Abstract: A blood vessel specifying device (1) includes an image processing device (31) configured to subject an image for analysis of a target part (2) to image processing to acquire blood vessel information including positions and shapes of blood vessels included in the target part (2), an evaluation device (32) configured to use the blood vessel information to assign a point rating regarding a parameter that indicates a conformity to a particular purpose with respect to the blood vessels included in the image for analysis depending on a degree of the conformity, and a specification device (33) configured to specify conforming blood vessels conforming to the purpose from the blood vessels included in the target part (2) in accordance with rating points of the parameter.

Abstract: A blood vessel position display device (1) includes an image processing device (31) configured to subject an image for analysis of a target part (2) to image processing to acquire blood vessel information including positions and shapes of blood vessels included in the target part (2), a selection device (32) configured to choose blood vessels as conforming blood vessels in which a parameter obtained from the blood vessel information satisfies specific conditions, an image generation device (33) configured to generate a projection image including display lines at least set to have lengths corresponding to the conforming blood vessels, and a projection device (40) configured to cause the positions of the display lines to correspond to the positions of the conforming blood vessels so as to project the projection image on the target part (2).

Abstract: To provide a distribution measuring sensor system and the like having a high spatial resolution and can greatly reduce a wiring region even if many sensor units for the measurement of a contact pressure and a shear stress acting on an interface between a living body and an object are integrated. A distribution measuring sensor 10 has a configuration in which sensor units Uij which measure a shear stress in a direction of a plane and a contact pressure in a direction perpendicular to the plane are arranged at each element of a matrix M. The sensor units Uij are constituted of an upper electrode UijH common to measurement of the shear stress and the contact pressure, and a lower electrode UijL arranged below the upper electrode UijH through a pressure sensitive material 20. Each sensor unit Uij in the x axis direction arranged in the same column j of the matrix M has each upper electrode UijH connected in the column j direction in common through the connecting line Cj.

Abstract: To provide a distribution measuring sensor system and the like having a high spatial resolution and can greatly reduce a wiring region even if many sensor units for the measurement of a contact pressure and a shear stress acting on an interface between a living body and an object are integrated. A distribution measuring sensor 10 has a configuration in which sensor units Uij which measure a shear stress in a direction of a plane and a contact pressure in a direction perpendicular to the plane are arranged at each element of a matrix M. The sensor units Uij are constituted of an upper electrode UijH common to measurement of the shear stress and the contact pressure, and a lower electrode UijL arranged below the upper electrode UijH through a pressure sensitive material 20. Each sensor unit Uij in the x axis direction arranged in the same column j of the matrix M has each upper electrode UijH connected in the column j direction in common through the connecting line Cj.

Abstract: Estimation related to void formation and breakage/failure is performed through numerical simulation using dominant parameters of EM damage in a metal interconnect. The metal interconnect is divided into elements. Current density and temperature distribution is obtained using numerical analysis. Atomic flux divergence AFDgen of each element and the distribution thereof is calculated by using material property constants determined through acceleration testing. The reduction of volume per one calculation step in the simulation is found by multiplying the volume of each element, the length of time corresponding to one calculation step, and the atomic volume corresponding to the calculated AFDgen. Based on the reduced amount of volume, the thickness of each element decreases. The elements having a decrease in thickness show the fact that voids have formed.

Abstract: A new compound, which we have named Leustroducsin H, has formula (I): ##STR1## and pharmaceutically acceptable salts thereof. This compound may be prepared by hydrolysis of naturally occurring Leustroducsins and the compound may be used for the treatment or prophylaxis of thrombocytopenia.

Abstract: Rhizoxin and rhizoxin-2-ene derivatives of formula (I): ##STR1## in which: n is 1 to 25: A is an extra bond or oxygen, X is oxygen, sulfur, nitrogen or carbonyl; and R is hydrogen, carboxylic acyl having from 1 to 25 carbon atoms, alkoxycarbonyl group having from 2 to 26 carbon atoms, phosphono, alkylphosphono group in which the alkyl part has from 1 to 25 carbon atoms, dialkylphosphono group in which each alkyl part has from 1 to 25 carbon atoms, alkyl group having from 1 to 25 carbon atoms, aralkyl, cycloalkyl, heterocyclic, alkylthio group in which the alkyl part has from 1 to 25 carbon atoms, aralkylthio, or heterocyclylthio, or when X represents a nitrogen atom, R is R.sup.1 and R.sup.2, where R.sup.1 and R.sup.2 are hydrogen, alkyl, acyl, alkoxycarbonyl, phosphono, alkylphosphono or dialkylphosphono have valuable anti-tumor activity. They may be prepared by acylation of rhizoxin or rhizoxin-2-ene.

Abstract: Rhizoxin and rhizoxin-2-ene derivatives of formula ##STR1## in which: n is 1 to 25; A is an extra bond or oxygen, X is oxygen, sulfur, nitrogen or carbonyl; and R is hydrogen, carboxylic acyl having from 1 to 25 carbon atoms, alkoxycarbonyl group having from 2 to 26 carbon atoms, phosphono, alkylphosphono group in which the alkyl part has from 1 to 25 carbon atoms, dialkylphosphono group in which each alkyl part has from 1 to 25 carbon atoms, alkyl group having from 1 to 25 carbon atoms, aralkyl, cycloalkyl, heterocyclic, alkylthio group in which the alkyl part has from 1 to 25 carbon atoms, aralkylthio, or heterocyclylthio, or when X represents a nitrogen atom, R is R.sup.1 and R.sup.2, where R.sup.1 and R.sup.2 are hydrogen, alkyl, acyl, alkoxycarbonyl, phosphono, alkylphosphono or dialkylphosphono, have valuable anti-tumor activity. They may be prepared by acylation of rhizoxin or rhizoxin-2-ene.

Abstract: Compounds of formula (I): ##STR1## [in which: Y represents a group of formula ##STR2## the dotted line is a double of single bond; R.sup.1 is hydrogen, alkyl or aryl; R.sup.2 is hydrogen or halogen; R.sup.3 is alkyl or cycloalkyl; R.sup.4 is hydrogen, alkyl, hydroxy or halogen; and R.sup.6 is hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or aralkyl;]and pharmaceutically acceptable salts thereof are valuable in the treatment of cachexia. Certain of these compounds are novel.

Abstract: Compounds of formula (I): ##STR1## and pharmaceutically acceptable salts thereof are valuable in the treatment of cachexia.

Abstract: Compounds of formula (I): ##STR1## [wherein: m is 1-3; A and B are oxygen or sulfur; and one of R.sup.1 and R.sup.2 is C.sub.10 -C.sub.22 alkyl and the other is a group of formula (II). ##STR2## where: n is 2 or 3; and --NR.sup.3 R.sup.4 R.sup.5 is an amino group] and salts thereof are effective anti-cancer agents.

Abstract: Prostanoic acid derivatives having the formula ##STR1## wherein A represents a straight or branched alkylene group having from one to 5 carbon atoms, R.sup.1 represents a straight or branched alkyl group having from 4 to 10 carbon atoms and R.sup.2 represents hydrogen atom or a straight or branched alkyl group having from one to 6 carbon atoms and pharmaceutically acceptable salts thereof.The compounds are useful as oxytocic agents and agents inhibiting the secretion of gastric acid and may be prepared by oxidizing a compound having the formula ##STR2## wherein A, R.sup.1 and R.sup.2 are the same as above, R.sup.3 and R.sup.4 are the same or different and each represents a protecting group for the hydroxyl group to give a compound having the formula ##STR3## wherein A, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are the same as above, removing the hydroxyl-protecting group from the latter compound and, if appropriate, salifying the product thus obtained.