Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: An object is to provide a communication system in which there are no restrictions on a communicable area and it is not necessary to install communication software on a wireless device. A communication system according to the present invention is configured so that the functions of a wireless access point are separated into a front-end unit on a wireless terminal side and a back-end side on the Internet side, radio signal processing functions supporting a wireless scheme of the wireless terminal are deployed only on the back end, and only relatively simple processing functions such as E/O conversion are deployed on the front end near the wireless terminal 311.

Abstract: The present disclosure aims to make it possible to simultaneously establish communication between many freely-selected radio terminals without using a complex relay network or a plurality of radio relays. The present disclosure is a communication network system including: a plurality of optical-radio converters 521-1 to 521-n that convert a radio signal and an optical fiber radio signal into each other; and a path controller that is connected to the plurality of optical-radio converters 521-1 to 521-n through optical fiber transmission lines 531-1 to 531-n, receives input of an optical fiber radio signal transmitted from any optical-radio converter of the plurality of optical-radio converters 521-1 to 521-n from the optical fiber transmission line connected to the optical-radio converter, and outputs the optical fiber radio signal to the optical fiber transmission line connected to a set optical-radio converter of the plurality of optical-radio converters 521-1 to 521-n.

Abstract: The present disclosure aims to make it possible to simultaneously establish communication between many freely-selected radio terminals without using a complex relay network or a plurality of radio relays. The present disclosure is a communication network system including: a plurality of optical-radio converters 521-1 to 521-n that convert a radio signal and an optical fiber radio signal into each other; and a path controller that is connected to the plurality of optical-radio converters 521-1 to 521-n through optical fiber transmission lines 531-1 to 531-n, receives input of an optical fiber radio signal transmitted from any optical-radio converter of the plurality of optical-radio converters 521-1 to 521-n from the optical fiber transmission line connected to the optical-radio converter, and outputs the optical fiber radio signal to the optical fiber transmission line connected to a set optical-radio converter of the plurality of optical-radio converters 521-1 to 521-n.

Abstract: A repeater such as an Internet router device used in a communication network such as the Internet. The delay time from a device of a sender to a device of a receiver is secured. A communication system, a control circuit, a connecting means, and a computer program are also disclosed. The sending time intervals between sending to a transmission network are calculated from a target value of the transfer rate of a packet to be relayed (S202), a target value of the delay time is determined on the basis of the delay time to be secured (S205), and a reference value of the storage capacity used as a criterion for deciding discard of a packet is calculated from the delay time target value and the sending time intervals (S206). Packets are sent out at the calculated sending time intervals, and discard of a packet is judged according to a predetermined method when a packet having a storage capacity above the storage capacity reference value is received.

Abstract: An output port circuit is provided for a router apparatus which routes and transmits a received packet. Each flow is constituted by continuous packets and belongs to a bandwidth-guaranteed class or a best-effort class. A controller controls storage and reading of a packet into and from a storage unit. Upon allocating a basic volume that is a criterion of a memory size stored in the storage unit to each flow to which the packet to be transmitted belongs, the controller manages the basic volume of each flow of the packet belonging to the bandwidth-guaranteed class by individually allocating the basic volume by the memory size required by each flow, and manages the basic volume of each flow of the packets belonging to the best-effort class by collectively allocating the memory size obtained by subtracting a sum of respective basic volumes allocated to the bandwidth-guaranteed class from an entire memory size.

Abstract: An optical microscope of high stability such that problems wherein an image of a sample becomes unsharp during observation and movement (drift) of the object point (object) occurs are solved because the defocusing in the Z direction attributable to thermal expansion of the optical microscope is compensated. The optical instruments are characterized as comprising an optical system unit symmetrical to the optical axis in terms of weight and shape and a peripheral unit having a sample positioning mechanism is constituted by combining components having temperature dependences close to zero.

Abstract: This invention provides a highly stable optical microscope that prevents drift and makes it possible to record images or take measurements for several hours with accuracy in the order of nanometers. The highly stable optical microscope of this invention includes the support structure (41) that accommodates and supports components including the optical imaging system, straight tube (28) that accommodates and supports components including the optical photometric system, and support structure (7) that accommodates and supports components including the illumination system. These support structures have a hollow pyramid or conical shape with a low center of gravity. The highly stable optical microscope of this invention features the objective lenses, imaging lenses, optical imaging and photometric systems that are mounted, forming a straight line, on the supporting structures that are symmetrical about the optical axis in both shape and mass.

Abstract: The trapping force reinforcing optical system that enables optical tweezers to trap micro particles under water securely, without contact and non-invasively using a laser beam. The optics of the optical tweezers comprises an additional lens system movable along an optical axis, and a spherical aberration of a collector lens is controlled by moving the additional lens system along the optical axis.

Abstract: An optical microscope of high stability such that the image of a sample does not become obscure during observation, and no movement (drift) of an object point (object) occurs. The optical microscope is characterized by comprising vertical straight movement guide mechanisms (4 and 8) for an objective lens (6) of the microscope symmetrical to the optical axis, and fine adjustment units (10, 11 and 12) for the objective lens.

Abstract: This invention provides an optical mixer to convert coherent light into virtually incoherent light by using a hollow motor to rotate the optical mixing plate at the peripheral speed of at least 1800 times per minute relative to the laser beam diameter. This invention comprises an optical mixing plate 8 installed on the light path and a hollow motor 2 to rotate said optical mixing plate 8 at high speed, and is capable of converting the laser beams incident on said optical mixing plate 8 into virtually incoherent light.

Abstract: Optical microscopes are used to record images or take measurements for extended times of several hours. During such extended usage, the microscope moves slightly causing the object to shift or defocus (drift). This invention provides a highly stable optical microscope that prevents drift and makes it possible to record images or take measurements for several hours with accuracy in the order of nanometers. The highly stable optical microscope of this invention comprises the support structure 42 that accommodates and supports components comprising the optical imaging system, straight tube 28 that accommodates and supports components comprising the optical photometric system, and support structure 7 that accommodates and supports components comprising the illumination system. These support structures have a hollow pyramid or conical shape with a low center of gravity.

Abstract: The trapping force reinforcing optical system that enables optical tweezers to trap micro particles under water securely, without contact and non-invasively using a laser beam. The optics of the optical tweezers comprises an additional lens system movable along an optical axis, and a spherical aberration of a collector lens is controlled by moving the additional lens system along the optical axis.

Abstract: An output port circuit is provided for a router apparatus which routes and transmits a received packet. Each flow is constituted by continuous packets and belongs to a bandwidth-guaranteed class or a best-effort class. A controller controls storage and reading of a packet into and from a storage unit. Upon allocating a basic volume that is a criterion of a memory size stored in the storage unit to each flow to which the packet to be transmitted belongs, the controller manages the basic volume of each flow of the packet belonging to the bandwidth-guaranteed class by individually allocating the basic volume by the memory size required by each flow, and manages the basic volume of each flow of the packets belonging to the best-effort class by collectively allocating the memory size obtained by subtracting a sum of respective basic volumes allocated to the bandwidth-guaranteed class from an entire memory size.

Abstract: An optical microscope of high stability such that the image of a sample does not become obscure during observation, and no movement (drift) of an object point (object) occurs. The optical microscope is characterized by comprising vertical straight movement guide mechanisms (4 and 8) for an objective lens (6) of the microscope symmetrical to the optical axis, and fine adjustment means (10, 11 and 12) for the objective lens.

Abstract: An optical microscope of high stability such that problems wherein an image of a sample becomes unsharp during observation and movement (drift) of the object point (object) occurs are solved because the defocusing in the Z direction attributable to thermal expansion of the optical microscope is compensated. The optical instruments are characterized as comprising an optical system unit symmetrical to the optical axis in terms of weight and shape and a peripheral unit having a sample positioning mechanism is constituted by combining components having temperature dependences close to zero.