Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.

Abstract: The invention provides micelles, pharmaceutical formulations comprising micells, solutions comprising micells, methods for preparing micells, methods for delivering micells to patients, and methods for treating sepsis, endotoxemia, septic shock and systemic inflamatory response syndrome in patients by adiministering micelles. The micelles comprises compounds of Forumala (A): wherein the substituents are as defined herein.

Abstract: The present invention provides an evaluation method and preparation process of injection containing a lipid A analog. Specifically, it provides, in an injection preparation containing a lipid A analog or a pharmacologically acceptable salt thereof, forecasting and evaluating methods of the pharmacokinetics of the lipid A analog, and quality evaluating method and preparation process of the injection, which each comprises measuring membrane fluidity and/or circular dichroism.

Abstract: A vessel is separated into at least two compartments by an easy-open peelable seal. At least one of the separated compartments is constituted of a laminate material. A gas barrier layer is provided to part of the laminate material so that the gas barrier layer may cover the entire surface of that compartment. An example of the vessel includes a vessel in which a laminate material comprised of at least an easy-open peelable material layer and a gas barrier layer is formed into a pouch shape, such that the easy-open peelable material layer is located on the inside of the vessel.

Abstract: A small drill includes one chip-discharging flute which is helically formed in the exterior surface of a cutting portion of the small drill. The small drill also includes a flute-shaped portion which is formed in the front region of the chip-discharging flute in the rotating direction, which is connected to the chip-discharging flute, and which is open at the exterior surface of the cutting portion. The core diameter ratio d/D, in percent, of the small drill is set to 60% or more, and a margin angle &thgr; thereof is set to 120° or more.

Abstract: A steering wheel includes a boss, a spoke, and an air bag apparatus with a bag and a synthetic resin cover. When the vehicle is subjected to a collision, the bag is inflated and rupture opens a front wall of the cover. The front wall has two side rupture lines, a dividing rupture line between the side rupture lines, a center rupture line from the dividing rupture line, and two upper hinges between the side rupture lines and the center rupture line. When the cover ruptures open, the rupture lines rupture, causing each lid to bend and swing about the upper hinges. The dividing rupture line is disposed at a position so that the upper lids do not interfere with the rim.

Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.

Abstract: There is provided a varistor having high surge resisting capability in spite of its small size and a method of manufacturing the same. The varistor is mainly composed of zinc oxide and contains a composite oxide expressed by the chemical formula Zn2SnO4. It is manufactured using a method wherein zinc oxide and tin oxide are mixed; the mixture is subjected to a thermal process thereafter to obtain a composite oxide expressed by the chemical formula Zn2SnO4; and the composite oxide is combined with the zinc oxide which is the main component and a thermal process is performed to obtain a raw material for the varistor.

Abstract: A core bar includes upper and lower half shells, each having a boss portion including a boss-edge coupling part for coupling the shells along the edges, a shaft fixing part placed substantially in the center of the boss portion and mounted to a steering shaft, and a weak part placed between the boss-edge coupling part and the shaft fixing part and wherein the shells face each other without being coupled; and a rim portion including a rim-edge coupling part for coupling the shells along the edges and a rim hollow part defined between the shells. A spoke portion is interposed between the boss and the rim portions, and includes a spoke-edge coupling part for coupling the shells along the edges and a spoke hollow part defined between the shells.

Abstract: An air bag is unfolded on a planar surface and is inflated with air. The air bag is loosely sandwiched between the upper and lower blades that are arranged in a radial configuration. Movable blocks progress toward the center to fold the upper and lower panels of the air bag against the central part of the air bag. The resulting central folded part of the air bag has a wave-like configuration, and the upper and lower panels are separated from each other. The ear-like portions of the air bag are wound around the central folded part of the air bag that is folded in a wave-like configuration. Then, the central part of the air bag is pressed downward to complete the folding process. Gas can be supplied smoothly from the inlet port to the periphery when the air bag is reinflated. The method for folding the air bag is simple, and the air bag can be inflated quickly.

Abstract: A pouch-shaped air bag (12) is spread out in a circle. Then, the portion of the air bag (12) located outside the inflator (16) is folded into a wave-like pattern from four directions so that four side portions (61) are formed along the inflator (16). Next, each one of the four excess portions (62), which are continuously formed between each two adjacent side portions (61) and protrude outward, is placed along the outer face of each side portion (61). Thus, the air bag (12) can be easily folded compactly that can be smoothly unfolded.

Abstract: A core bar for a steering wheel includes an upper shell and a lower shell coupled to the upper shell. Each half shell includes a boss core-bar portion coupled to a steering shaft, a rim core-bar portion, and a spoke core-bar portion interposed between the two. An insertion is received in a hollow defined by the upper and lower shells.

Abstract: An air bag body (1) is expanded by charging an air therein after being expanded in a flat surface shape. Next, by gently gripping the air bag body (1) by upper and lower blades (26, 25) radially arranged in a radial direction of the air bag body (1), a height in a radial direction of the air bag body (1) is linearly restricted along the upper and lower blades (26, 25). Next, a plurality of movable blocks (24) are forward moved toward a center of the air bag body (1), and upper and lower panels (12, 11) of the air bag body (1) are accumulated. At this time, the upper and lower panels (12, 11) of the air bag body (1) are folded in a state of being apart from each other so as to form a wave shape. Next, the air bag body (1) is rotated, a portion left in a tab shape is wound around a periphery, and a center protruding portion of the air bag body (1) is pressed from an upper side, whereby a front surface deploying portion (35) is formed.

Abstract: An air bag body (1) is expanded by charging air therein after being expanded in a flat surface shape. Next, by gently gripping the air bag body (1) by upper and lower blades (26, 25) radially arranged in a radial direction of the air bag body (1), height in a radial direction of the air bag body (1) is linearly restricted along the upper and lower blades (26, 25). Next, a plurality of movable blocks (24) are forward moved toward a center of the air bag body (1), and upper and lower panels (12, 11) of the air bag body (1) are accumulated. At this time, the upper and lower panels (12, 11) of the air bag body (1) are folded in a state of being apart from each other so as to form a wave shape. Next, the air bag body (1) is rotated, a portion left in a tab shape is wound around a periphery, and a center protruding portion of the air bag body (1) is pressed from an upper side, whereby a front surface deploying portion (35) is formed.

Abstract: A pouch-shaped air bag (12) is spread out in a circle. Then, the portion of the air bag (12) located outside the inflator (16) is folded into a wave-like pattern from four directions so that four side portions (61) are formed along the inflator (16). Next, each one of the four excess portions (62), which are continuously formed between each two adjacent side portions (61) and protrude outward, is placed along the outer face of each side portion (61). Thus, the air bag (12) can be easily folded compactly that can be smoothly unfolded.

Abstract: A pouch-shaped air bag (12) is spread out in a circle. Then, the portion of the air bag (12) located outside the inflator (16) is folded into a wave-like pattern from four directions so that four side portions (61) are formed along the inflator (16). Next, each one of the four excess portions (62), which are continuously formed between each two adjacent side portions (61) and protrude outward, is placed along the outer face of each side portion (61). Thus, the air bag (12) can be easily folded compactly that can be smoothly unfolded.

Abstract: An air bag device mounted on a steering wheel comprises a holding unit connected to a boss portion of the steering wheel. An inflater is held by the holding unit. The inflater includes a gas ejection portion. First and second fabrics have peripheral portions sewed together to constitute a bag structure. A gas inlet opening is formed in the first fabric. The gas inlet opening has the gas ejection portion of the inflater passed therethrough, so that the gas inlet opening is exposed to the interior of the bag structure. A third fabric is smaller in size than the first and second fabrics. The third fabric is installed in the bag structure in a manner to cover over the gas ejection portion of the inflater. A plurality of sewed points are provided by which the first and third fabrics are sewed together. A plurality of gas flow passages are provided between the first and third fabrics. Each gas flow passage is defined between neighboring two of the sewed points.

Abstract: An airbag includes first and second base cloths and a middle base cloth arranged therebetween for defining first and second compartments in the airbag. Gas communicating ports are arranged in the vicinity of the outer periphery of the middle base cloth to ensure gas communication between the two compartments. Four ring-shaped fixing portions are arranged around a gas introduction port to connect the second and middle base cloths, one of which has an exhaust port formed inside.

Abstract: A steering wheel includes a boss, a spoke, and an air bag apparatus with a bag and a synthetic resin cover. When the vehicle is subjected to a collision, the bag is inflated and rupture opens a front wall of the cover. The front wall has two side rupture lines, a dividing rupture line between the side rupture lines, a center rupture line from the dividing rupture line, and two upper hinges between the side rupture lines and the center rupture line. When the cover ruptures open, the rupture lines rupture, causing each lid to bend and swing about the upper hinges. The dividing rupture line is disposed at a position so that the upper lids do not interfere with the rim.

Abstract: There is provided a varistor having high surge resisting capability in spite of its small size and a method of manufacturing the same. The varistor is mainly composed of zinc oxide and contains a composite oxide expressed by the chemical formula Zn2SnO4. It is manufactured using a method wherein zinc oxide and tin oxide are mixed; the mixture is subjected to a thermal process thereafter to obtain a composite oxide expressed by the chemical formula Zn2SnO4; and the composite oxide is combined with the zinc oxide which is the main component and a thermal process is performed to obtain a raw material for the varistor.