Patents by Inventor Kazue Watanabe

Kazue Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9868765
    Abstract: A method has been developed to efficiently proliferate and culture a CTL specific to WT1 peptides under limiting dilution conditions. Utilizing this method, CTLs capable of recognizing both a state where a wildtype WT1 specific peptide is presented by HLA-A*24:02 and a state where a mutant WT1 specific peptide is presented by HLA-A*24:02 have been successfully obtained.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: January 16, 2018
    Assignee: MEDICAL & BIOLOGICAL LABORATORIES CO., LTD.
    Inventors: Kazue Watanabe, Shingo Toji
  • Publication number: 20140212888
    Abstract: A method has been developed to efficiently proliferate and culture a CTL specific to WT1 peptides under limiting dilution conditions. Utilizing this method, CTLs capable of recognizing both a state where a wildtype WT1 specific peptide is presented by HLA-A*24:02 and a state where a mutant WT1 specific peptide is presented by HLA-A*24:02 have been successfully obtained.
    Type: Application
    Filed: August 28, 2013
    Publication date: July 31, 2014
    Applicant: Medical & Biological Laboratories Co., Ltd.
    Inventors: Kazue WATANABE, Shingo TOJI
  • Patent number: 8580925
    Abstract: [PROBLEMS] To provide examination methods and reagents able to detect efficiently cancer patients and patients at high risk of cancer. [MEANS FOR SOLVING PROBLEMS] Significant differences in the distribution of GlcNAc-6-sulfotransferase isozymes, sulfation enzymes of sugar residues, between non-carcinoma tissues and carcinoma tissues or adenoma tissues were discovered. The discovery is evidently applicable to detect carcinomas and adenomas (except colorectal carcinomas and colorectal adenomas) specifically by assaying a certain range of GlcNAc-6-sulfated sugar residue groups in tissues of patients and in fecal samples. Examination of carcinomas and adenomas is possible by the use of antibodies reacting specifically with GlcNAc-6-sulfated sugar residues specifically synthesized by enzymes present in carcinoma and adenoma tissues.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: November 12, 2013
    Assignees: Japan Science and Technology Agency, Local Government of Aichi Prefecture, Wako Pure Chemical Industries, Ltd.
    Inventors: Reiji Kannagi, Mineko Izawa, Naoko Kimura, Shunsuke Kurei, Kazue Watanabe
  • Publication number: 20080096234
    Abstract: [PROBLEMS] To provide examination methods and reagents able to detect efficiently cancer patients and patients at high risk of cancer. [MEANS FOR SOLVING PROBLEMS] Significant differences in the distribution of GlcNAc-6-sulfotransferase isozymes, sulfation enzymes of sugar residues, between non-carcinoma tissues and carcinoma tissues or adenoma tissues were discovered. The discovery is evidently applicable to detect carcinomas and adenomas (except colorectal carcinomas and colorectal adenomas) specifically by assaying a certain range of GlcNAc-6-sulfated sugar residue groups in tissues of patients and in fecal samples. Examination of carcinomas and adenomas is possible by the use of antibodies reacting specifically with GlcNAc-6-sulfated sugar residues specifically synthesized by enzymes present in carcinoma and adenoma tissues.
    Type: Application
    Filed: December 15, 2005
    Publication date: April 24, 2008
    Inventors: Reiji Kannagi, Mineko Izawa, Naoko Kimura, Shunsuke Kurei, Kazue Watanabe
  • Patent number: 7335237
    Abstract: A method for forming a desired textile printing pattern by allowing a fiber sheet to absorb a dye ink by the use of, for example, the ink-jet system, which comprises allowing a pre-treating fluid containing an aqueous emulsion having a solid component comprising an ethylene-vinyl acetate copolymer and a vinyl acetate-acrylic monomer copolymer and a fixing agent for the dye to soak into the fiber sheet, followed by drying, and then subjecting the resulting fiber sheet to a textile printing with the dye ink.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: February 26, 2008
    Assignee: Denenchofu Roman Co., Ltd.
    Inventor: Kazue Watanabe
  • Publication number: 20060241238
    Abstract: A water-based coloring composition and a water-based coating composition with each of which the number of operation steps in dyeing, printing, painting, coating or the like can be significantly reduced. The compositions enable functional compounds to be satisfactorily fixed to the substrate to be processed, and attain satisfactory fastness. The compositions do not impair the feeling of the substrate. The water-based coating composition is obtained by mixing an aqueous-emulsion-type acrylic pressure-sensitive adhesive with a cationic water-soluble polymer. The coloring composition, which is for use in dyeing, printing, painting, or coating, is obtained by mixing an aqueous-emulsion-type acrylic pressure-sensitive adhesive with a cationic water-soluble polymer and then mixing the mixture with functional compounds such as a dye, pigment, drug, deodorant, perfume, etc.
    Type: Application
    Filed: March 26, 2004
    Publication date: October 26, 2006
    Inventor: Kazue Watanabe
  • Publication number: 20060234075
    Abstract: An ink-accepting layer forming material is disclosed which is applied in advance to an ink-accepting surface of an object that is to be colored with an ink containing an anionic coloring material. The ink-accepting layer forming material comprises a weak acidic acrylic aqueous emulsion adhesive obtained by copolymerizing one or more (meth)acrylates having an alkyl group with 4-12 carbon atoms and a vinyl monomer, a water-soluble cationic polymer, and an aqueous medium. The acrylic aqueous emulsion adhesive has a viscosity of 4,000-20,000 mPa.s/30° C. when it is in an emulsion state with about 50% solid content, and a dried film of the acrylic aqueous emulsion adhesive has a glass transition temperature within the range from ?10 to ?50° C.
    Type: Application
    Filed: June 24, 2004
    Publication date: October 19, 2006
    Inventor: Kazue Watanabe
  • Publication number: 20040263598
    Abstract: A method for forming a desired textile printing pattern by allowing a fiber sheet to absorb a dye ink by the use of, for example, the ink-jet system, which comprises allowing a pre-treating fluid containing an aqueous emulsion having a solid component comprising an ethylene-vinyl acetate copolymer and a vinyl acetate-acrylic monomer copolymer and a fixing agent for the dye to soak into the fiber sheet, followed by drying, and then subjecting the resulting fiber sheet to a textile printing with the dye ink.
    Type: Application
    Filed: August 12, 2004
    Publication date: December 30, 2004
    Inventor: Kazue Watanabe
  • Patent number: 6692812
    Abstract: A multilayer sheet structure (10) comprises a front sheet (11), a net-like backing sheet (12), and sewing threads (14) for partially joining the front sheet with the backing sheet so as to form bag portions (13) between the front and backing sheets. Paddings (15) such as cotton, wool or the like can be stuffed through net clearances of the backing sheet into bag portions surrounded with sewing threads to form bulges (11b) at desired locations on the front surface of the front sheet. Thus, a quilted multilayer sheet structure (17) having bulges on the front surface thereof can be easily produced.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: February 17, 2004
    Inventor: Kazue Watanabe
  • Publication number: 20030136501
    Abstract: After an aqueous emulsion of a non-tacky or weakly tacky acrylic copolymer 4 has been infiltrate into a moisture-permeable sheet material 2 throughout almost the entire range in its thickness direction, the sheet material is dried while keeping one side of the sheet material in close contact with a non-moisture-absorptive protection sheet 3 having a smooth surface. Then a transparent coating film 8 having a smooth surface and consisting of the dried non-tacky or weakly tacky acrylic copolymer 4 is formed on the one side of the sheet material by stripping the protection sheet from the one side of the sheet material.
    Type: Application
    Filed: March 1, 2002
    Publication date: July 24, 2003
    Inventor: Kazue Watanabe
  • Patent number: 6403695
    Abstract: Novel carbon blacks having a CTAB of from 65 m2/g to 85 m2/g, a DBP of from 130 cc/100 g to 160 cc/100 g, a CTAB/I2 No. ratio of from 1.15 to 1.35, a &Dgr;DPB of from 20 cc/100 g to 40 cc/100 g, a Tint value of from 85 to 100, a Dmode of from 115 nm to 135 nm and a &Dgr;D50/Dmode ratio of from 0.65 to 0.90. Also disclosed are novel rubber compositions, incorporating the carbon blacks, having increased abrasion resistance and lower hysteresis.
    Type: Grant
    Filed: December 2, 1993
    Date of Patent: June 11, 2002
    Assignee: Cabot Corporation
    Inventors: Mizuo Soeda, Akimasa Arita, Takeo Ito, Kazue Watanabe
  • Patent number: 6228928
    Abstract: New carbon blacks that when incorporated into rubber compositions impart increased abrasion resistance and lower hysteresis. Also disclosed are rubber composition incorporating the novel carbon blacks, which have nitrogen surface area of at least 100, a CDBP of at least 105, a tint of 90-140 and a delta D50/Dmode ratio of 0.6-0.76.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: May 8, 2001
    Assignee: Cabot Corporation
    Inventors: Mizuo Soeda, Yoichi Yuza, Takeo Ito, Kazue Watanabe, Ted W. Bush, Martin Green, John M. Branan, Jr.