Patents by Inventor Katsuya Kominami
Katsuya Kominami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7282579Abstract: There are provided a polynucleotide encoding human BSSP6 serine protease and a vector and transformed host cells containing this human BSSP6 serine protease encoding polynucleotide.Type: GrantFiled: February 14, 2005Date of Patent: October 16, 2007Assignee: Fuso Pharmaceutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Patent number: 7211425Abstract: There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18 and 20; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP4; an antibody against BSSP4; and a method for detecting BSSP4 in a specimen by using the antibody.Type: GrantFiled: June 29, 2006Date of Patent: May 1, 2007Assignee: Fuso Pharmaceutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Publication number: 20060239994Abstract: There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18 and 20; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP4; an antibody against BSSP4; and a method for detecting BSSP4 in a specimen by using the antibody.Type: ApplicationFiled: June 29, 2006Publication date: October 26, 2006Applicant: FUSO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Patent number: 7029909Abstract: A protein expression vector containing (a) a nucleotide sequence encoding an IgG(?) or a trypsin secretory signal peptide, (b) a nucleotide sequence encoding a polyhistidine amino acid sequence, (c) a nucleotide sequence encoding an amino acid sequence comprising amino acid residues 36–40 of SEQ ID NO:19 (Asp-Asp-Asp-Asp-Lys), which is cleavable by an enterokinase, and (d) a cloning site into which a nucleotide sequence encoding a target protein can be inserted, wherein (a), (b), (c) and (d) are assembled within the vector in the order recited.Type: GrantFiled: November 19, 1999Date of Patent: April 18, 2006Assignee: Fuso Pharmaceutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Patent number: 6998245Abstract: There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2 and 4; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP5; an antibody against BSSP5; and a method for detecting BSSP5 in a specimen by using the antibody. The BSSP5 provied by the present invention can be used for treating and diagnosing various diseases such as Alzheimer's disease (AD), epilepsy, cancer, inflammation, sterility and prostatic hypertropy and detecting pancreatitis in various tissues including brain, prostate gland, placenta, pancreas and spleen.Type: GrantFiled: November 19, 1999Date of Patent: February 14, 2006Assignee: FUSO Pharmaceutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Publication number: 20050170415Abstract: There are provided a human BSSP6 serine protease and a pharmaceutical composition containing this serine protease. Also provided is an antibody to this serine protease or to a fragment thereof.Type: ApplicationFiled: February 14, 2005Publication date: August 4, 2005Applicant: FUSO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Publication number: 20050165223Abstract: There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8 and 10; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP2; an antibody against BSSP2; and a method for detecting BSSP2 in a specimen by using the antibody.Type: ApplicationFiled: March 24, 2005Publication date: July 28, 2005Applicant: FUSO PHARMACEUTICAL INDUSTRIES, LTD.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Patent number: 6921658Abstract: There are provided a human BSSP6 serine protease and a pharmaceutical composition containing this serine protease. Also provided is an antibody to this serine protease or to a fragment thereof.Type: GrantFiled: November 19, 1999Date of Patent: July 26, 2005Assignee: Fuso Pharmacutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Patent number: 6908756Abstract: There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8 and 10; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP2; an antibody against BSSP2; and a method for detecting BSSP2 in a specimen by using the antibody.Type: GrantFiled: November 19, 1999Date of Patent: June 21, 2005Assignee: Fuso Pharmaceutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Publication number: 20050053983Abstract: There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18 and 20; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP4; an antibody against BSSP4; and a method for detecting BSSP4 in a specimen by using the antibody.Type: ApplicationFiled: November 16, 2004Publication date: March 10, 2005Applicant: Fuso Pharmaceutical Industries, Ltd.Inventors: Hidetoshi Uemura, Akira Okui, Katsuya Kominami, Nozomi Yamaguchi, Shinichi Mitsui
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Patent number: 6645734Abstract: A monoclonal antibody binding selectively to neurosin obtained from hybridomas, in particular, strain 2B2-6 and strain S2E5 showing stable proliferation ability. These hydridomas are obtained by fusing mouse spleen cells having a high antibody titer against neurosin with mouse-derived myeloma cells, screening fused cells being highly reactive with neurosin, and thus producing an antibody binding specifically to neurosin. By using this antibody, various diseases in which neurosin participates can be diagnosed.Type: GrantFiled: December 21, 2000Date of Patent: November 11, 2003Assignee: Fuso Pharmaceutical Industries, Ltd.Inventors: Katsuya Kominami, Akira Okui, Shinichi Mitsui, Nozomi Yamaguchi
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Publication number: 20010016331Abstract: A monoclonal antibody binding selectively to neurosin obtained from hybridomas, in particular, strain 2B2-6 and strain S2E5 showing stable proliferation ability. These hydridomas are obtained by fusing mouse spleen cells having a high antibody titer against neurosin with mouse-derived myeloma cells, screening fused cells being highly reactive with neurosin, and thus producing an antibody binding specifically to neurosin. By using this antibody, various diseases in which neurosin participates can be diagnosed.Type: ApplicationFiled: December 21, 2000Publication date: August 23, 2001Inventors: Katsuya Kominami, Akira Okui, Shinichi Mitsui, Nozomi Yamaguchi