Abstract: Provided is an agent for reducing odors of pyrazine derivatives based on an olfactory receptor antagonism. The agent for reducing odors of pyrazine derivatives includes at least one antagonist of olfactory receptor OR5K1 as an active ingredient.

Abstract: Provided is an agent for reducing odors of pyrazine derivatives based on an olfactory receptor antagonism. The agent for reducing odors of pyrazine derivatives includes at least one antagonist of olfactory receptor OR5K1 as an active ingredient.

Abstract: Provided is an agent for reducing odors of pyrazine derivatives based on an olfactory receptor antagonism. The agent for reducing odors of pyrazine derivatives includes at least one antagonist of olfactory receptor OR5K1 as an active ingredient.

Abstract: A method to identify an agent for reducing an odor of a pyrazine derivative, comprising: adding a test substance and a pyrazine derivative represented by the following Formula (I): wherein R1 represents methyl, ethyl, or acetyl; and R2, R3, and R4 each independently represent hydrogen or methyl, to an olfactory receptor OR5K1 or a polypeptide having at least 80% identity to the amino acid sequence of the olfactory receptor OR5K1; measuring a response of the olfactory receptor to the pyrazine derivative; and identifying a test substance inhibiting the response of the olfactory receptor on the basis of the measured response.

Abstract: A self-tanning cosmetic comprising components (A), (B) and (C), and a self-tanning method reducing an odor derived from a compound represented by the following formula (1), comprising a step of application of the cosmetic to the skin for a browning reaction, wherein the cosmetic comprises: (A) dihydroxyacetone; (B) at least one or more compounds selected from the group consisting of 4-methyl-3-decen-5-ol, 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol, 2-hexyl-3-phenyl-2-propenal and 2-methyl-3-(4-iso-propylphenyl)propanal; and (C) at least one or more compounds selected from the group consisting of 3,7-dimethyl-1,6-nonadien-3-ol, 1-(2,2,6-trimethyl-2-cyclohexenyl)-2-buten-1-one, 1-(5,5-dimethyl-1-cyclohexen-1-yl)-4-penten-1-one, 1-(3,3-dimethyl-6-cyclohexen-1-yl)-4-penten-1-one, benzaldehyde and gamma-nonalactone; wherein R1 represents a methyl group, an ethyl group or an acetyl group, and R2, R3 and R4 represent a hydrogen atom or a methyl group.