Abstract: An anti-reflux support system for an infant is disclosed comprising a wedge-shaped support pillow having an inclined infant- supporting surface, an infant torso-encircling sling attachable to the infant-supporting surface of the support pillow, and fasteners carried by at least one of the pillow or the slings for securing the sling on the infant-supporting surface in any one of a plurality of positions. The support pillow includes internal spaced, vertically-oriented support baffles extending between the infant-supporting surface and the bottom surface, and a loose, particulate filler material. The filler material cooperates with the support baffles to impart the wedge-shape to the pillow and to permit the infant-supporting surface to be deformed concavely, and thus conform to the shape of the infant's torso, when the infant is placed on the infant-supporting surface.