osteodystrophia, or the like, particularly, fibrodysplasia ossificans progressiva, and the present invention relates to provision of a pharmaceutical and pharmacological agent used for specifically antagonizing the BMP signal pathways and acting on the BMP signal pathways in the prevention and treatment or experimental application since the compounds can be beneficial for regulating cell differentiation and/or cell proliferation.
    Type: Application
    Filed: December 26, 2017
    Publication date: November 7, 2019
    Applicants: RIKEN, THE UNIVERSITY OF TOKYO
    Inventors: Yoshinobu HASHIZUME, Katsuhiko SEKIMATA, Hirokazu KUBOTA, Hirofumi YAMAMOTO, Yasuko KODA, Hiroo KOYAMA, Tomonori TAGURI, Tomohiro SATO, Akiko TANAKA, Kohei MIYAZONO