Patents by Inventor Kavitha Nellore

Kavitha Nellore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS
    Publication number: 20260097019
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 30, 2025
    Publication date: April 9, 2026
    Inventors: Kavitha Nellore, Subramanya Hosahalli
  • Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
    Patent number: 12290507
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: May 6, 2025
    Assignee: Aurigene Oncology Limited
    Inventors: Kavitha Nellore, Subramanya Hosahalli
  • COMPOUNDS AND COMPOSITIONS FOR TREATING HEMATOLOGICAL DISORDERS
    Publication number: 20220339161
    Abstract: The present invention provides methods of treating hematological disorders, such as acute myeloid leukemia, using substituted heterocyclic compounds and pharmaceutically acceptable salts thereof. The compounds inhibit IRAK4 and FLT-3 kinases.
    Type: Application
    Filed: June 29, 2022
    Publication date: October 27, 2022
    Inventors: Venkateshwar Rao Gummadi, Susanta Samajdar, Kavitha Nellore, Girish Daginakatte, Wesley Roy Balasubramanian
  • Compounds and compositions for treating hematological disorders
    Patent number: 11419875
    Abstract: The present invention provides methods of treating hematological disorders, such as acute myeloid leukemia, using substituted heterocyclic compounds and pharmaceutically acceptable salts thereof. The compounds inhibit IRAK4 and FLT-3 kinases.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: August 23, 2022
    Assignee: Aurigene Discovery Technologies Limited
    Inventors: Venkateshwar Rao Gummadi, Susanta Samajdar, Kavitha Nellore, Girish Daginakatte, Wesley R. Balasubramanian
  • METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS
    Publication number: 20220241246
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 14, 2021
    Publication date: August 4, 2022
    Inventors: Kavitha Nellore, Subramanya Hosahalli
  • Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
    Patent number: 11147801
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: October 19, 2021
    Assignee: Aurigene Discovery Technologies Limited
    Inventors: Kavitha Nellore, Subramanya Hosahalli
  • COMPOUNDS AND COMPOSITIONS FOR TREATING HEMATOLOGICAL DISORDERS
    Publication number: 20210290628
    Abstract: The present invention provides methods of treating hematological disorders, such as acute myeloid leukemia, using substituted heterocyclic compounds and pharmaceutically acceptable salts thereof. The compounds inhibit IRAK4 and FLT-3 kinases.
    Type: Application
    Filed: March 30, 2018
    Publication date: September 23, 2021
    Applicant: Aurigene Discovery Technologies Limited
    Inventors: Venkateshwar Rao Gummadi, Susanta Samajdar, Kavitha Nellore, Girish Daginakatte, Wesley R. Balasubramanian
  • METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS
    Publication number: 20200078339
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 19, 2018
    Publication date: March 12, 2020
    Inventors: Kavitha Nellore, Subramanya Hosahalli
  • Methods of Use for Trisubstituted Benzotriazole Derivatives as Dihydroorotate Oxygenase Inhibitors
    Publication number: 20180369206
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: February 20, 2018
    Publication date: December 27, 2018
    Inventors: Kavitha Nellore, Subramanya Hosahalli
  • Methods of Use for Trisubstituted Benzotriazole Derivatives as Dihydroorotate Oxygenase Inhibitors
    Publication number: 20170224663
    Abstract: The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R1, R2 and R3 which have the meanings given in the specification, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 10, 2017
    Applicant: Aurigene Discovery Technologies Limited
    Inventors: Kavitha Nellore, Subramanya Hosahalli