Patents by Inventor Katsuyuki Okubo

Katsuyuki Okubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10206985
    Abstract: The present invention provides a cancer vaccine composition for mucosal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a cellular immunity induction promoter. The composition efficiently induces cellular immunity against a cancer in a subject.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: February 19, 2019
    Assignees: NITTO DENKO CORPORATION, OSAKA UNIVERSITY
    Inventors: Daisuke Asari, Kyohei Matsushita, Arimichi Okazaki, Yoshiki Maeda, Katsuyuki Okubo, Mitsuhiko Hori, Haruo Sugiyama
  • Patent number: 10195258
    Abstract: The present invention provides a cancer vaccine tape preparation for inducing cellular immunity, comprising: a support, an adhesive layer comprising an adhesive disposed on one side of the support, wherein the adhesive layer carries a combination of: (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a first cellular immunity induction promoter. The tape preparation can provides high efficacy.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: February 5, 2019
    Assignees: NITTO DENKO CORPORATION, OSAKA UNIVERSITY
    Inventors: Yoshiki Maeda, Katsuyuki Okubo, Daisuke Asari, Arimichi Okazaki, Takuya Shishido, Mitsuhiko Hori, Haruo Sugiyama
  • Publication number: 20180326042
    Abstract: The present invention provides a dried influenza vaccine preparation in which the activity of an influenza vaccine can be stably maintained even if the preparation is stored without strict temperature control and which can be stably supplied. The present invention also provides a method for producing the dried influenza vaccine preparation. Provided is a dried influenza vaccine preparation including: an influenza vaccine antigen; a disaccharide; and an-amino acid.
    Type: Application
    Filed: November 28, 2016
    Publication date: November 15, 2018
    Applicant: NITTO DENKO CORPORATION
    Inventors: Eiji KIYOTOH, Mitsuhiko HORI, Daisuke ASARI, Katsuyuki OKUBO, Takuya SHISHIDO, Masahiro FUKASAKA, Kyohei MATSUSHITA
  • Publication number: 20180326041
    Abstract: The present invention provides a vaccine pharmaceutical composition for oral administration that enables stable storage of an influenza virus antigen and a method for producing the pharmaceutical composition. Provided is a vaccine pharmaceutical composition for oral administration containing an influenza virus antigen, an excipient, a disaccharide, and an amino acid.
    Type: Application
    Filed: November 28, 2016
    Publication date: November 15, 2018
    Applicant: NITTO DENKO CORPORATION
    Inventors: Takuya SHISHIDO, Daisuke ASARI, Eiji KIYOTOH, Kyohei MATSUSHITA, Wenjing LI, Masahiro FUKASAKA, Katsuyuki OKUBO, Mitsuhiko HORI
  • Patent number: 10092642
    Abstract: The present invention aims at providing a mucosal vaccine composition that can be administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and is capable of safely and effectively inducing the systemic immune response and mucosal immune response.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: October 9, 2018
    Assignee: NITTO DENKO CORPORATION
    Inventors: Masahiro Fukasaka, Mitsuhiko Hori, Katsuyuki Okubo, Daisuke Asari, Arimichi Okazaki, Eiji Kiyotoh, Kyohei Matsushita
  • Patent number: 10076491
    Abstract: The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction promoter.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: September 18, 2018
    Assignee: NITTO DENKO CORPORATION
    Inventors: Daisuke Asari, Katsuyuki Okubo, Takuya Shishido, Arimichi Okazaki, Yoshiki Maeda, Kyohei Matsushita, Wenjing Li, Mitsuhiko Hori, Haruo Sugiyama
  • Patent number: 10071155
    Abstract: The present invention provides a nasal mucosal vaccine composition which is safe, useful as a preventive or therapeutic agent for infectious diseases or cancers, and capable of inducing systemic immune responses and mucosal immune responses effectively.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: September 11, 2018
    Assignee: NITTO DENKO CORPORATION
    Inventors: Eiji Kiyotoh, Mitsuhiko Hori, Katsuyuki Okubo, Daisuke Asari, Arimichi Okazaki, Masahiro Fukasaka, Kyohei Matsushita
  • Patent number: 10071051
    Abstract: The present invention provides a cancer vaccine composition for transdermal administration for cellular immunity induction, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a pharmacologically acceptable acid as a first cellular immunity induction promoter, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: September 11, 2018
    Assignees: NITTO DENKO CORPORATION, OSAKA UNIVERSITY
    Inventors: Katsuyuki Okubo, Yoshiki Maeda, Arimichi Okazaki, Daisuke Asari, Takuya Shishido, Mitsuhiko Hori, Haruo Sugiyama
  • Publication number: 20180147235
    Abstract: The present invention provides an allergy vaccine composition that is useful as a prophylactic or therapeutic agent for an allergic disease and can safely and effectively induce immune tolerance. The vaccine composition is to be administered to a human or animal with an allergic disease for the prevention or treatment of the allergic disease.
    Type: Application
    Filed: April 28, 2016
    Publication date: May 31, 2018
    Applicant: NITTO DENKO CORPORATION
    Inventors: Kyohei MATSUSHITA, Masahiro FUKASAKA, Takuya SHISHIDO, Daisuke ASARI, Katsuyuki OKUBO, Mitsuhiko HORI
  • Patent number: 9962439
    Abstract: The present invention aims at providing an injectable vaccine composition that is safe, useful as a prophylactic or therapeutic agent for cancers or infectious diseases, and capable of inducing the systemic immune response safely and effectively.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: May 8, 2018
    Assignee: NITTO DENKO CORPORATION
    Inventors: Kyohei Matsushita, Masahiro Fukasaka, Arimichi Okazaki, Eiji Kiyotoh, Katsuyuki Okubo, Daisuke Asari, Mitsuhiko Hori
  • Patent number: 9765731
    Abstract: A canister arrangement structure for a saddle-ride type vehicle in which a canister for adsorbing evaporated fuel in a fuel tank is disposed below a step floor on which an occupant's foot is placed, the step floors are configured as a left and right pair and are supported from below by left and right step frames that extend back and forth at a position on the side of the main frame of the vehicle. The canister is supported by the one step frame.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 19, 2017
    Assignee: HONDA MOTOR CO., LTD.
    Inventors: Katsuyuki Okubo, Masanori Nakamura, Masashi Nagayama, Tetsunori Iwamoto, Takasumi Yamanaka, Matake Sugeno
  • Publication number: 20170246287
    Abstract: Disclosed is a vaccine composition for transdermal administration to induce cellular immunity, comprising an antigen, wherein Th1 cell ratio in a model animal for immunological evaluation that received the composition is 10% or more.
    Type: Application
    Filed: October 28, 2016
    Publication date: August 31, 2017
    Applicant: NITTO DENKO CORPORATION
    Inventors: Takuya SHISHIDO, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Yoshiki MAEDA, Kyohei MATSUSHITA, Wenjing LI, Mitsuhiko HORI, Haruo SUGIYAMA
  • Publication number: 20170216431
    Abstract: The present invention provides a vaccine pharmaceutical composition for transdermal administration which is safe, usable as a prophylactic or therapeutic agent for cancer or infectious diseases, and capable of safely and effectively inducing a systemic immune response.
    Type: Application
    Filed: October 1, 2015
    Publication date: August 3, 2017
    Applicant: NITTO DENKO CORPORATION
    Inventors: Takuya SHISHIDO, Daisuke ASARI, Kyohei MATSUSHITA, Katsuyuki OKUBO, Mitsuhiko HORI
  • Publication number: 20170007703
    Abstract: The present invention provides a skin penetration-accelerating composition that eliminates the need for forming a drug into a particle structure and dramatically improves the skin penetration properties of a drug without breaking the skin tissue. The present invention also provides a preparation for transdermal administration containing the skin penetration-accelerating composition and a patch preparation containing the skin penetration-accelerating composition. The present invention provides a skin penetration-accelerating composition containing a flavonoid compound and a surfactant and used for accelerating skin penetration of a drug.
    Type: Application
    Filed: January 28, 2015
    Publication date: January 12, 2017
    Applicant: NITTO DENKO CORPORATION
    Inventors: Kyohei MATSUSHITA, Yoshiki MAEDA, Wenjing LI, Katsuyuki OKUBO, Mitsuhiko HORI
  • Publication number: 20170000751
    Abstract: The present invention provides a skin penetration-accelerating composition that eliminates the need for forming a drug into a particle structure and dramatically improves the skin penetration properties of a drug without breaking the skin tissue. The present invention also provides a preparation for transdermal administration containing the skin penetration-accelerating composition and a patch preparation containing the skin penetration-accelerating composition. The present invention provides a skin penetration-accelerating composition containing a flavonoid compound and used for accelerating skin penetration of a drug.
    Type: Application
    Filed: January 28, 2015
    Publication date: January 5, 2017
    Applicant: NITTO DENKO CORPORATION
    Inventors: Yoshiki MAEDA, Kyohei MATSUSHITA, Wenjing LI, Katsuyuki OKUBO, Mitsuhiko HORI
  • Publication number: 20160287697
    Abstract: The present invention aims at providing an injectable vaccine composition that is safe, useful as a prophylactic or therapeutic agent for cancers or infectious diseases, and capable of inducing the systemic immune response safely and effectively.
    Type: Application
    Filed: October 2, 2014
    Publication date: October 6, 2016
    Applicant: NITTO DENKO CORPORATION
    Inventors: Kyohei MATSUSHITA, Masahiro FUKASAKA, Arimichi OKAZAKI, Eiji KIYOTOH, Katsuyuki OKUBO, Daisuke ASARI, Mitsuhiko HORI
  • Publication number: 20160228540
    Abstract: The present invention provides a nasal mucosal vaccine composition which is safe, useful as a preventive or therapeutic agent for infectious diseases or cancers, and capable of inducing systemic immune responses and mucosal immune responses effectively.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 11, 2016
    Applicant: NITTO DENKO CORPORATION
    Inventors: Eiji KIYOTOH, Mitsuhiko HORI, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Masahiro FUKASAKA, Kyohei MATSUSHITA
  • Publication number: 20160213773
    Abstract: The present invention aims at providing a vaccine composition capable of being administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is safe, useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and capable of effectively inducing the systemic immune response and mucosal immune response.
    Type: Application
    Filed: October 2, 2014
    Publication date: July 28, 2016
    Applicant: NITTO DENKO CORPORATION
    Inventors: Masahiro FUKASAKA, Mitsuhiko HORI, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Eiji KIYOTOH, Kyohei MATSUSHITA
  • Publication number: 20160193327
    Abstract: The present invention aims at providing a mucosal vaccine composition that can be administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and is capable of safely and effectively inducing the systemic immune response and mucosal immune response.
    Type: Application
    Filed: October 2, 2014
    Publication date: July 7, 2016
    Applicant: NITTO DENKO CORPORATION
    Inventors: Masahiro FUKASAKA, Mitsuhiko HORI, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Eiji KIYOTOH, Kyohei MATSUSHITA
  • Publication number: 20140234377
    Abstract: The present invention provides a vaccine composition which comprises a cellular immunity induction promoter universally usable against various antigens in cellular immunity induction by mucosal administration of the antigen and exerts a high cellular immunity inducing effect by mucosal administration. The present invention provides a vaccine composition for mucosal administration to induce cellular immunity, comprising: (i) an antigen; and (ii) one or more cellular immunity induction promoters selected from the group consisting of a TLR ligand, a cyclic dinucleotide, a helper peptide and an immunomodulatory small molecule drug.
    Type: Application
    Filed: January 29, 2014
    Publication date: August 21, 2014
    Inventors: Arimichi OKAZAKI, Kyohei MATSUSHITA, Daisuke ASARI, Takuya SHISHIDO, Yoshiki MAEDA, Katsuyuki OKUBO, Wenjing LI, Mitsuhiko HORI, Haruo SUGIYAMA