Abstract: Disclosed is a method for measuring sterol in lipoprotein, comprising: forming a complex by contacting lipoprotein in a sample, a tagged sterol, and a first capture body that specifically binds to the tag and has a labeling substance with each other, the complex comprising the lipoprotein comprising the tagged sterol and the first capture body; and detecting a signal generated by the labeling substance comprised in the complex, wherein in the tagged sterol, the tag is added to C3 position of a sterol skeleton.

Abstract: The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

Abstract: Disclosed is a method for obtaining information about cognitive function of a subject, comprising contacting lipoprotein in a blood sample of a subject with a labeled lipid and measuring the labeled lipid incorporated into the lipoprotein, wherein the obtained measured value is an indicator of cognitive impairment.

Abstract: The present invention addresses the problem of providing a method and a reagent for measuring the uptake capacity of a lipoprotein with higher accuracy. This problem is solved by preparing a lipoprotein incorporating a labeled sterol, by mixing the lipoprotein in a sample and the labeled sterol in the presence of a surfactant having no cyclic structure, and measuring the uptake capacity of the labeled sterol of the lipoprotein.

Abstract: The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

Abstract: The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

Abstract: Disclosed is a method for obtaining information on subject's diabetes, comprising measuring lipoprotein's ability to uptake sterol in a biological sample of a subject, wherein a measured value of ability to uptake sterol per unit volume of the biological sample is an indicator of diabetes onset risk.

Abstract: Provided is a monoclonal antibody or antigen-binding fragment thereof which binds to a peptide consisting of 51st to 110th amino acid sequence or a peptide consisting of 201st to 267th amino acid sequence of an amino acid sequence of SEQ ID NO: 1, and is capable of binding to high-density lipoproteins of (1) to (3) below; (1) high-density lipoprotein that is oxidatively modified, (2) high-density lipoprotein that is not oxidatively modified, and (3) high-density lipoprotein incorporating labeled cholesterol.

Abstract: Provided is a method of measuring a lipoprotein's capacity to accept cholesterol including the steps of bringing a lipoprotein in a sample into contact with labeled cholesterol to incorporate the labeled cholesterol into the lipoprotein, bringing the lipoprotein having the labeled cholesterol into contact with an antibody that binds to a lipoprotein to form a complex of the lipoprotein and the antibody, and measuring the label incorporated into the complex.

Abstract: The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

Abstract: Provided is a method of measuring a lipoprotein's capacity to accept cholesterol including the steps of: bringing a lipoprotein in a sample into contact with labeled cholesterol to incorporate the labeled cholesterol into the lipoprotein; bringing the lipoprotein having the labeled cholesterol into contact with an antibody that binds to a lipoprotein to form a complex of the lipoprotein and the antibody; and measuring the label incorporated into the complex.

Abstract: An increase in the temperature of a sliding bearing can be suppressed, and it is possible to reduce the temperature of the bearing and prevent burning and damage. The bearing is divided in two and composed of a liner and a base metal. The liner is disposed on an inner circumferential side of the bearing, and the base metal is disposed on an outer circumferential side of the bearing. A lower liner of the bearing liner, which is located on a load-receiving side, has a cooling groove formed in an outer circumferential surface thereof and extending along a circumferential direction thereof. A lubricant is cooled in the cooling groove and supplied to reduce the temperature of a shaft-sliding surface of the bearing. The lubricant is supplied to the bearing, increases in temperature due to the cooling and has low viscosity.

Abstract: Disclosed is a turbine rotor blade that is highly manufacturable and capable of reducing the stress caused by centrifugal force. The turbine rotor blade includes: a vane portion having a blade leading edge which is positioned upstream in the distribution direction of working fluid, and a blade trailing edge which is positioned downstream of the blade leading edge; and a blade base portion which is extended unidirectionally on a base side of the vane portion and engaged with a blade groove formed in the outer circumference of a turbine rotor. The turbine rotor circumferential position of the end of the blade base portion on the side toward the blade leading edge is different from the turbine rotor circumferential position of the end of the blade base portion on the side toward the blade trailing edge.

Abstract: An increase in the temperature of a sliding bearing can be suppressed, and it is possible to reduce the temperature of the bearing and prevent burning and damage. The bearing is divided into two and composed of a liner and a base metal. The liner is provided on an inner circumferential side of the bearing, and the base metal is provided on an outer circumferential side of the bearing. A lower liner of the bearing liner, which is located on a load-receiving side, has a cooling groove formed in an outer circumferential surface thereof and extending along a circumferential direction thereof. A lubricant is cooled in the cooling groove and supplied to reduce the temperature of a shaft-sliding surface of the bearing. The lubricant that increases in temperature due to the cooling and has low viscosity is supplied to the bearing.