Abstract: A system and methods for managing a patient's medical records and information that use a portable memory device that securely stores the patient's medical records and information. The portable memory device is formatted for designated access by the patient and third parties, wherein access requires authentication and verification by designated persons in non-emergencies, or by security override in emergency situations. The system and methods for managing a patient's medical records and information can be used at a patient's home, at the patient's physician's office, hospital, or pharmacy, and by emergency response team personnel. The system and methods can use home software designed for use on the patient's home computer or a computer designated by the patient for managing the patient's medical records and information.