Abstract: A method of the present invention comprises fractionating a sample solution containing analyte DNA molecules into small droplets, wherein the number M of the droplets is greater than the total number N of the DNA molecules, subjecting an emulsion containing the droplets to, for example, PCR amplification, and detecting the presence or absence (amount) of an amplicon obtained in each droplet by fluorescent detection using an intercalator or the like.

Abstract: A biochemical reaction detection chip capable of controlling the temperature for biochemical reactions including hybridizations and its substrate. The function of the chip is performed by comprising a plurality of islands of a heat conducting material on the membrane of the substrate, the islands being spaced from each other and individually provided with temperature controllers, and the probes immobilized on the substrate.

Abstract: A centrifugal separator of the invention has a centrifugal rotor (10-1), with symmetric rotation axes, having single sample separation chamber in it for centrifuging samples contained in sample solutions, an upper opening passing through to said sample separation chamber in the upper part, members of frameworks capable of being coupled to said upper opening, a rotation driving means, assuming that the direction of said symmetric rotation axis is the first direction, for driving said centrifugal rotor around said rotation axis in the first direction, wherein assuming that two directions intersecting with said first direction are the second and third directions, the length of said sample preparation chamber in said third direction is longer than the length of said sample preparation chamber in said second direction.

Abstract: A method for analyzing nucleic acid comprises sequential steps of obtaining genomic DNA fragments and RNA fragments from a sample taken from a subject; obtaining cDNA fragments to the RNA fragments by a reverse-transcriptase reaction; performing PCR amplification using the genomic DNA fragments and the cDNA fragments as templates to obtain a first PCR amplification product derived from a target region of the genomic DNA fragments and a second PCR amplification product derived from the target region of the cDNA fragments; measuring the amounts of the first PCR amplification product and of the second PCR amplification product for an allele pair from which the genomic DNA fragments and the cDNA fragments are derived; detecting the difference in gene expression between the alleles based on the results of the measurements; and determining the existence or otherwise of genetic abnormality based on the measurement results.

Abstract: A biochemical reaction detection chip capable of controlling the temperature for biochemical reactions including hybridizations and its substrate. The function of the chip is performed by comprising a plurality of islands of a heat conducting material on the membrane of the substrate, the islands being spaced from each other and individually provided with temperature controllers, and the probes immobilized on the substrate.

Abstract: A biochemical reaction detection chip capable of controlling the temperature for biochemical reactions including hybridizations and its substrate. The function of the chip is performed by comprising a plurality of islands of a heat conducting material on the membrane of the substrate, the islands being spaced from each other and individually provided with temperature controllers, and the probes immobilized on the substrate.

Abstract: A biochemical reaction detection chip capable of controlling the temperature for biochemical reactions including hybridizations and its substrate. The function of the chip is performed by comprising a plurality of islands of a heat conducting material on the membrane of the substrate, the islands being spaced from each other and individually provided with temperature controllers, and the probes immobilized on the substrate.

Abstract: An automobile transmission including a peripheral wall having an inner surface comprised in a cross-section of a plurality of curved portions which are continuous in series with each other through inwardly projecting node portions. The configuration of the casing provides a structure of high rigidity so that it is effective to suppress the vibrations of the casing wall and consequently the noise caused by such vibrations. The casing wall is formed with brackets for supporting the reverse idle gear shaft in the vicinity of one of the node portions. This arrangement is also effective to suppress vibrations.