Abstract: Low molecular weight compound exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof:

Abstract: An object of the present invention is to provide a novel low molecular weight compound exhibiting an osteogenesis-promoting action. This object is achieved by a compound having the general formula (I) or a pharmacologically acceptable salt thereof. In the general formula (I), R1 and R2 represent hydrogen atoms, and the like; R3 represents a hydrogen atom, and the like; X, Y, and Z represent nitrogen atoms, and the like; A represents a phenylene group, and the like; n represents 1 or 2, and the like; and V and W represent oxygen atoms, and the like.

Abstract: Low molecular weight compound exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof:

Abstract: Compounds exhibiting an osteogenesis-promoting action having the general formula (I) or a pharmacologically acceptable salt thereof: wherein A is selected from among a 3- to 10-membered heterocyclyl group, B is selected from among an amino group, and X is selected from N and CH.

Abstract: An oil discharge structure of a baffle plate for discharging oil from a space of a gear side to a space of a transmission side with a space-saving design is provided. A slit is formed in a side face plate facing a final gear of a case side baffle plate to discharge the oil from an oil volume X in the circumference of the final gear to an oil volume Y stored in a clearance between the case side baffle plate and the transmission case, and in a clearance between the housing side baffle plate and the housing. This provides a compact structure that is not larger in a radial direction of the final gear and discharges the oil in the oil volume X.

Abstract: An oil discharge structure of a baffle plate for discharging oil from a space of a gear side to a space of a transmission side with a space-saving design is provided. A slit is formed in a side face plate facing a final gear of a case side baffle plate to discharge the oil from an oil volume X in the circumference of the final gear to an oil volume Y stored in a clearance between the case side baffle plate and the transmission case, and in a clearance between the housing side baffle plate and the housing. This provides a compact structure that is not larger in a radial direction of the final gear and discharges the oil in the oil volume X.

Abstract: A compound of the formula (I) wherein R1 and R2 is a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group. A is CH2, CO or SO2. B is a single bond, alkylene or alkenylene. D is O or S. E is alkylene or alkenylene. wherein G is a substituted or unsubstituted cycloalkene ring, or a substituted cycloalkane ring. Ar is a substituted or unsubstituted aryl ring, or a substituted or unsubstituted heteroaryl ring. R3 is alkyl. n is 1-3. The invention includes a pharmacologically acceptable salt, ester or other derivative of a compound of the formula (I). The invention also provides pharmaceutical compositions and methods of treating specified diseases utilizing a compound of formula (I).

Abstract: Compounds of the formula and quaternary ammonium ions thereof, wherein R1 and R2 are the same or different and are carbocyclic aryl or aromatic heterocyclic; A is methylene, carbonyl or sulfonyl; B is a single bond, C1-C4 alkylene or C2-C4 alkenylene; D is oxygen or sulfur; E is C2-C6 alkylene, C1-C6 haloalkylene, C3-C6 cycloalkane-1,1-diyl or C3-C6-cycloalkane-1,1-diylmethyl; G is C1-C4 alkylene or C2-C4 alkenylene; and L is —NR3 or —C(R4)(R5), wherein R3 is a carbocyclic aryl or an aromatic heterocyclic; R4 is hydrogen, carbocyclic aryl or aromatic heterocyclic; R5 is —COR6, C1-C6 alkyl, C1-C6 alkoxy, amino, or acylamino, wherein R6 is C1-C6 alkyl or C1-C6 alkoxy, or R4 and R5 together with the carbon atom to which they are attached represent a C5-C10 cycloalkyl or a C5-C10 heterocyclic. The compounds have tachykinin receptor antagonist activity and exhibit an activity against both the NK1 and NK2 receptors.

Abstract: In a mouse having two click switches with buttons, a motion detector and an additional control switch mechanism for a function of scrolling are provided. The additional control switch mechanism includes a first, a second, and a third switch for producing an up-scroll signal, a down-scroll signal, and a scroll mode selection signal, respectively when being actuated. A single actuator rod having a top push button is disposed to be able to incline opposite directions to selectively actuate the first and second switches and to be pushed down to actuate the third switch. The top push button is disposed between the click switch buttons. Alternatively, the third switch with a push button thereof is disposed at a sidewall of the mouse. In another arrangement, the third switch and the push button thereof are disposed between the two click switch mechanisms, and the first switch a push button thereof and the second switch with a push button thereof are disposed in a sidewall of the mouse.

Abstract: Compounds of the formula and quaternary ammonium ions thereof, wherein R.sup.1 and R.sup.2 are the same or different and are carbocyclic aryl or aromatic heterocyclic; A is methylene, carbonyl or sulfonyl; B is a single bond, C.sub.1 -C.sub.4 alkylene or C.sub.2 -C.sub.4, alkenylene; D is oxygen; E is C.sub.2 alkylene; G is C.sub.1 -C.sub.4 alkylene or C.sub.2 -C.sub.4 alkenylene; and L is --C(R.sup.4)(R.sup.5), wherein R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent a C.sub.5 -C.sub.10 cycloalkyl or a C.sub.5 -C.sub.10 heterocyclic. Especially preferred are compounds wherein L represents ##STR1## wherein J is a C.sub.1 -C.sub.6 alkylene; Ar is a ring carbocyclic or aromatic heterocyclic and S*.fwdarw.O is a sulfoxide in which the sulfur atom is in the 5-configuration. The compounds have tachykinin receptor antagonist activity and exhibit an activity against both the NK.sub.1 and NK.sub.2 receptors.