Patents by Inventor Kazuhiko Yamada

Kazuhiko Yamada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5576335
    Abstract: Urea derivatives of formula (1) ##STR1## wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of hypercholesterolemia and atherosclerosis.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: November 19, 1996
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Noriyoshi Sueda, Kazuhiko Yamada, Makoto Yanai, Katsutoshi Miura, Masato Horigome, Norio Oshida, Shigeru Hiramoto, Koichi Katasuyama, Fumihisa Nakata, Nobuhiro Kinoshita, Yoko Tsukada
  • Patent number: 5344831
    Abstract: Diazabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, alkoxyalkyl, oxoalkyl, alkoxycarbonylalkyl, alkoxycarbonyl, acyl, dialkylaminoalkyl, hydroxyalkyl, haloalkyl, cyanoalkyl, heterocycloalkyl, aryl, heteroarylalkyl or arylalkyl, the aryl group and the aryl moiety being optionally substituted by alkoxy, nitro, alkyl, amino or halo;R.sup.2 is hydrogen or alkyl;R.sup.3 and R.sup.4 may be the same or different and each is hydrogen, alkyl, alkenyl, acyl, alkoxyalkyl or arylalkyl wherein the aryl moiety is optionally substituted by alkoxy, nitro, alkyl, amino or halo;with the proviso that when R.sup.2 is hydrogen and both R.sup.3 and R.sup.4 are methyl, R.sup.1 does not represent hydrogen, alkyl, unsubstituted benzyl or dimethylaminoethyl; having 5-HT.sub.3 receptor antagonist activity.
    Type: Grant
    Filed: January 28, 1993
    Date of Patent: September 6, 1994
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Hiroaki Satoh, Haruhiko Kikuchi, Kazuhiko Yamada, Ruta Fukutomi, Masashi Suzuki, Koichiro Hagihara, Toru Hayakawa, Takeo Arai, Setsuko Mino
  • Patent number: 5250434
    Abstract: Novel bacteria identified as effective in glutamic acid production through fermentation chemistry conducted at temperatures above 42.degree. C.
    Type: Grant
    Filed: May 16, 1991
    Date of Patent: October 5, 1993
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kazuhiko Yamada, Akira Seto
  • Patent number: 4954920
    Abstract: A thin film magnetic head has a layer of soft magnetic material formed on a substrate. The layer is formed into two yoke pieces and a magnetic return path, which form a gap at ends of the yoke pieces. The opposite ends of the yoke pieces are joined to the magnetic return path by overlaying magneto-resistive pieces to which an electrical bias is applied.
    Type: Grant
    Filed: November 30, 1987
    Date of Patent: September 4, 1990
    Assignee: NEC Corporation
    Inventors: Kazuhiko Yamada, Takao Maruyama
  • Patent number: 4928779
    Abstract: A vehicle speed control device for providing constant speed traveling including a main switch circuit for enabling the constant speed traveling, a CPU coupled to the main switch circuit for providing a constant speed traveling control signal, and an actuator for activating a throttle value coupled thereto in response to the control signal output by the CPU. An electromagnetic relay coupled to the actuator inhibits the actuator in response to several signals including a signal from a timer circuit and the timer circuit provides its signal for a time after the start of the engine of the vehicle that is related to a sensed temperature in the engine.
    Type: Grant
    Filed: August 9, 1988
    Date of Patent: May 29, 1990
    Assignee: Kabushiki Kaisha Tokai Rika Denki Seisakusho
    Inventor: Kazuhiko Yamada
  • Patent number: 4925969
    Abstract: Ethyl-.beta.-benzoyacrylate is reacted with an alkali metal salt of (S)-alanine or an alkali metal salt of N.sup.6 -trifluoroacetyl-L-lysine to form the corresponding Michael addition product, and not less than an equivalent amount of acid is added after completion of the Michael addition to prevent conversion of the (S,S) form of the product to the (R,S) form.
    Type: Grant
    Filed: March 16, 1989
    Date of Patent: May 15, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satomi Takahashi, Yasuyoshi Ueda, Kazuhiko Yamada, Yukio Yamada, Takehiko Yamane, Yoshifumi Yanagita, Yoshio Shimada, Kiyoshi Watanabe, Michio Nomura, Takehisa Ohashi, Kenji Inoue
  • Patent number: 4906669
    Abstract: Anti-ulcer agents containing isoprenoid derivatives are provided. The isoprenoid derivatives are represented by the formula: ##STR1## wherein: R represents a group of formula ##STR2## In the above formula, R.sub.1, R.sub.2 and R.sub.3 may be the same or different each other and each represents a hydrogen atom, a hydroxy group, a lower alkanoyloxy group, a lower alkyl group or a lower alkoxy group, provided that two or more of them do not represent hydrogen atoms at the same time; R.sub.4 and R.sub.5 may be the same or different each other and each represents a hydrogen atom, a hydroxy group or a lower alkanoyloxy group represents the signal or the double bond between the carbon atoms; m represents 0 or 1; n represents 0 or an integer of from 1 to 9, provided that the sum of m and n is an integer of from 1 to 9.
    Type: Grant
    Filed: August 22, 1988
    Date of Patent: March 6, 1990
    Assignees: Nisshin Flour Milling Co., Ltd., Grelan Pharmaceutical Co., Ltd.
    Inventors: Kazuhiko Yamada, Yoshiyuki Tahara, Masashi Toyoda, Osamu Irino, Noriyuki Misaki
  • Patent number: 4891624
    Abstract: The detection system for obstruction to vehicle according to the invention comprises a plurality of light emitting elements disposed in the rear of a car, a modulation for emitting modulation lights from the light emitting elements, light receiving elements for receiving the reflected light that the modulation light comes in contact with an external obstruction to reflection, a detection circuit for detecting output signals of the light receiving elements, thus detecting the obstruction from an output of the detection circuit, and a rearward obstruction can be detected securely particularly when the car moves backward, a new light source for obstruction detecting is not particularly required, and thus no area must be prepared for installation.
    Type: Grant
    Filed: March 29, 1988
    Date of Patent: January 2, 1990
    Assignee: Stanley Electric Co., Ltd.
    Inventors: Kiyomitsu Ishikawa, Tohru Tanabe, Shigeru Kimura, Kazuhiko Yamada
  • Patent number: 4760162
    Abstract: An inorganic acid salt of N-[1(S)-ethyoxycarbonyl-3-phenylpropyl]-L-alanylchloride having the formula (I): ##STR1## A process for preparing an inorganic acid salt of N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanylchloride having the formula (I) ##STR2## which comprises reacting an inorganic acid salt of N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine with phosphorous pentachloride in an inactive organic solvent. According to the present invention, ACEI can be economically and easily prepared.
    Type: Grant
    Filed: August 25, 1986
    Date of Patent: July 26, 1988
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kazuhiko Yamada, Yoshifumi Yanagida, Satomi Takahashi, Takehisa Ohashi, Kiyoshi Watanabe
  • Patent number: 4733105
    Abstract: A CMOS output circuit including CMOS inverters, is formed on a semiconductor substrate and N MOS switching transistors are provided. The output circuit is responsive to an external control signal for switching a plurality of reference voltages and delivering them as multiple-level drive signals. The CMOS output circuit furthermore includes PMOS switching circuits connected in parallel with each of a plurality of CMOS transfer gates, CMOS inverters, and N MOS switching transistors for preventing a latch-up phenomenon of the CMOS inverters from being produced. The PMOS switching circuits are on-off controlled by a control signal obtained by converting an amplitude level of an external control signal.
    Type: Grant
    Filed: August 27, 1986
    Date of Patent: March 22, 1988
    Assignee: Oki Electric Industry Co., Ltd.
    Inventors: Yasuhiro Shin, Kazuhiko Yamada
  • Patent number: 4682271
    Abstract: A printed circuit board having a circuit pattern formed on at least one of the first and second faces of a substrate and having characters and symbols representing components to be mounted on said substrate printed on the first face and the second face of the substrate, wherein the characters printed on the first face have been printed in the reversed images in about the corresponding positions of the back face. Since the characters printed on the first face of the printed circuit board are also printed in the reversed images in the immediately corresponding positions of the second face of the board, these characters can be used as indexes to find a particular position on the printed circuit board, and the first or second face can be instantly distinguished from the second or first face.
    Type: Grant
    Filed: March 27, 1986
    Date of Patent: July 21, 1987
    Assignee: Kabushiki Kaisha Toshiba
    Inventor: Kazuhiko Yamada
  • Patent number: 4591554
    Abstract: A small number of microorganisms can be rapidly detected or determined by means of a fluorescence analysis method using specific umbelliferone derivatives such as 4-methylumbelliferyl phosphate and 4-methyl umbelliferyl galactoside, and this detecting method is applicable for a microbial inspection on sanitary quality of various kind of food, beverage, water and toilet article, or for a clinical inspection on a microbial infection.
    Type: Grant
    Filed: September 16, 1983
    Date of Patent: May 27, 1986
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ichiro Koumura, Hideo Kanou, Masahiko Okunishi, Kazuhiko Yamada
  • Patent number: 4426447
    Abstract: Dextransucrase synthesis of dextran from sucrose is inhibited by a novel homocitric acid oligoriboside derivative and its nontoxic salts. The new derivative is obtained by fermentation of certain Streptomyces sp. such as Streptomyces sp. MF 980-CF1 (FERM-P5430; ATCC 31820) and is useful in the prevention of dental caries.
    Type: Grant
    Filed: May 7, 1982
    Date of Patent: January 17, 1984
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Yoshiro Okami, Kazuhiko Yamada, Masachika Takashio
  • Patent number: 4376761
    Abstract: Dextransucrase synthesis of dextran from sucrose is inhibited by a novel homocitric acid oligoriboside derivative and its nontoxic salts. The new derivative is obtained by fermentation of certain Streptomyces sp. such as Streptomyces sp. MF 980-CF1 (FERM-P5430; ATCC 31820) and is useful in the prevention of dental caries.
    Type: Grant
    Filed: July 9, 1981
    Date of Patent: March 15, 1983
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Yoshiro Okami, Kazuhiko Yamada, Masachika Takashio
  • Patent number: 4106989
    Abstract: The present invention relates to a newly found thermostable cellulase of Sporotrichum cellulophilum and a method for producing the same.
    Type: Grant
    Filed: April 26, 1977
    Date of Patent: August 15, 1978
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ichiro Komura, Takeyoshi Awao, Kazuhiko Yamada
  • Patent number: 4016037
    Abstract: L-amino acids are produced by fermenting a hydantoin compound with Flavobacterium aminogenes or its enzymes.
    Type: Grant
    Filed: October 15, 1975
    Date of Patent: April 5, 1977
    Assignee: Ajinomoto Co., Inc.
    Inventors: Koji Mitsugi, Konosuke Sano, Kenzo Yokozeki, Kazuhiko Yamada, Ichiro Noda, Teruhiko Kagawa, Chikahiko Eguchi, Naohiko Yasuda, Fumihide Tamura, Kazushi Togo
  • Patent number: 4006057
    Abstract: A method for producing L-cysteine and/or L-cystine which comprises:A. holding 2-amino-thiazoline-4-carboxylic acid in an aqueous solution at a pH of 5 to 11 in the presence of an effective amount of enzyme produced by a microorganism; said enzyme being capable of converting the 2-amino-thiazoline-4-carboxylic acid to L-cysteine and/or L-cystine, and said microorganism being capable of growing in a medium containing 2-amino-thiazoline-4-carboxylic acid as a nitrogen source; andB. recovering the L-cysteine and/or L-cystine formed from said aqueous solution.
    Type: Grant
    Filed: November 4, 1975
    Date of Patent: February 1, 1977
    Assignee: Ajinomoto Co., Inc.
    Inventors: Konosuke Sano, Keizo Matsuda, Koji Mitsugi, Kazuhiko Yamada, Fumihide Tamura, Naohiko Yasuda, Ichiro Noda