Patents by Inventor Kazuhiko Katayama
Kazuhiko Katayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11633555Abstract: A non-combustion type flavor inhaler comprising: an atomizer atomizing an aerosol source without burning; and a controller controlling a power output to the atomizer, wherein the controller is configured to start supply of a power output to the atomizer before start of a user's puffing action, and is configured to stop supply of a power output to the atomizer during a user's puffing action.Type: GrantFiled: November 28, 2017Date of Patent: April 25, 2023Assignee: JAPAN TOBACCO INC.Inventors: Kazuhiko Katayama, Akihiko Suzuki, Manabu Takeuchi, Takuma Nakano, Manabu Yamada
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Patent number: 11633557Abstract: A non-combustion type flavor inhaler comprising: an atomizer atomizing an aerosol source without burning; and a controller controlling a power output to the atomizer, wherein the controller is configured to start supply of a power output to the atomizer before start of a user's puffing action, and is configured to stop supply of a power output to the atomizer during a user's puffing action.Type: GrantFiled: February 17, 2021Date of Patent: April 25, 2023Assignee: JAPAN TOBACCO INC.Inventors: Kazuhiko Katayama, Akihiko Suzuki, Manabu Takeuchi, Takuma Nakano, Manabu Yamada
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Patent number: 11517616Abstract: The present invention addresses the issue of providing a norovirus component vaccine for subcutaneous, intradermal, percutaneous, or intramuscular administration which vaccine can readily immunize the target cells, an associated product of a molecular needle serving as an active ingredient of the vaccine, and a production method for the associated product. The invention provides a norovirus component vaccine containing, as an active ingredient, an associated product including a hexamer formed through bonding of two molecules of a trimer of a molecular needle represented by the following formula (1). W-L1-Xn—Y (1) [wherein W represents an amino acid sequence of P domain of the capsid protein of norovirus as an immunogen; L1 represents a first linker sequence having 0 to 100 amino acids; X represents an amino acid sequence represented by SEQ ID NO: 1; Y represents an amino acid sequence of a cell introduction domain; n is an integer of 1 to 3].Type: GrantFiled: October 19, 2017Date of Patent: December 6, 2022Assignees: Denka Company Limited, TOKYO INSTITUTE OF TECHNOLOGY, THE KITASATO INSTITUTE, DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASESInventors: Takafumi Ueno, Kengo Yoshikawa, Megumi Mano, Kazuhiko Katayama, Motohiro Miki, Reiko Todaka, Yoshimasa Takahashi, Taishi Onodera
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Publication number: 20220362370Abstract: An object of the present invention is to establish means for providing a component vaccine which can elicit immunity to a non-structural protein. The present inventors have found that the object can be attained by providing a component vaccine containing an associated product containing a trimer and/or a hexamer of a molecular needle to which a non-structural protein of a pathogenic virus is attached.Type: ApplicationFiled: August 26, 2020Publication date: November 17, 2022Applicants: TOKYO INSTITUTE OF TECHNOLOGY, THE KITASATO INSTITUTE, DENKA COMPANY LIMITEDInventors: Takafumi UENO, Dan Que NGUYEN, Kazuhiko KATAYAMA, Reiko TODAKA, Kei HAGA, Akihito SAWADA
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Publication number: 20220218015Abstract: Provided is an oral tobacco product in which the amount of an oral tobacco material relative to a gum molded body can be changed in accordance with feelings and preferences of a user. The oral tobacco product includes an oral tobacco material that contains a tobacco raw material, a gum molded body that contains a gum base and that does not contain a tobacco raw material, and a packaging material that houses each of the oral tobacco material and the gum molded body in a state of being separated from each other.Type: ApplicationFiled: April 1, 2022Publication date: July 14, 2022Applicant: JAPAN TOBACCO INC.Inventors: Yutaka KAIHATSU, Kazuhiko KATAYAMA
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Patent number: 11299750Abstract: An object of the present invention is to solve problems in terms of stagnation of research on norovirus by providing a cultured transgenic cell or a transgenic animal in which murine norovirus (MNV) can be grown across the barrier of host specificity in mammalian cells, and providing a screening method that uses the cultured transgenic cell or the transgenic animal. The present inventors have found that MNV infection is determined in a cultured transgenic mammalian cell or a mammal possessing the cultured transgenic mammalian cell as its own cell, the cultured transgenic mammalian cell containing one or more species selected from the entirety or a portion of the murine CD300F gene and/or a CD300 family gene having an extracellular domain nucleotide sequence similar to that of the murine CD300F gene. The present inventors have solved the aforementioned problems by providing, for example, a norovirus-related drug screening method on the basis of this finding.Type: GrantFiled: February 1, 2017Date of Patent: April 12, 2022Assignees: DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES, Denka Company Limited, NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGYInventors: Kei Haga, Akira Fujimoto, Reiko Todaka, Kazuhiko Katayama, Akira Nakanishi, Motohiro Miki, Sakari Sekine, Hiroshi Otsuka, Shigetaka Mimori
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Publication number: 20220062315Abstract: An object of the present invention is to provide an anti-human norovirus agent which can inhibit infection with and proliferation of human norovirus. The present inventors have found that the object can be attained through provision of an anti-human norovirus agent comprising, as an active ingredient, a fucose analog having an inhibitory action on glycosylation by fucosyltransferase (FUT). Examples of the active ingredient include a fucose analog represented by formula (III) or (IV) or a salt thereof. [In the formulas, each of formula (III) and formula (IV) represents an ?-anomer or a ?-anomer; each of R4, R3, and R4 is —OH or -OAc; R2 is a halogen atom, —OH, or -OAc; and R5 is —CH3, —C?CH, —C?CCH3, or —CH2C?CH.Type: ApplicationFiled: December 27, 2019Publication date: March 3, 2022Applicants: KEIO UNIVERSITY, THE KITASATO INSTITUTEInventors: Kazuhiko KATAYAMA, Akira FUJIMOTO, Kei HAGA, Reiko TODAKA, Toshiro SATO
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Patent number: 11160304Abstract: A smokeless flavor inhalator includes a tobacco material as a flavor generator, and a heater for heating the tobacco material to allow flavor components to be released from the tobacco material while preventing smoke from being generated from the tobacco material. The heater has a carbon heat source and a cooling element. The carbon heat source and the cooling element cooperatively keep the heating temperature of the tobacco material at a temperature of 50 to 200° C.Type: GrantFiled: July 18, 2018Date of Patent: November 2, 2021Assignee: JAPAN TOBACCO INC.Inventors: Yasuhiro Shinozaki, Kazuhiko Katayama, Takeshi Akiyama, Yoshiaki Ishikawa, Manabu Yamada
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Publication number: 20210299240Abstract: The present invention addresses the issue of providing a norovirus component vaccine for subcutaneous, intradermal, percutaneous, or intramuscular administration which vaccine can readily immunize the target cells, an associated product of a molecular needle serving as an active ingredient of the vaccine, and a production method for the associated product. The invention provides a norovirus component vaccine containing, as an active ingredient, an associated product including a hexamer formed through bonding of two molecules of a trimer of a molecular needle represented by the following formula (1). W-L1-Xn—Y (1) [wherein W represents an amino acid sequence of P domain of the capsid protein of norovirus as an immunogen; L1 represents a first linker sequence having 0 to 100 amino acids; X represents an amino acid sequence represented by SEQ ID NO: 1; Y represents an amino acid sequence of a cell introduction domain; n is an integer of 1 to 3].Type: ApplicationFiled: October 19, 2017Publication date: September 30, 2021Applicants: DENKA COMPANY LIMITED, TOKYO INSTITUTE OF TECHNOLOGY, THE KITASATO INSTITUTE, JAPAN AS REPRESENTED BY DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASESInventors: Takafumi UENO, Kengo YOSHIKAWA, Megumi MANO, Kazuhiko KATAYAMA, Motohiro MIKI, Reiko TODAKA, Yoshimasa TAKAHASHI, Taishi ONODERA
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Publication number: 20210170124Abstract: A non-combustion type flavor inhaler comprising: an atomizer atomizing an aerosol source without burning; and a controller controlling a power output to the atomizer, wherein the controller is configured to start supply of a power output to the atomizer before start of a user's puffing action, and is configured to stop supply of a power output to the atomizer during a user's puffing action.Type: ApplicationFiled: February 17, 2021Publication date: June 10, 2021Applicant: JAPAN TOBACCO INC.Inventors: Kazuhiko KATAYAMA, Akihiko SUZUKI, Manabu TAKEUCHI, Takuma NAKANO, Manabu YAMADA
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Publication number: 20210170123Abstract: A non-combustion type flavor inhaler comprising: an atomizer atomizing an aerosol source without burning; and a controller controlling a power output to the atomizer, wherein the controller is configured to start supply of a power output to the atomizer before start of a user's puffing action, and is configured to stop supply of a power output to the atomizer during a user's puffing action.Type: ApplicationFiled: February 17, 2021Publication date: June 10, 2021Applicant: JAPAN TOBACCO INC.Inventors: Kazuhiko KATAYAMA, Akihiko SUZUKI, Manabu TAKEUCHI, Takuma NAKANO, Manabu YAMADA
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Publication number: 20210090255Abstract: A recording medium stores therein a program for causing a computer to execute processing includes: acquiring images of N or less each including teeth adjacent to each other; arranging and displaying, in N image display areas capable of displaying the images in association with an arrangement of teeth, each of the images, in association with each of the N image display areas, a selection area for selecting presence or absence of an image and input areas for inputting information indicating a condition of each tooth included in an image displayed in each of the N image display areas; receiving a selection content in the selection area or input contents in the input areas or combination of the selection content and the input contents; and generating learning information in which a condition of each of the teeth and an image of each of the teeth are associated with each other.Type: ApplicationFiled: December 8, 2020Publication date: March 25, 2021Applicant: FUJITSU LIMITEDInventors: Takashi Kumagai, Tadashi Fujioka, Chikashi Kigure, Kazuhiko Katayama, Yuji Deki, Shirin Aoki, Fumiyuki Takehisa, Tsugumasa Yamamoto, Wataru Oura
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Patent number: 10668233Abstract: A method of manufacturing a flavor cartridge for a flavor inhalator, the method comprising the steps of filling a predetermined amount of a flavor generating material capable of emitting a flavor component in a frame compressing the flavor generating material in the frame by applying pressure thereto by a pusher and fixing a lid to the frame, wherein the flavor generating material contains a tobacco material obtained by shredding or pulverizing tobacco leaf, and the lid has air permeability.Type: GrantFiled: May 16, 2017Date of Patent: June 2, 2020Assignee: JAPAN TOBACCO INC.Inventors: Hirofumi Matsumoto, Takeshi Shinkawa, Atsuro Yamada, Kazuhiko Katayama, Manabu Yamada, Tomoichi Watanabe
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Publication number: 20200087617Abstract: A 2D organoid for infection and growth culture of human diarrhea virus, obtained by: (1) obtaining a 3D organoid by three-dimensionally culturing a human intestinal epithelial stem cell, a human intestinal epithelial cell, or a tissue containing at least any of those cells on an extracellular matrix; and (2) dispersing the 3D organoid to prepare a single cell, and monolayer-culturing the single cell on an extracellular matrix to obtain the 2D organoid having a monolayer structure in which epithelial cells contain differentiated trophoblastic cells and goblet cells and configured as human intestinal lumen having a monolayer structure.Type: ApplicationFiled: August 21, 2017Publication date: March 19, 2020Inventors: Toshiro Sato, Kazuhiko Katayama
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Patent number: 10390555Abstract: The production process comprises a step (A) in which an alkali-treated tobacco source is heated to make the tobacco source release a flavoring ingredient into a gas phase, a step (B) in which the flavoring ingredient released into the gas phase is brought into contact with a given solvent which is a liquid substance at ordinary temperature, thereby trapping the flavoring ingredient in the given solvent, and a step (C) in which the given solvent is added to a constituent element.Type: GrantFiled: October 23, 2015Date of Patent: August 27, 2019Assignee: JAPAN TOBACCO INC.Inventors: Yoshinori Fujisawa, Takuma Nakano, Kimitaka Uchii, Manabu Takeuchi, Kazuhiko Katayama, Manabu Yamada
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Publication number: 20190040415Abstract: An object of the present invention is to solve problems in terms of stagnation of research on norovirus by providing a cultured transgenic cell or a transgenic animal in which murine norovirus (MNV) can be grown across the barrier of host specificity in mammalian cells, and providing a screening method that uses the cultured transgenic cell or the transgenic animal. The present inventors have found that MNV infection is determined in a cultured transgenic mammalian cell or a mammal possessing the cultured transgenic mammalian cell as its own cell, the cultured transgenic mammalian cell containing one or more species selected from the entirety or a portion of the murine CD300F gene and/or a CD300 family gene having an extracellular domain nucleotide sequence similar to that of the murine CD300F gene. The present inventors have solved the aforementioned problems by providing, for example, a norovirus-related drug screening method on the basis of this finding.Type: ApplicationFiled: February 1, 2017Publication date: February 7, 2019Applicants: JAPAN AS REPRESENTED BY DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES, DENKA COMPANY LIMITED, NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGYInventors: Kei HAGA, Akira FUJIMOTO, Reiko TODAKA, Kazuhiko KATAYAMA, Akira NAKANISHI, Motohiro MIKI, Sakari SEKINE, Hiroshi OTSUKA, Shigetaka MIMORI
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Publication number: 20180317560Abstract: A smokeless flavor inhalator includes a tobacco material as a flavor generator, and a heater for heating the tobacco material to allow flavor components to be released from the tobacco material while preventing smoke from being generated from the tobacco material. The heater has a carbon heat source and a cooling element. The carbon heat source and the cooling element cooperatively keep the heating temperature of the tobacco material at a temperature of 50 to 200° C.Type: ApplicationFiled: July 18, 2018Publication date: November 8, 2018Applicant: JAPAN TOBACCO INC.Inventors: Yasuhiro SHINOZAKI, Kazuhiko KATAYAMA, Takeshi AKIYAMA, Yoshiaki ISHIKAWA, Manabu YAMADA
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Patent number: 10080384Abstract: A chewable oral tobacco composition (1) including a tobacco raw material for eluting a tobacco component and a gum base comprises: a first gum portion (10) including the tobacco raw material and a first gum base; and a second gum portion (20) including a second gum base. The second gum portion does not include the tobacco raw material or includes the tobacco raw material in an amount less than an amount of the tobacco raw material included in the first gum portion. A weight of the first gum base is 0.3 g or more. Wt. % of the first gum base is 50 wt. % or more when wt. % of the first gum portion is 100 wt. %. Total wt. % of the first gum base and the second gum base is 50 wt. % or less when wt. % of the oral tobacco composition is 100 wt. %.Type: GrantFiled: April 29, 2016Date of Patent: September 25, 2018Assignee: JAPAN TOBACCO INC.Inventors: Kimitaka Uchii, Kazuhiko Katayama, Takuma Nakano, Manabu Yamada
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Publication number: 20180077971Abstract: A non-combustion type flavor inhaler comprising: an atomizer atomizing an aerosol source without burning; and a controller controlling a power output to the atomizer, wherein the controller is configured to start supply of a power output to the atomizer before start of a user's puffing action, and is configured to stop supply of a power output to the atomizer during a user's puffing action.Type: ApplicationFiled: November 28, 2017Publication date: March 22, 2018Applicant: JAPAN TOBACCO INC.Inventors: Kazuhiko KATAYAMA, Akihiko SUZUKI, Manabu TAKEUCHI, Takuma NAKANO, Manabu YAMADA
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Publication number: 20170246407Abstract: A method of manufacturing a flavor cartridge for a flavor inhalator, the method comprising the steps of filling a predetermined amount of a flavor generating material capable of emitting a flavor component in a frame compressing the flavor generating material in the frame by applying pressure thereto by a pusher and fixing a lid to the frame, wherein the flavor generating material contains a tobacco material obtained by shredding or pulverizing tobacco leaf, and the lid has air permeability.Type: ApplicationFiled: May 16, 2017Publication date: August 31, 2017Applicant: JAPAN TOBACCO INC.Inventors: Hirofumi MATSUMOTO, Takeshi SHINKAWA, Atsuro YAMADA, Kazuhiko KATAYAMA, Manabu YAMADA, Tomoichi WATANABE