Patents by Inventor Kazufumi KAWABATA

Kazufumi KAWABATA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11261450
    Abstract: Provided is a recombinant cell that produces isoprene or terpene, wherein the recombinant cell includes an ability to synthesize isopentenyl diphosphate through a mevalonate pathway (MVA pathway), wherein the recombinant cell lacks an ability to synthesize isopentenyl diphosphate through an endogenous non-mevalonate pathway (MEP pathway), wherein the recombinant cell includes an isoprene synthase gene or a terpene synthase gene as a foreign gene, and wherein the recombinant cell produces, with the expression of the foreign gene, isoprene or terpene having 10, 15, 20, 30, or 40 carbon atoms. The mevalonate pathway is preferably an exogenous mevalonate pathway.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: March 1, 2022
    Assignee: SEKISUI CHEMICAL CO., LTD.
    Inventors: Kana Matsushima, Masahiro Furutani, Kazufumi Kawabata
  • Publication number: 20190352647
    Abstract: Provided is a recombinant cell that produces isoprene or terpene, wherein the recombinant cell includes an ability to synthesize isopentenyl diphosphate through a mevalonate pathway (MVA pathway), wherein the recombinant cell lacks an ability to synthesize isopentenyl diphosphate through an endogenous non-mevalonate pathway (MEP pathway), wherein the recombinant cell includes an isoprene synthase gene or a terpene synthase gene as a foreign gene, and wherein the recombinant cell produces, with the expression of the foreign gene, isoprene or terpene having 10, 15, 20, 30, or 40 carbon atoms. The mevalonate pathway is preferably an exogenous mevalonate pathway.
    Type: Application
    Filed: February 14, 2018
    Publication date: November 21, 2019
    Applicant: SEKISUI CHEMICAL CO., LTD.
    Inventors: Kana MATSUSHIMA, Masahiro FURUTANI, Kazufumi KAWABATA
  • Publication number: 20190309328
    Abstract: To provide a recombinant cell being an anaerobic archaeon, including a gene encoding isoprene synthase, a gene encoding monoterpene synthase, a gene encoding sesquiterpene synthase, a gene encoding diterpene synthase, a gene encoding squalene synthase, or a gene encoding phytoene synthase as a first foreign gene, wherein the first foreign gene is expressed, and the recombinant cell is capable of producing isoprene or terpene having 10, 15, 20, 30, or 40 carbon atoms.
    Type: Application
    Filed: October 25, 2017
    Publication date: October 10, 2019
    Applicant: SEKISUI CHEMICAL CO., LTD.
    Inventors: Masahiro FURUTANI, Kana MATSUSHIMA, Kazufumi KAWABATA
  • Publication number: 20190233854
    Abstract: Provided is a modified obligately anaerobic acetogen in which activity of at least one enzyme selected from the group consisting of a restriction enzyme, a modification enzyme, and a recognition enzyme constituting a type I restriction modification system enzyme is deleted or suppressed. Preferably, the activity of at least the restriction enzyme is deleted or suppressed. The obligately anaerobic acetogen is preferably a Clostridium bacterium or a Moorella bacterium, and particularly preferably Clostridium ljungdahlii.
    Type: Application
    Filed: September 5, 2017
    Publication date: August 1, 2019
    Applicant: SEKISUI CHEMICAL CO., LTD.
    Inventors: Kana MATSUSHIMA, Masahiro FURUTANI, Kazufumi KAWABATA
  • Publication number: 20180334657
    Abstract: A recombinant cell having a function of synthesizing acetyl-CoA from methyltetrahydrofolate, carbon monoxide, and CoA, including: a gene that expresses an exogenous NAD(P)H consumption pathway, the gene being expressed in the recombinant cell, wherein expression in at least one of endogenous NAD(P)H consumption pathways of the recombinant cell is down-regulated, and the endogenous NAD(P)H consumption pathway is different from the exogenous NAD(P)H consumption pathway, and the recombinant cell produces an organic compound having 4 or more carbon atoms from at least one selected from the group consisting of carbon monoxide and carbon dioxide via the exogenous NAD(P)H consumption pathway.
    Type: Application
    Filed: November 30, 2015
    Publication date: November 22, 2018
    Applicant: SEKISUI CHEMICAL CO., LTD.
    Inventors: Masahiro FURUTANI, Norihide NISHIYAMA, Kazufumi KAWABATA
  • Publication number: 20180023098
    Abstract: Provided is a nucleic acid encoding a fusion protein, the fusion protein including a first protein selected from the group consisting of isoprene synthase and cyclic terpene synthase, and a FKBP family protein linked to the first protein. Provided is a fusion protein encoded by the nucleic acid. Provided is a recombinant cell including the nucleic acid and expressing the fusion protein. Further provided is a recombinant cell including a first nucleic acid encoding the first protein and a second nucleic acid encoding the FKBP family protein, and expressing the first protein and the FKBP family protein. As a host cell, a syngas-assimilating bacterium or a methanol assimilating bacterium can be used.
    Type: Application
    Filed: February 10, 2016
    Publication date: January 25, 2018
    Applicant: SEKISUI CHEMICAL CO., LTD.
    Inventors: Masahiro FURUTANI, Kazufumi KAWABATA, Norihide NISHIYAMA