Abstract: An object of the present invention is to provide a separation substrate having a high megakaryocyte blocking rate and a high platelet permeation rate, and a cell separation filter and a method for producing a platelet which use the same. The separation substrate of the present invention is a separation substrate including non-woven fabric for separating a platelet from a cell suspension containing a megakaryocyte and the platelet, in which an average pore diameter of the separation substrate is 2.0 ?m to 15.0 ?m, and a thickness of the separation substrate is 10 ?m to 500 ?m.

Abstract: A nonwoven fabric is formed of fibers of 0.10 ?m or more and 5.00 ?m or less. The nonwoven fabric includes a coarse layer portion and a dense layer portion. In the coarse layer portion, a void volume Pc is at least 90% and an average pore diameter Dc is in a range of 0.5 ?m or more and 50 ?m or less. In the dense layer portion, a void volume Pd is at least 70% and a relative standard deviation of pore diameter distribution is 20% or less.

Abstract: There is provided a liquid filter having a small pressure loss and a manufacturing method for a liquid filter. The liquid filter is a liquid filter that is composed of a nonwoven fabric formed of fibers containing a water-insoluble polymer and a hydrophilizing agent. In the nonwoven fabric, a fiber density continuously changes in a film thickness direction, a fiber density difference is present in the film thickness direction, the fiber density of one surface of the nonwoven fabric in the film thickness direction is maximal, and the fiber density of the other surface of the nonwoven fabric in the film thickness direction is minimal.

Abstract: There are provide a cell separation filter with which cells can be separated without damage and can suppress adsorption, a filtering device, and a manufacturing method for a cell separation filter. The cell separation filter is composed of a nonwoven fabric that is formed of fibers containing a water-insoluble polymer and a hydrophilizing agent and has a fiber density difference in the film thickness direction. The nonwoven fabric has an average through-hole diameter of 2.0 ?m or more and less than 10.0 ?m, a void ratio of 75% or more and 98% or less, a film thickness of 100 ?m or more, and a critical wet surface tension of 72 mN/m or more.

Abstract: An object of the present invention is to provide a separation substrate having a high megakaryocyte blocking rate and a high platelet permeation rate, and a cell separation filter and a method for producing a platelet which use the same. The separation substrate of the present invention is a separation substrate including non-woven fabric for separating a platelet from a cell suspension containing a megakaryocyte and the platelet, in which an average pore diameter of the separation substrate is 2.0 ?m to 15.0 ?m, and a thickness of the separation substrate is 10 ?m to 500 ?m.

Abstract: A laminate, including at least a resin film and a pressure sensitive adhesive layer provided on one surface of the resin film, in which the resin film in the laminated state has a surface roughness Sa equal to or lower than 30 nm that is measured in a visual field of 4 mm×5 mm within a surface opposite to the surface having the pressure sensitive adhesive layer, a thickness of the pressure sensitive adhesive layer is equal to or smaller than 100 ?m, and a maximum value of a loss tangent of the pressure sensitive adhesive layer at a frequency of 1 Hz is found in a temperature range of 0° C. to ?40° C. and is equal to or greater than 1.3.

Abstract: A dope including a polymer and a solvent is prepared. The dope is casted from a casting die (43) to a casting belt (46) with forming a casting bead (100), to form a casting film (69). The decompression chamber (68) is provided behind the casting bead (100). An area including the casting die (43) and the decompression chamber (68) is partitioned as a casting section (105) from other sections by a first partition (102) and a second partition (103). A volume of the casting section (105) is set in a range of 0.80 m3 to 300.00 m3. Inside the casting section (105) is decompressed by a decompression chamber (68) while a fluctuation of air pressure is less than 2.00 Pa. A wind shielding member 101 is provided between the casting die (43) and the decompression chamber (68), to shield wind from behind the casting bead (100).

Abstract: A dope is discharged from a casting die toward a belt to form a film-like material above the belt. Thereby a range near the film-like materials is decompressed by first and second decompression chambers. A pipe connecting each decompression chamber to a pressure controller has an inner diameter from 70 mm to 700 mm, and a length of the pipe is at most 30 m. Further the pipe is provided with a first expansion silencer of expansion silencer and a second expansion silencer of resonance silencer, and a sectional dimension ratio of the first expansion silencer to the pipe is from 5 to 500. Thus a pressure fluctuation in the second decompression chamber and the pipe is reduced and the film-like material becomes uniform. Thus the obtained film has no thickness unevenness, and used for producing a polarizing filter excellent in optical properties and a liquid crystal display.

Abstract: A dope is discharged from a casting die toward a belt to form a film-like material above the belt. Thereby a range near the film-like materials is decompressed by first and second decompression chambers. A pipe connecting each decompression chamber to a pressure controller has an inner diameter from 70 mm to 700 mm, and a length of the pipe is at most 30 m. Further the pipe is provided with a first expansion silencer of expansion silencer and a second expansion silencer of resonance silencer, and a sectional dimension ratio of the first expansion silencer to the pipe is from 5 to 500. Thus a pressure fluctuation in the second decompression chamber and the pipe is reduced and the film-like material becomes uniform. Thus the obtained film has no thickness unevenness, and used for producing a polarizing filter excellent in optical properties and a liquid crystal display.

Abstract: A cope containing TAC is cast from a casting die onto a belt such that a film after the drying may have a thickness at 40 &mgr;m. A solvent of the dope solution on the belt evaporates, and thus a gel-like film may be formed. The peeling force of the gel-like film becomes to the maximum when the weight percentage of the remaining solvent in the gel-like film is 25 wt. %. In order to reduce the generation of mura or unevenness of the thickness, the gel-like film is peeled from a belt with a support of a peeling roller, when the weight percentage of the remaining solvent is at most 20 wt. %. The peeled gel-like film is dried in a tenter dryer and a casting chamber to be a film. After cooled in a cooling chamber, the film is wound by a winding device.