Abstract: The present invention provides a method of performing analyses and assays involving multiple interactions of reagent-containing fluid flows with liquid and solid target substances. The methods of the invention allow the simultaneous manipulation of different fluids on a small planar surface. The invention also provides a flow cell and method of use thereof for analyzing fluid-fluid and fluid-solid interactions in a substantially planar system. The flow cell contains at least one chamber and a plurality of inlets thereto allowing the introduction of a plurality of fluids in fluidic contact. The cell depth is the smallest dimension of the flow cell, and is of a magnitude, from about 50 to about 1000 microns such that any mixing of adjacent fluids in the chamber is substantially limited to mixing by passive diffusion.

Abstract: A capillary electrophoresis system (10) comprising: a separation capillary (20) with a first distal tip (30) and a second distal tip (140); a source vessel (50) containing a solution (40); a microreservoir-electrode (59) comprising a wire loop; a power source (60) connected to the microreservoir-electrode by wire (57); a control system (200); a detector (90); and a final destination vessel (160) containing electrolyte (150) and a ground electrode (155).