Abstract: The present invention provides capability to instantaneously adjust a height of an operation panel to an optimal height in accordance with a height of an operator with extremely easy operation and slight operating force. The operation panel is attached to a housing side wall of a machine tool in a vertically movable manner, supporting a load of the operation panel by the housing through a gas spring with a hydraulic lock. The operation panel is set to be capable of being vertically adjusted in position by disposing a handling unit which releases the hydraulic lock of the gas spring at the vicinity of the lower side of the operation panel.

Abstract: The present invention provides capability to instantaneously adjust a height of an operation panel to an optimal height in accordance with a height of an operator with extremely easy operation and slight operating force. The operation panel is attached to a housing side wall of a machine tool in a vertically movable manner, supporting a load of the operation panel by the housing through a gas spring with a hydraulic lock. The operation panel is set to be capable of being vertically adjusted in position by disposing a handling unit which releases the hydraulic lock of the gas spring at the vicinity of the lower side of the operation panel.

Abstract: Disclosed are: a recombinant C-terminal ?-amidated enzyme derivative which lacks the formation of at least one disulfide bond among five disulfide bonds occurring in a C-terminal ?-amidated enzyme derived from Xenopus laevis; DNA encoding the derivative; an expression vector carrying the DNA; a bacterium Escherichia coli transformed with the expression vector; and a method for producing the derivative by using the bacterium Escherichia coli.

Abstract: Disclosed are: a recombinant C-terminal ?-amidated enzyme derivative which lacks the formation of at least one disulfide bond among five disulfide bonds occurring in a C-terminal ?-amidated enzyme derived from Xenopus laevis; DNA encoding the derivative; an expression vector carrying the DNA; a bacterium Escherichia coli transformed with the expression vector; and a method for producing the derivative by using the bacterium Escherichia coli.

Abstract: The present invention provides a transformed cell which is transformed by at least one gene of enzymes participating in biosynthesis of tetrahydrobiopterin and a process for the production of a biopterin compound using the same. In accordance with the present invention, the biopterin compound can be produced in large quantities in an industrial advantageous manner from less expensive materials.

Abstract: The present invention provides a transformed cell which is transformed by at least one gene of enzymes participating in biosynthesis of tetrahydrobiopterin and a process for the production of a biopterin compound using the same. In accordance with the present invention, the biopterin compound can be produced in large quantities in an industrial advantageous manner from less expensive materials.

Abstract: The present invention provides a transformed cell which is transformed by at least one gene of enzymes participating in biosynthesis of tetrahydrobiopterin and a process for the production of a biopterin compound using the same. In accordance with the present invention, the biopterin compound can be produced in large quantities in an industrial advantageous manner from less expensive materials.

Abstract: An (R)-2-amino-1-phenylethanol derivative shown by the general formula (IIa) ##STR1## wherein R.sup.1 and R.sup.5 represent a hydrogen atom, etc.; R.sup.2, R.sup.3 and R.sup.4 independently represent a halogen atom, etc., or a salt thereof, can readily be produced (1) by permitting a Microorganism belonging to the genus Rhodosporidium, the genus Comamonas or the like to act on a mixture of corresponding (R)-form and (S)-form to asymmetrically utilize, or (2) by permitting a microorganism belonging to the genus Lodderomyces, the genus Pilimelia or the like to act on a corresponding aminoketone derivative to asymmetrically reduce. An (R,R)-1-phenyl-2-[(2-phenyl-1-alkylethyl) amino]ethanol derivative having a high optical purity can easily be obtained from the compound of the formula (IIa) or a salt thereof. Said derivative is useful as an intermediate for producing an anti-obesity agent and so on.

Abstract: A muffler is connected to a pair of exhaust pipes extending from each cylinder of a multi-cylinder engine. The muffler assures easier assembling work and provides independent exhaust sound for each cylinder. The muffler includes a forward and a rearward expansion chamber within the inside thereof. The expansion chambers are separated in the longitudinal direction by a separation wall extending across the muffler. The exhaust pipe connected to the forward cylinder of a V-type two-cylinder engine is inserted into the forward expansion chamber, while the exhaust pipe connected to the rear cylinder is inserted into the rearward expansion chamber.

Abstract: The object of the present invention is to provide a method for improving productivity in the production of useful substances by animal cells. The present invention discloses a method for animal cell culture to produce a desired substance, comprising the steps of (1) culturing animal cells at a temperature at which the animal cells can grow; and (2) culturing the animal cells at a lower temperature.

Abstract: A small-sized muffler having porous partition walls includes a first expansion chamber, a second expansion chamber, a third expansion chamber and a fourth expansion chamber. A first porous partition wall is longitudinally arranged within the third expansion chamber so as to define a fifth expansion chamber. Similarly, a second porous partition wall is longitudinally arranged within the first expansion chamber so as to define the sixth expansion chamber. The first porous partition wall and the second porous partition wall are provided with small holes over their entire surface. The first porous partition wall and the second porous partition wall are each formed as a convexly curved surface curved toward the center of the muffler around the first feeding pipe and the second feeding pipe, respectively.

Abstract: A process for production of a desired protein comprising the steps of:a culturing animal cells capable of producing the desired protein in a medium containing trichostatin compounds; andrecovering the desired protein from the culture.

Abstract: An (R)-2-amino-1-phenylethanol derivative shown by the general formula (IIa) ##STR1## wherein R.sup.1 and R.sup.5 represent a hydrogen atom, etc.; R.sup.2, R.sup.3 and R.sup.4 independently represent a halogen atom, etc., or a salt thereof, can readily be produced (1) by permitting a microorganism belonging to the genus Rhodosporidium, the genus Comamonas or the like to act on a mixture of corresponding (R)-form and (S)-form to asymmetrically utilize, or (2) by permitting a microorganism belonging to the genus Lodderomyces, the genus Pilimelia or the like to act on a corresponding aminoketone derivative to asymmetrically reduce. An (R,R)-1-phenyl-2-?(2-phenyl-1-alkylethyl) amino!ethanol derivative having a high optical purity can easily be obtained from the compound of the formula (IIa) or a salt thereof. Said derivative is useful as an intermediate for producing an anti-obesity agent and so on.

Abstract: An (R)-2-amino-1-phenylethanol derivative shown by the general formula (IIa) ##STR1## wherein R.sup.1 and R.sup.5 represent a hydrogen atom, etc.; R.sup.2, R.sup.3 and R.sup.4 independently represent a halogen atom, etc., or a salt thereof, can readily be produced (1) by permitting a microorganism to act on a mixture of corresponding (R)-form and (S)-form to asymmetrically utilize, or (2) by permitting a microorganism to act on a corresponding aminoketone derivative to asymmetrically reduce. An (R,R)-1-phenyl-2-[(2-phenyl-1-alkylethyl) amino]ethanol derivative having a high optical purity can easily be obtained from the compound of the formula (IIa) or a salt thereof. Said derivative is useful as an intermediate for producing an anti-obesity agent.