Patents by Inventor Kazuhiko Hanashiro

Kazuhiko Hanashiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method for agents useful in treating diabetes
    Publication number: 20050037956
    Abstract: Methods for screening agents effective against diabetes or preventing the onset of diabetes, in particular Type 2 diabetes, are provided. In one aspect of the invention, the method encompasses assaying for PAI-1 activity in the presence of a candidate agent; and correlating a decrease in PAI-1 activity relative to when the candidate agent is absent with the presence of a potential agent effective against diabetes. Alternatively, E2F activity is detected, an increase in E2F activity reflecting a decrease in PAI-1 activity. Also provided are methods for inhibiting PAI-1 activity, pharmaceutical agents and compositions.
    Type: Application
    Filed: December 13, 2002
    Publication date: February 17, 2005
    Inventors: Kazuhiko Hanashiro, Yoshikuni Nagamine