Abstract: A fibrinolytic enzyme immobilized on a carrier is stabilized by treating the surface of the carrier on which the enzyme is immobilized with a basic amino acid. The amino acid is preferably histidine, arginine or lysine. Carriers may be inorganic materials, natural polymeric materials or synthetic polymeric materials, in a variety of forms. Fibrinolytic enzymes immobilized include plasmin, brinase, urokinase, streptokinase and tissue plasminogen activator. The stabilized immobilized fibrinolytic enzyme maintains activity better during storage or sterilization.

Abstract: A logic circuit includes a driver transistor and a load transistor formed by a junction type or Schottky barrier type field effect transistor, and an input terminal connected to a gate of the driving transistor. A gate voltage generator is connected to a gate of the load transistor and generates a level higher than the sum of threshold values of the load transistor and the driver transistor and lower than the lowest value of (1) the sum of a built-in voltage of the load transistor and the threshold voltage of the driver transistor and (2) the sum of a built-in voltage of the driver transistor and the threshold voltage of the load transistor.