Abstract: The purpose of the present disclosure is to provide a defect inspection device with which it is possible to suppress variation in an output signal occurring when an imaging operation condition for an image sensor is changed. The defect inspection device according to the present disclosure comprises a detector that outputs a detection signal for signal light generated by irradiating a sample with light. The detector is controlled so that a first operation state of the detector in a first signal acquisition condition and a second operation state of the detector in a second signal acquisition condition are the same.

Abstract: Provided is a drug useful for photoimmunotherapy. Specifically, provided is a conjugate including an antibody molecule, a particle having an average particle diameter of 100 nm or less, and a photosensitive portion. In the conjugate, the particle having an average particle diameter of 100 nm or less is linked to the antibody molecule, and at least one of the antibody molecule or the particle is bound to the photosensitive portion. The photosensitive portion is a portion showing increase of hydrophobicity when irradiated with a light beam having a wavelength of from 500 nm to 900 nm or a portion containing a phthalocyanine skeleton.

Abstract: An object is to provide a novel therapeutic strategy that solves the problems involved in antibody drug conjugates (ADCs), and that can provide high therapeutic effects. Provided is a photodynamic pharmacotherapy using a target-specific conjugate containing a molecule specifically bindable to a target molecule, a drug, and a substance sensitive to near-infrared light, wherein the drug and the substance sensitive to near-infrared light are linked to the specifically bindable molecule.

Abstract: It is shown that CD25-targeted near-infrared photo-immunotherapy causes a unique, rapid and spatially selective depletion of Tregs leading to regression of the treated tumor and inducing systemic immunologic responses in untreated tumors. Based on these observations, provided are compositions and methods of killing immune suppressor cells, for example to treat cancer. Reducing the number of suppressor cells in a subject can remove suppression of effector T cells, for example, to treat cancer using the subject's own immune system. In particular examples, the method includes contacting suppressor cells having a suppressor cell surface protein with an antibody-IR700 molecule, wherein the antibody specifically binds to the suppressor cell surface protein, and in some examples the antibody does not have a functional Fc region. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm, for example at a dose of at least 4 J cm?2.

Abstract: A method for forming a multilayer coated film on an object includes steps (1) to (3) below. A first colored coating material is applied to the object, thereby forming a first colored coated film (step (1)). The first colored coating material includes an iron-oxide-coated aluminum pigment and a quinacridone pigment and has a light reflectance property at specific wavelengths. A second colored coating material is applied to the first colored coated film, thereby forming a second colored coated film (step (2)). The second colored coating material includes a perylene pigment and has a specific hue. A clear coating material is applied to the second colored coated film (step (3)). A color difference ?E between the first colored coated film and the multilayer coated film is in a range of 20 to 30.

Abstract: It is shown that CD25-targeted near-infrared photo-immunotherapy causes a unique, rapid and spatially selective depletion of Tregs leading to regression of the treated tumor and inducing systemic immunologic responses in untreated tumors. Based on these observations, provided are compositions and methods of killing immune suppressor cells, for example to treat cancer. Reducing the number of suppressor cells in a subject can remove suppression of effector T cells, for example, to treat cancer using the subject's own immune system. In particular examples, the method includes contacting suppressor cells having a suppressor cell surface protein with an antibody-IR700 molecule, wherein the antibody specifically binds to the suppressor cell surface protein, and in some examples the antibody does not have a functional Fc region. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm, for example at a dose of at least 4 J cm?2.

Abstract: An uninterruptible power supply apparatus includes a cooler cooling a converter/chopper circuit and a cooler cooling a PWM inverter. The converter/chopper circuit and the cooler make up one integrated unit. Accordingly, a smaller apparatus can be achieved, compared with a conventional apparatus in which a cooler is provided for each of a converter and a chopper.

Abstract: An uninterruptible power supply apparatus includes a cooler cooling a converter/chopper circuit and a cooler cooling a PWM inverter. The converter/chopper circuit and the cooler make up one integrated unit. Accordingly, a smaller apparatus can be achieved, compared with a conventional apparatus in which a cooler is provided for each of a converter and a chopper.

Abstract: An uninterruptible power supply apparatus includes a cooler cooling a converter/chopper circuit and a cooler cooling a PWM inverter. The converter/chopper circuit and the cooler make up one integrated unit. Accordingly, a smaller apparatus can be achieved, compared with a conventional apparatus in which a cooler is provided for each of a converter and a chopper.

Abstract: A method for forming a multilayer coated film on an object includes steps (1) to (3) below. A first colored coating material is applied to the object, thereby forming a first colored coated film (step (1)). The first colored coating material includes an iron-oxide-coated aluminum pigment and a quinacridone pigment and has a light reflectance property at specific wavelengths. A second colored coating material is applied to the first colored coated film, thereby forming a second colored coated film (step (2)). The second colored coating material includes a perylene pigment and has a specific hue. A clear coating material is applied to the second colored coated film (step (3)). A color difference ?E between the first colored coated film and the multilayer coated film is in a range of 20 to 30.

Abstract: A controller and indoor unit introducing outdoor air and/or return air from an air conditioning control target, and discharging introduced air to the air conditioning control target as supply air. The indoor unit includes a first space including an outdoor air introducing unit introducing outdoor air, a cooler, and a second space including a return air introducing unit introducing return air from the air conditioning control target. The controller, after determining air conditioning control on the air conditioning control target is necessary, introduces the outdoor air to the first space through the outdoor air introducing unit, subjecting such to cooling by the cooler and/or dehumidification to result in processed outdoor air, and introduces the return air to the second space through the return air introducing unit, where the processed outdoor air is mixed with the return air and supplied to the air conditioning control target as the supply air.

Abstract: A control unit of an uninterruptible power supply device includes a PWM circuit generating a plurality of PWM signals controlling a plurality of IGBT elements of a power conversion unit; a plurality of output terminals for supplying the plurality of PWM signals to the plurality of IGBTs; and a switching circuit arranging the plurality of PWM signals in order in accordance with the type of the uninterruptible power supply device and supplying the PWM signals to the plurality of output terminals. Accordingly, the control unit can be shared among a plurality of types of uninterruptible power supply devices.

Abstract: In this uninterruptible power supply apparatus, even after electric power supply to a load stops due to prolonged power failure time, the operation of an inverter is continued, a DC power supply voltage is generated based on an output of the inverter, and a control circuit is driven by the DC power supply voltage. Therefore, when electric power supply from a commercial AC power supply is resumed during the stop of electric power supply to the load, electric power supply to the load is automatically resumed by the control circuit.

Abstract: In an uninterruptible power supply system, control sections of three uninterruptible power supply units are connected to one another by communication cables to configure one integrated control unit. The integrated control unit brings three switches into conduction if a bias feeding mode is selected by one arbitrary operation section and brings three switches into conduction if an inverter feeding mode is selected. Therefore, there is no need to separately provide an operation section and a control section for operating and controlling all of the uninterruptible power supply units.

Abstract: A power conversion apparatus includes an inverter for converting DC power to AC power for supply to a load, a converter for converting AC power from an AC power supply to DC power for supply to the inverter, a DC voltage converter for converting a voltage value of power stored in a storage battery to supply DC power from the storage battery to the inverter when power supply from the AC power supply is faulty, and a filter including a reactor and a capacitor, for removing harmonics generated by the inverter. The inverter includes a three-level circuit which is a multi-level circuit.

Abstract: A power conversion system includes n (n being an integer of 2 or more) power conversion devices (P1 to P4) connected in parallel to a load (4); and a communication line (2) connected to the n power conversion devices (P1 to P4). Each of power conversion devices includes a communication circuit (10) which transmits a load current value detected by a current sensor (37) to each of other (n?1) power conversion devices through the communication line (2), and receives (n?1) load current values transmitted through the communication line (2) from other (n?1) power conversion devices; and an operation circuit (11) calculating a shared current and a cross current of the corresponding power conversion device based on the n load current values. Accordingly, a wiring line is prevented from becoming complicated even when the number of power conversion devices is increased.

Abstract: A controller and indoor unit introducing outdoor air and/or return air from an air conditioning control target, and discharging introduced air to the air conditioning control target as supply air. The indoor unit includes a first space including an outdoor air introducing unit introducing outdoor air, a cooler, and a second space including a return air introducing unit introducing return air from the air conditioning control target. The controller, after determining air conditioning control on the air conditioning control target is necessary, introduces the outdoor air to the first space through the outdoor air introducing unit, subjecting such to cooling by the cooler and/or dehumidification to result in processed outdoor air, and introduces the return air to the second space through the return air introducing unit, where the processed outdoor air is mixed with the return air and supplied to the air conditioning control target as the supply air.

Abstract: In an uninterruptible power supply apparatus, a common mode current flowing from nodes (N1 to N3) to a line of a ground voltage (GND) through a stray capacitance (41) of a battery (40) is limited by a common mode reactor (34), and the low-level common mode current passing through the common mode reactor (34) is caused to flow to a virtual neutral line (NL) through a common mode capacitor (37). Therefore, the level of noise caused by the common mode current can be reduced.

Abstract: In a power conversion device, reactors in an AC input filter absorbing a voltage at a carrier frequency of a PWM converter and reactors in an AC output filter absorbing a voltage at a carrier frequency of a PWM inverter include one six-leg six-phase iron core reactor. Accordingly, the device can be reduced in size when compared with a case where the reactors are composed of two four-leg six-phase iron core reactors.

Abstract: A power conversion apparatus includes an inverter for converting DC power to AC power for supply to a load, a converter for converting AC power from an AC power supply to DC power for supply to the inverter, and a DC voltage converter for converting a voltage value of power stored in a storage battery and supplying DC power from the storage battery to the inverter when power supply by the AC power supply is abnormal. The converter includes a first three-level circuit which is a multi-level circuit. Similarly, the DC voltage converter includes a second three-level circuit. A control device controls the first and second multi-level circuits to suppress potential fluctuation at a neutral point between first and second capacitors.