Abstract: An image processing device of a radiation image acquisition device (100) uses a weighted filter to perform a smoothing (processing S102) on an image obtained by counting the number of incident gamma rays. The image processing device suppresses pixel values of a threshold value or less on the smoothed image (processing S103). Further, the image processing device again applies a weighted and smoothing filter to the image processed by a threshold-value processing, to expand the pixels of the accumulation portion (processing S104); thus providing an image that facilitates finding the accumulation portion of a radioisotope.

Abstract: A radiation imaging apparatus comprises display means for displaying an image obtained by imaging an object and light projection means for projecting a light projection mark onto the object, and displays a light projection position on the object onto which the light projection mark is projected on the image. The light projection mark is projected as a line of intersection which is perpendicular to the surface of a detector and at which two planar flat light beams visually intersect each other, and the light projection position on the image is moved according to the movements of the flat light beams. By calculating projected lines obtained by projecting the light projection lines projected onto the object by the flat light beams onto the surface and displaying the projected lines on the image, the light projection position is displayed as a point of intersection of the projected lines on the image.

Abstract: A collimator, a radiological imaging apparatus and a nuclear medicine diagnosis apparatus which are able to improve the sensitivity are provided. The radiological imaging apparatus has a collimator 11 disposed to oppose a radiological detection device 12 and having through-holes 11a for passing to the radiological detection device 12 gamma rays in a specified direction out of those radiated from an object to be examined. The collimator 11 is produced by mutually coupling a plurality of metal tubular members 11A each having the through-hole 11a with the help of a bonding agent S in alignment with a plurality of detectors 12a constituting the radiological detection device 12.

Abstract: The radiation imaging device acquires incident position information of radiation for each detector by setting the size of a through-hole such that at least one pixel is arrayed in a plane view from a direction perpendicular to the detector plane; arranges a septa in displacing from a boundary line between a detector pair in a plane view from a direction perpendicular to the detector plane; further arranging the septa so as to be orthogonal to the boundary line between the detector pair in a plane view from a direction perpendicular to the detector plane; arranges the top of the through-hole in a plane view from a direction perpendicular to the detector plane, in displacing from the boundary line of the detector pair; and arranges the top of the detectors in a plane view from a direction perpendicular to the detector plane so as to be visible through the through-hole.

Abstract: A radiation imaging system includes a detecting unit including a plurality of radiation detecting elements arranged in a plane for radiation detection, a collimator provided with through holes respectively aligned with the radiation detecting elements and opening in an entrance surface such that radiation from a specified direction is selectively made to fall on the radiation detecting elements. A second case joined to a first case fixed to the side surface of the collimator defines a holding chamber G, and a holder holding the detecting unit is placed in the holding chamber G such that spaces that allow the holder to be moved in a plane parallel to the entrance surface are formed between the holder and the second case. A position adjusting mechanism for adjusting the positional relation between the second case and the holder by moving the holder relative to the second case.

Abstract: The radiation detection module (20) is provided with a semiconductor element (1) having a plurality of pixels (Pn), radiation detection elements (30) in which a plurality of first electrodes (31n) are arranged along one side of the semiconductor element (1), and a second electrode (32m) is disposed astride a plurality of pixels (Pn) along the other side, and which output detection signals when a radioactive ray comes incident on the detection pixels (Pn), and a support PCB (21) placed to stand along the direction in which the radioactive ray comes incident. The support PCB (21) has a connection section (21a) detachably connectable to an external connecting section. Radiation detection elements (30) are connected on the support PCB (21) to fabricate a signal read-out circuit having mutually-perpendicular wiring in a pseudo way and that the incident position of the radioactive ray is identified by coincidence determination of the detection signals.

Abstract: A collimator, a radiological imaging apparatus and a nuclear medicine diagnosis apparatus which are able to improve the sensitivity are provided. The radiological imaging apparatus has a collimator 11 disposed to oppose a radiological detection device 12 and having through-holes 11a for passing to the radiological detection device 12 gamma rays in a specified direction out of those radiated from an object to be examined. The collimator 11 is produced by mutually coupling a plurality of metal tubular members 11A each having the through-hole 11a with the help of a bonding agent S in alignment with a plurality of detectors 12a constituting the radiological detection device 12.

Abstract: A method of treating a malignant tumor selected from the group consisting of leukemia, colorectal cancer, ovarian cancer, oral cancer, lung carcinoma, breast carcinoma, prostate carcinoma, and melanoma by administering to a patient in need thereof an effective amount of at least one compound represented by formula (1) wherein A, X, Q, R1-3, and n are defined herein.

Abstract: A radiological imaging apparatus using a semiconductor radiation detector to make it possible to reduce a radiation measurement off time that may result from an attempt to avoid polarization, the radiological imaging apparatus comprising a capacitor that applies a voltage to a semiconductor radiation detector that detects a radiation from a subject, first current regulated means for conducting a charge current to the capacitor, and second current regulated means for conducting a discharge current from the capacitor, or comprising a capacitor that applies a voltage to the semiconductor radiation detector, a first resistor that conducts a charge current to and a discharge current from the capacitor, and a second resistor connected in parallel with the first resistor to subject the capacitor to charging and discharging.

Abstract: A radiation imaging apparatus comprises display means for displaying an image obtained by imaging an object and light projection means for projecting a light projection mark onto the object, and displays a light projection position on the object onto which the light projection mark is projected on the image. The light projection mark is projected as a line of intersection which is perpendicular to the surface of a detector and at which two planar flat light beams visually intersect each other, and the light projection position on the image is moved according to the movements of the flat light beams. By calculating projected lines obtained by projecting the light projection lines projected onto the object by the flat light beams onto the surface and displaying the projected lines on the image, the light projection position is displayed as a point of intersection of the projected lines on the image.

Abstract: A radiation imaging system is configured by a collimator 30A including a detector 21 with a discrete detection pixel corresponding with a pixel and a plurality of radiation passages 31 and looks into a plurality of detectors 21 through one radiation passage 31 to set a step width of rotation around a rotation center axis X1 only for an angle ?p made by lines provided by connecting a center detector 21 of the radiation passage 31 and the adjacent two detectors 21. In the case of generating a flat plane projection image for one direction, radio-graphing is carried out on a projection image in a plurality of predetermined angle positions (??p, 0, +?p) in the circumferential direction of the rotation center axis X1 and thereby one plane projection image is obtained.

Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.

Abstract: In a gamma camera, a plurality of radiation detector elements having a rod-shaped first electrode, a semiconductor device surrounds the first electrode to contact with it for entering a radiation, and a second electrode provided for the side surface of the semiconductor device are detachably attached to a holding member. The holding member has a first electrode contact portion contacted with the first electrode and a second electrode contact portion contacted with the second electrode. A collimator in which a plurality of radiation paths provided corresponding to the plurality of radiation detector elements are formed is arranged on the radiation entering side of the plurality of radiation detector elements. A ?-ray detection signal outputted from the first electrode contact portion is sent to a signal processing integrated circuit. A high voltage is applied to the second electrode via the second electrode contact portion.

Abstract: The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.

Abstract: The radiological imaging system which can improve an energy resolution and perform a diagnosis with high accuracy includes a bed for carrying an examinee H, first and second imaging apparatuses and disposed along the longitudinal direction of the bed. The first imaging apparatus has a plurality of semiconductor radiation detectors for detecting ?-rays emitted from the examinee H, arranged around the bed, the second imaging apparatus has an X-ray source for emitting X-rays to the examinee H and a radiation detector for detecting X-rays which have been emitted from the X-ray source and passed through the examinee H, and the bed is shared by the first imaging apparatus and the second imaging apparatus.

Abstract: A nuclear medial diagnosis apparatus is used for performing diagnosis by administering a medicine marked with a radioactive isotope into an examinee and by using an image obtained by detecting gamma rays emitted from a particular organ or tumor where the medicine is accumulated. An image (an image created by an image creation unit) is created by a signal (a signal as an output from a radiation detector) corresponding to the energy of the gamma ray detected by a radiation detector. The image includes a contamination component attributed to gamma scattering in the radiation detector. An image correction operation unit performs a convolution operation to obtain a contamination image. The contamination image is subtracted by a corrected image creation unit. Thus, it is possible to prevent image degradation by the gamma ray scattering in the radiation detector.

Abstract: The semiconductor radiological detector 1 minimizes a dead space resulting from the draw-out of a signal line from an electrode and which allows a number of semiconductor devices to be densely arranged to improve sensitivity and spatial resolution. The semiconductor radiological detector 1 comprises a semiconductor device 2, an anode 3 attached to one surface of the semiconductor device 2, and a cathode 4 attached to the other surface of the semiconductor device 2. A signal line 5 is provided on the anode 3; the signal line 5 extends straight from the anode 3 and is connected to an X axis wire 12. Another signal line 13 is provided on the cathode 4; the signal line 13 extends straight from the cathode 4 and is connected to a Y axis wire 14.

Abstract: A radiation imaging system is configured by a collimator 30A including a detector 21 with a discrete detection pixel corresponding with a pixel and a plurality of radiation passages 31 and looks into a plurality of detectors 21 through one radiation passage 31 to set a step width of rotation around a rotation center axis X1 only for an angle ?p made by lines provided by connecting a center detector 21 of the radiation passage 31 and the adjacent two detectors 21. In the case of generating a flat plane projection image for one direction, radio-graphing is carried out on a projection image in a plurality of predetermined angle positions (??p, 0, +?p) in the circumferential direction of the rotation center axis X1 and thereby one plane projection image is obtained.

Abstract: A radiological imaging apparatus using a semiconductor radiation detector to make it possible to reduce a radiation measurement off time that may result from an attempt to avoid polarization, the radiological imaging apparatus comprising a capacitor that applies a voltage to a semiconductor radiation detector that detects a radiation from a subject, first current regulated means for conducting a charge current to the capacitor, and second current regulated means for conducting a discharge current from the capacitor, or comprising a capacitor that applies a voltage to the semiconductor radiation detector, a first resistor that conducts a charge current to and a discharge current from the capacitor, and a second resistor connected in parallel with the first resistor to subject the capacitor to charging and discharging.

Abstract: A radiation imaging system includes a detecting unit including a plurality of radiation detecting elements arranged in a plane for radiation detection, a collimator provided with through holes respectively aligned with the radiation detecting elements and opening in an entrance surface such that radiation from a specified direction is selectively made to fall on the radiation detecting elements. A second case joined to a first case fixed to the side surface of the collimator defines a holding chamber G, and a holder holding the detecting unit is placed in the holding chamber G such that spaces that allow the holder to be moved in a plane parallel to the entrance surface are formed between the holder and the second case.