Abstract: A non-aqueous patch preparation may include a drug solution in which a drug is dissolved in an organic solvent, a lipophilic mass base, and anhydrous silicic acid powders that are insoluble both in the organic solvent and in the lipophilic mass base. The organic solvent is selected from the group consisting of propylene glycol, 1,3-butanediol, polyethylene glycol, and propylene carbonate. The lipophilic mass base comprises an elastomer, a tackifier, and a softening agent wherein the elastomer is styrene-isoprene-styrene copolymer (SIS). The patch preparation has 2% to 10% by weight of the anhydrous silicic acid powders.

Abstract: The present disclosure provides a patch preparation having features that prevent accidental use. In some embodiments, a patch preparation containing a plaster on a support, wherein the plaster comprises a solvent that is a combination of ethyl acetate and n-heptane. The patch preparation can lose its adhesion after the plaster is exposed to air and at least some of the solvent has evaporated, or if the patch is removed from the skin. This feature prevent the used patch from being applied to the skin again, and can prevent accidental use. A method of forming a patch preparation is also disclosed.

Abstract: A polymer (B) essentially contains units represented by the following formulas (1), (2) and (3), wherein the number of moles of unit (1) is 0 to 95, the number of moles of unit (2) is 0 to 50, and the number of moles of unit (3) is 2 to 80 when the total number of moles of units (1), (2) and (3) is 100: In units (1) to (3), “X” is a recurring unit having a benzene ring, in unit (2), —CH3 is substituted on the benzene ring, “m” is an integer of 1-6, unit (3) is obtained by substituting a hydrogen of —CH3 in unit (2) by a substituent “Z” derived from a carboxylic acid or anhydride thereof, “n” is an integer of 1-6 indicative of the number of substitutions, l+n=m, and unit (3) is a unit in which “n” is an integer of 1-6 or a combination thereof.

Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.

Abstract: Provided is a resin composition comprising: a polycarbonate resin (A) containing, as main repeating units, a unit (a-1) represented by the following formula (a-1) and a unit (a-2) represented by the following formula (a-2) (wherein, W represents a C1-20 alkylene group or a C6-20 cycloalkylene group, R represents a branched or linear-chain C1-20 alkyl group or a C6-20 cycloalkyl group optionally substituted, and m represents an integer of 0 to 10) and an acrylic resin (B), and the polycarbonate resin and the acrylic resin are in a weight ratio of 40:60 to 99:1, wherein the resin composition has a single glass transition temperature, which is in the range of 90° C. to 150° C., and the resin composition has excellent transparency, chemical resistance, surface hardness and heat resistance, and has a low photoelastic coefficient.

Abstract: A multilayer body includes at least one layer (C) including a resin composition; and at least one layer (D) including a thermoplastic resin, in which the resin composition includes a polycarbonate resin (A) and an acrylic resin (B) in a weight ratio of 40:60 to 99:1, the polycarbonate resin (A) includes, as main repeating units, a unit (a-1) represented by the following formula (a-1): and a unit (a-2) represented by the following formula (a-2): wherein W represents an alkylene group having 1 to 20 carbon atoms or a cycloalkylene group having 6 to 20 carbon atoms, R represents a branched or linear alkyl group having 1 to 20 carbon atoms, or a cycloalkyl group having 6 to 20 carbon atoms and optionally having a substituent, and m represents an integer of 0 to 10, and the molar ratio of the unit (a-1) and the unit (a-2) (a-1/a-2) is 40/60 to 95/5. The multilayer body has excellent transparency, chemical resistance, surface hardness, and adhesion.

Abstract: A multilayer body includes at least one layer (A) made of a polycarbonate resin (A) whose main repeating units include a unit (a-1) composed of an ether diol residue represented by the following formula (1) and a unit (a-2) composed of a diol residue represented by the following formula (2), and at least one layer (B) containing an aromatic polycarbonate resin (B), wherein the molar ratio of the unit (a-1) is 50 to 96 mol % and the molar ratio of the unit (a-2) is 4 to 50 mol %, with respect to 100 mol % of the total repeating units of the polycarbonate resin (A) and the proportion of the aromatic polycarbonate resin (B) in the layer (B) containing an aromatic polycarbonate resin (B) is 30% by weight or more, and the multilayer body is excellent in heat resistance, impact resistance, surface hardness, adhesion, and chemical resistance.

Abstract: Disclosed is a patch containing a plaster having fentanyl, an adhesive, a volatile hydrocarbon solvent (A), and a heteroatom-containing volatile organic solvent (B).

Abstract: The present invention provides a polycarbonate copolymer having low specific gravity and high surface hardness.

Abstract: The purpose of the present invention is to provide an aqueous preparation for external use, said aqueous preparation comprising an acidic drug such as an arylacetic acid nonsteroidal anti-inflammatory analgesic, having an excellent percutaneous absorbability and giving a good feeling in use. The aqueous preparation for external use comprises the acidic drug or a salt thereof, isostearic acid and an alkanol amine. It is preferred that the aqueous preparation according to the present invention for external use further comprises a C2-6 aliphatic hydroxy acid and has a pH value of 4.5-7.8. The C2-6 aliphatic hydroxy acid is one member or a combination of the same selected from the group consisting of lactic acid, glycolic acid, malic acid, tartaric acid and citric acid.

Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.

Abstract: The purpose of the present invention is to provide an aqueous preparation for external use, said aqueous preparation comprising an acidic drug such as an arylacetic acid nonsteroidal anti-inflammatory analgesic, having an excellent percutaneous absorbability and giving a good feeling in use. The aqueous preparation for external use comprises the acidic drug or a salt thereof, isostearic acid and an alkanol amine. It is preferred that the aqueous preparation according to the present invention for external use further comprises a C2-6 aliphatic hydroxy acid and has a pH value of 4.5-7.8. The C2-6 aliphatic hydroxy acid is one member or a combination of the same selected from the group consisting of lactic acid, glycolic acid, malic acid, tartaric acid and citric acid.

Abstract: A polycarbonate resin containing a structural unit originating from a dihydroxy compound represented by formula (1), having a boric-acid content of 100 ppm or lower and/or a tertiary-amine content of 1000 ppm by weight or lower, and having a terminal phenyl group originating from a diester carbonate represented by formula (2), wherein the concentration of the terminal phenyl group is equal to or greater than 30 ?eq/g. In formula (1), R1, R2, R3, and R4 each independently represent a hydrogen atom, a C1-C10 alkyl group, a C1-C10 alkoxy group, a C3-C20 cycloalkyl group, a C6-C20 cycloalkoxy group, a C6-C10 aryl group, a C7-C20 aralkyl group, a C6-C10 aryloxy group, a C7-C20 aralkyloxy group, or a halogen atom, and the cyclobutane ring indicates a cis-trans isomer mixture, a cis isomer alone, or a trans isomer alone. In formula (2), R5 and R6 each independently represent a substituted or non-substituted aromatic group.

Abstract: An organic phosphorus-based compound which satisfies the following requirements (i) to (viii) and is represented by the following formula (1): (i) the organic purity should be not lower than 98%; (ii) the solubility in 20° C. water should be not higher than 0.1 g/100 g of water; (iii) the total halogen component content should be not higher than 1,000 ppm; (iv) the total volatile organic matter content should be not higher than 800 ppm; (v) the ? pH value should be not larger than 1.0; (vi) the volume standard median diameter should be not larger than 30 ?m; (vii) the maximum particle diameter should be not larger than 200 ?m; and (viii) the standard deviation represented by the following formula should be not larger than 20 ?m. Standard deviation=(d84%+d16%)/2; wherein d84%: particle diameter at a point where the cumulative curve becomes 84% (?m), and d16%: particle diameter at a point where the cumulative curve becomes 16% (?m).

Abstract: The purpose of the present invention is to provide: a novel polymer which has an electro-optical effect; a method for producing such a polymer; and a light control element which uses such a polymer. The present invention relates to a non-crosslinkable polycarbonate which contains a moiety that has electro-optical characteristics. The present invention also relates to a method for producing a polycarbonate, which comprises a step for reacting a bisphenol compound, a diol compound that has electro-optical characteristics, and a phosgene in the presence of an acid binding agent and solvent. The present invention also relates to a light control element which comprises such polycarbonate.

Abstract: To provide a polycarbonate resin having an excellent hue and high heat stability, and a production method and a film thereof. The polycarbonate resin has a carbonate constituent unit represented by the following formula (A), wherein the resin contains a terminal group represented by the following formula (1) or (2) and 0.1 to 500 ppm of an aromatic monohydroxy compound. (In the formula (1), R1 is an alkyl group having 6 to 15 carbon atoms which may be substituted.) (In the formula (2), R2 and R3 are each independently an alkylene group having 1 to 12 carbon atoms which may be substituted. R4 is a hydrogen atom or alkyl group having 1 to 12 carbon atoms which may be substituted. n is an integer of 1 to 20.

Abstract: A multilayer body includes at least one layer (A) made of a polycarbonate resin (A) whose main repeating units include a unit (a-1) composed of an ether diol residue represented by the following formula (1) and a unit (a-2) composed of a diol residue represented by the following formula (2), and at least one layer (B) containing an aromatic polycarbonate resin (B), wherein the molar ratio of the unit (a-1) is 50 to 96 mol % and the molar ratio of the unit (a-2) is 4 to 50 mol %, with respect to 100 mol % of the total repeating units of the polycarbonate resin (A) and the proportion of the aromatic polycarbonate resin (B) in the layer (B) containing an aromatic polycarbonate resin (B) is 30% by weight or more, and the multilayer body is excellent in heat resistance, impact resistance, surface hardness, adhesion, and chemical resistance.

Abstract: The present invention provides a polycarbonate copolymer having low specific gravity and high surface hardness.

Abstract: The present disclosure provides a composition for a non-aqueous patch preparation with excellent adhesibility which can sustainedly release a drug. The patch preparation can improve the adhesibility of the patch preparation and the release property of a drug by the addition of a powder ingredient the long-time sustention of the adhesibility of tape preparations enables an improvement of the transdermal absorbability and the sustained release of a drug.

Abstract: The present invention provides a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.