Abstract: The purpose of the present invention is to improve the efficiency and convenience of analyzing the degree of likelihood that a mutation is one that affects the development or progression of a disease. A common filter unit of an analysis device for selecting a cancer driver mutation in a subject classifies, on the basis of a first classification criteria, each of a plurality of sequence mutations identified by sequencing nucleic acids included in the subject into a rank from among rank MYC1 for which the likelihood of being selected as a target sequence mutation is the highest and ranks MYC2 to MYC4 for which the above likelihood is lower than that for MYC1. A parameter-setting reception unit sets, as a second classification criteria, a classification criteria of having been registered in a database or a list, the second classification criteria being different from the first classification criteria for carrying out classification into rank MYC1.

Abstract: The present invention addresses the problem of improving user-friendliness and efficiency in analyzing the extent of possibility that there is a mutation that affects the occurrence or progression of disease. A training unit of an information processing system including an analysis device for selecting cancer driver mutations of a test subject uses a plurality of training information sets to execute machine learning by using, as training information sets regarding a prescribed nucleic acid, information indicating known sequence mutations carrying adverse risks, and at least some clinically significant information regarding mutations from among a public database, a human gene polymorphism database, a database pertaining to drug-gene interactions and genome resources for new drug development, and a drug response database.

Abstract: An analysis method suitable for each SV is provided by utilizing a structural characteristic of the SV. The analysis method is a method for analyzing the presence/absence of a specific structural variation in a sample DNA including a genomic DNA, a free DNA, or a complementary DNA derived from a subject, and including a detection step of detecting the presence/absence of the specific structural variation by performing PCR using the sample DNA as a template, and using, as a primer, a primer pair set consisting of a first primer pair and a second primer pair.

Abstract: An analysis apparatus is provided for analyzing a mutation state, including a mutation location in a base sequence and the content of the mutation, extracted from genetic information of a sample to be analyzed by sequence alignment. The apparatus includes: a receiving unit that receives mutant base sequence information representing the mutation state; a filter processing unit that that outputs a score determined depending on whether or not the mutation state represented by the mutant base sequence information received by the receiving unit is a structural mutation across multiple genes; and an output unit that creates rank information representing the degree of possibility that the mutation state is pathologic based on the score output by the filter processing unit and outputs the created rank information.

Abstract: A legitimacy management system or the like is provided, configured to be suitable for managing history information with legitimacy ensured giving consideration to security. A legitimacy management system 1 includes a user device 3, distribution device 5, and exchange apparatus 7. A splitting engine and combining engine are separately managed by user device 3 and exchange apparatus 7, respectively. User device 3 includes a splitting unit 21. Exchange apparatus 7 includes a combining unit 51. User device 3 instructs splitting unit 21 to split history information into multiple split files, and distributes the split files to user device 3 and the distribution device 5. When the history information is updated, user device 3 issues a request to exchange apparatus 7. In this case, combining unit 51 of exchange apparatus 7 combines the split files to acquire a combined file, and sends the combined file to user device 3.

Abstract: In a hydraulic rotary machine having rotational shaft provided within a casing a rotational shaft, a cylinder block rotationally interlocked with the rotational shaft and formed with a plural number of cylinder bores, and pistons slidably received in the cylinder bores and adapted to slide back and forth within the cylinder bores while the rotational shaft and the cylinder block are put in rotation in synchronism with each other, a multitude of minute pits are formed at least either on sliding surfaces on the side of the cylinder bores, each one of the minute pits are in an elliptical shape defining a moderately sloped surface in one side and an acutely sloped surface in the other side, and the moderately sloped surfaces of the minute pits are oriented to face a direction in which said pistons are put in sliding movement in said cylinder bores under a greater load than in the other direction.

Abstract: In a hydraulic rotary machine having rotational shaft provided within a casing a rotational shaft, a cylinder block rotationally interlocked with the rotational shaft and formed with a plural number of cylinder bores, and pistons slidably received in the cylinder bores and adapted to slide back and forth within the cylinder bores while the rotational shaft and the cylinder block are put in rotation in synchronism with each other, a multitude of minute pits are formed at least either on sliding surfaces on the side of the cylinder bores, each one of the minute pits are in an elliptical shape defining a moderately sloped surface in one side and an acutely sloped surface in the other side, and the moderately sloped surfaces of the minute pits are oriented to face a direction in which said pistons are put in sliding movement in said cylinder bores under a greater load than in the other direction.

Abstract: A light incident into a wedge type light scattering conducting element from a light incident surface of the light scattering conducting element is converted into a light flux having a directionality and is output from a light output surface. The output light is input to a wedge type emitting direction characteristic adjusting element arranged with a positional relationship complementary to the light scattering conducting element. A prism shaped irregularity for adjusting a propagating directionality of the light in longitudinal/transverse directions is formed on a light input surface/light output surface of the wedge type emitting direction characteristic adjusting element. The wedge type emitting direction characteristic adjusting element has a weakened scattering power depending on requirements, thereby a degree of directionality sharpness of the light emitted from a surface light source device is adjusted.

Abstract: An electric wiring block composed of a block main body and various cassette blocks. The block main body includes a plurality of cassette receiving chambers which are identical in shape with each other and into which the cassette blocks are received, and, on the respective inner peripheral walls of the cassette receiving chambers, securing ribs are respectively provided. Also, on the outer peripheral wall of the block main body, external securing ribs for option cassettes are provided, while the external securing ribs are identical in shape with the securing ribs. Further, on the outside portions of the cassette blocks, which are identical in shape with each other and are used in common with different kinds of electric parts, lock claws are provided for inserting the cassette blocks into the cassette receiving chambers, and option lock claws are provided for fixing the cassette blocks to the outside portion of the block main body.

Abstract: Surface light source device having a light conducting member, a light source, a light diffusing member disposed on a front light incidence surface side of the light conducting member, and a light reflecting member arranged on a rear side of the light conducting member; and a refractive index of the light conducting member is arranged to be constant for a distance from the light incidence surface and then to be varied so as to be smaller as farther from the light source, to obtain a bright and uniform brightness distribution.

Abstract: A surface light source device using a light conducting member, in which a multiplicity of concave portions are formed on an opposite surface of a light emitting surface of the light conducting member and the concave portions are arranged to have specific shapes to obtain a bright surface light source with a uniform brightness. A light diffusing material is fulfilled within the concave portions of the light conducting member so that a more uniform brightness can be obtained in an easy manner.

Abstract: A light incident into a wedge type light scattering conducting element from a light incident surface of the light scattering conducting element is converted into a light flux having a directionality and is output from a light output surface. The output light is input to a wedge type emitting direction characteristic adjusting element arranged with a positional relationship complementary to the light scattering conducting element. A prism shaped irregularity for adjusting a propagating directionality of the light in longitudinal/transverse directions is formed on a light input surface/light output surface of the wedge type emitting direction characteristic adjusting element. The wedge type emitting direction characteristic adjusting element has a weakened scattering power depending on requirements, thereby a degree of directionality sharpness of the light emitted from a surface light source device is adjusted.

Abstract: An electric junction box in which electric power is distributed to electric parts or devices, mounted on an upper side of a part-mounting floor portion of an upper case, through bus bars mounted on a lower side of the part-mounting floor portion. In the electric junction box, a peripheral wall of an upper case has a heat-radiating wall portion which projects upwardly beyond the position of mounting of the electric parts on the part-mounting floor portion of the upper case. The heat-radiating wall portion has a bus bar installation space of a slit-like cross-section which is open to the lower surface of the part-mounting floor portion, and receives the connecting plate of the bus bar.

Abstract: A surface light source device having a light conducting member made of a transparent material, a light source disposed on the light incident edge surface of the light conducting member, a light diffusing member disposed on a front surface (light emitting surface) side of the light conducting member, a reflecting member provided on a rear surface side of the light conducting member, a prismatic sheet having a multiplicity of fine prismatic surfaces arranged on the light diffusing member; a pattern having a light diffusing characteristic is provided on the surface of the light conducting member; and the pattern is formed with the aid of half-transparent ink in which fine spherical silicon grains each having a particle diameter of 1 to 10 micrometers are mixed. According to the present invention, therefore a bright surface light source device having a uniform brightness distribution can be obtained.

Abstract: A surface light source device of side light type controls the intensity of light rays emitted therefrom. The surface light source device of side light type comprises a light scattering guide 20 having a light incidence surface 22, a light emission surface 23 and an inclined surface 25. The device further includes a primary light source L arranged around one side of the light incidence surface 22, a silver foil R surrounding the primary light source L, a prism sheet 4 arranged along the light emission surface 23, and a silver foil S arranged along the inclined surface 25. The inclined surface 25 of the light scattering guide 20 composed of three sections I, II and III. The section I is a convex cylindrical surface section having a radius of curvature of 330 mm. The tangential direction at the end of the guide on the side of the light incidence surface 22 is parallel to the light emission surface 23. The tangential direction at the boundary between the sections I and II is inclined at an angle 4.degree.

Abstract: A surface light source device using a light conducting member, in which a multiplicity of concave portions are formed on an opposite surface of a light emitting surface of the light conducting member and the concave portions are arranged to have specific shapes to obtain a bright surface light source with a uniform brightness. A light diffusing material is fulfilled within the concave portions of the light conducting member so that a more uniform brightness can be obtained in an easy manner.

Abstract: A surface light source device comprising at least one light source, a transparent panel, a diffusing panel and a reflecting surface. This surface light source device is configured so that brightness is enhanced in a direction perpendicular to the diffusing panel by disposing, on the side of a front surface of the transparent panel, a transparent sheet which has protrusions having a saw-tooth-like sectional shape formed on one surface thereof.

Abstract: A surface light source device which comprises a light-conducting member consisting of a sheet of transparent material, a linear light source disposed adjacent to an edge surface of the light-conducting member, a diffusion plate disposed on a front surface of the light-conducting member and a reflective plate disposed on a rear side of the light-conducting member. The rear surface of the light-conducting member has depressions or projections. These depressions or projections have rough surfaces. By selecting the shape of the depressions or projections, and controlling the roughness of the rough surfaces, an enhanced uniform brightness distribution is provided.

Abstract: A surface light source device comprising at least one light source, a transparent panel, a diffusing panel and a reflecting surface. This surface light source device is configured so that brightness is enhanced in a direction perpendicular to the diffusing panel by disposing, on the side of a front surface of the transparent panel, a transparent sheet which has protrusions having a saw-tooth-like sectional shape formed on one surface thereof.

Abstract: A transparent member having a multiplicity of prism-like convex portions which are aligned in parallel to each other and formed on at least one of surfaces of the member; the member is used to be disposed between a light emitting surface side of a surface light source device and a liquid crystal display device; and by using the member, it is possible to illuminate the liquid crystal display device in a bright and uniform manner and to prevent that any stripe pattern is appeared.