Patents by Inventor Katsuki Yokoo

Katsuki Yokoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2 substituted cephem compounds
    Patent number: 10174053
    Abstract: The compounds of the subject invention are related to 2-substituted cephem compounds, which have a wide antimicrobial spectrum, in particular exhibit potent antimicrobial activity against beta-lactamase producing Gram negative bacteria, and pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: January 8, 2019
    Assignees: Glaxo Group Limited, Shionogi and Co., Ltd.
    Inventors: Toshiaki Aoki, Hiroki Kusano, Xiangmin Liao, Neil David Pearson, Israil Pendrak, Jun Sato, Reema K. Thalji, Kenji Yamawaki, Katsuki Yokoo
  • 2 SUBSTITUTED CEPHEM COMPOUNDS
    Publication number: 20170281532
    Abstract: The compounds of the subject invention are related to 2-substituted cephem compounds, which have a wide antimicrobial spectrum, in particular exhibit potent antimicrobial activity against beta-lactamase producing Gram negative bacteria, and pharmaceutical compositions comprising the same.
    Type: Application
    Filed: April 18, 2017
    Publication date: October 5, 2017
    Inventors: Toshiaki AOKI, Hiroki KUSANO, Xiangmin LIAO, Neil David PEARSON, Israil PENDRAK, Jun SATO, Reema K. THALJI, Kenji YAMAWAKI, Katsuki YOKOO
  • Processes for production of intermediates for 2-alkyl cephem compounds
    Patent number: 9527866
    Abstract: The invention relates to processes for the production of intermediates for preparing 2-alkyl cephem compounds useful as antimicrobial drugs. The invention provides a process which comprises oxidating a compound of the formula (I) or a salt thereof to give a compound of the formula (II) or a salt thereof wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: December 27, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Katsuki Yokoo, Shinya Hisakawa, Kenji Yamawaki, Toshiaki Aoki, Yutaka Yokota, Masatoshi Takeo, Mikito Asai
  • Cephem compound having catechol or pseudo-catechol structure
    Patent number: 9334289
    Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: May 10, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Toshiaki Aoki, Jun Sato, Kenji Yamawaki, Katsuki Yokoo, Masayuki Sano
  • 2-SUBSTITUTED CEPHEM COMPOUNDS
    Publication number: 20150299223
    Abstract: The present invention relates to 2-substituted cephem compounds of Formula (I) having a quaternary ammonium group on the 3-side chain, preferably together with a cathechol group, or pharmaceutically acceptable salts thereof, which exhibit potent antimicrobial spectrum against a variety of bacteria including Gram negative bacteria and/or Gram positive bacteria, corresponding pharmaceutical compositions, methods of making, treatment methods for bacterial infections or uses thereof.
    Type: Application
    Filed: October 29, 2013
    Publication date: October 22, 2015
    Inventors: Toshiaki AOKI, Hiroki KUSANO, Xiangmin LIAO, Neil David PEARSON, Israil PENDRAK, Jun SATO, Reema THALGI, Kenji YAMAWAKI, Katsuki YOKOO
  • PROCESSES FOR PRODUCTION OF INTERMEDIATES FOR 2-ALKYL CEPHEM COMPOUNDS
    Publication number: 20150291619
    Abstract: The invention relates to processes for the production of intermediates for preparing 2-alkyl cephem compounds useful as antimicrobial drugs. The invention provides a process which comprises oxidating a compound of the formula (I) or a salt thereof to give a compound of the formula (II) or a salt thereof wherein each symbol is as defined in the specification.
    Type: Application
    Filed: October 29, 2013
    Publication date: October 15, 2015
    Inventors: Katsuki Yokoo, Shinya Hisakawa, Kenji Yamawaki, Toshiaki Aoki, Yutaka Yokota, Masatoshi Takeo, Mikito Asai
  • NOVEL CEPHEM COMPOUND HAVING CATECHOL OR PSEUDO-CATECHOL STRUCTURE
    Publication number: 20140088302
    Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.
    Type: Application
    Filed: April 25, 2012
    Publication date: March 27, 2014
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Yasuhiro Nishitani, Toshiaki Aoki, Jun Sato, Kenji Yamawaki, Katsuki Yokoo, Masayuki SANO