Patents by Inventor Kazuhiko Yamane

Kazuhiko Yamane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9351949
    Abstract: Provided is a prophylactic/therapeutic agent for influenza viral infection that is effective not only before and at an early stage of infection with influenza virus but also at an intermediate or late stage of the infection and is highly safe for human bodies. A prophylactic/therapeutic drug for influenza viral infection comprising, as active ingredients, 5-aminolevulinic acid (5-ALA), a derivative thereof or a salt of the 5-ALA or the derivative, and an iron compound is prepared. This prophylactic/therapeutic agent can be used for ameliorating (preventing) depression in food consumption, water consumption and body weight, for ameliorating (decreasing) increase in ketone body levels in blood that may otherwise cause ketosis, for ameliorating (preventing) depression in ATP levels in blood, or for ameliorating (increasing) a survival rate and depression in a body surface temperature.
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: May 31, 2016
    Assignees: SBI Pharmaceuticals Co., Ltd., Tokushima University
    Inventors: Tohru Tanaka, Motowo Nakajima, Kiwamu Takahashi, Takuya Ishii, Hiroshi Kido, Junji Chida, Kazuhiko Yamane
  • Publication number: 20150344404
    Abstract: The present invention to provide a novel pyruvate dehydrogenase kinase inhibitors. A pyruvate dehydrogenase kinase inhibitor comprising a compound represented by the general formula (I) as an active ingredient (wherein, ring A represents a 6-membered aromatic hydrocarbon ring optionally substituted with 2-4 substituents, R1 and R4, which are the same or different, represent a hydrogen atom, a hydroxyl group, an optionally substituted C1-6 alkyl group, R2 and R3, which are the same or different, represent a hydrogen atom, a carboxyl group, an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group, or a group represented by —C (?R9)—R10), a pharmaceutical composition for treatment or prophylaxis of diseases or disorders that pyruvate dehydrogenase kinase relates to its development or aggravation, and a cosmetic composition, and the like.
    Type: Application
    Filed: December 26, 2013
    Publication date: December 3, 2015
    Inventors: Satoshi OMURA, Hirofumi NAKANO, Kenzaburo YAMAJI, Tsuyoshi YAMAMOTO, Hiroshi KIDO, Kazuhiko YAMANE, Toshiaki SUNAZUKA, Tomoyasu HIROSE
  • Publication number: 20150335610
    Abstract: The purpose of the present invention is to provide a therapeutic agent or preventive agent for exacerbation of influenza, specifically to provide a novel pyruvate dehydrogenase kinase 4 (PDK4) inhibitor. The present invention relates to a PDK4 inhibitor, medical composition or cosmetic composition containing as the active ingredient a compound represented by any one of the following general formulas (I) through (III) and a pharmaceutically acceptable ester derivative thereof, or a pharmaceutically acceptable salt of the same.
    Type: Application
    Filed: October 17, 2013
    Publication date: November 26, 2015
    Applicants: THE UNIVERSITY OF TOKUSHIMA, THE KITASATO INSTITUTE
    Inventors: Satoshi OMURA, Hirofumi NAKANO, Kenzaburo YAMAJI, Tsuyoshi YAMAMOTO, Hiroshi KIDO, Junji CHIDA, Kazuhiko YAMANE
  • Publication number: 20150164838
    Abstract: Provided is a prophylactic/therapeutic agent for influenza viral infection that is effective not only before and at an early stage of infection with influenza virus but also at an intermediate or late stage of the infection and is highly safe for human bodies. A prophylactic/therapeutic drug for influenza viral infection comprising, as active ingredients, 5-aminolevulinic acid (5-ALA), a derivative thereof or a salt of the 5-ALA or the derivative, and an iron compound is prepared. This prophylactic/therapeutic agent can be used for ameliorating (preventing) depression in food consumption, water consumption and body weight, for ameliorating (decreasing) increase in ketone body levels in blood that may otherwise cause ketosis, for ameliorating (preventing) depression in ATP levels in blood, or for ameliorating (increasing) a survival rate and depression in a body surface temperature.
    Type: Application
    Filed: June 3, 2013
    Publication date: June 18, 2015
    Applicants: SBI PHARMACEUTICALS CO., LTD., The University of Tokushima
    Inventors: Tohru Tanaka, Motowo Nakajima, Kiwamu Takahashi, Takuya Ishii, Hiroshi Kido, Junji Chida, Kazuhiko Yamane