Patents by Inventor Kazuhiro Machida

Kazuhiro Machida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190101621
    Abstract: A vehicle-mounted radar device has: a radar transmitting circuit transmitting a radar transmission waves to be reflected at a target; a radar receiving circuit receiving the reflected waves; a radar's axial deviation detecting circuit deciding whether the radar axis of the radar device has a deviation, according to the difference between a first value (distance between the vehicle and the known still object based on a shape of the known still object) and a second value (distance between them at a time when a radar reflected wave having attenuated power of the known still object among the radar reflected waves is received); and an axial deviation notifying circuit making a notification of the axial deviation.
    Type: Application
    Filed: September 25, 2018
    Publication date: April 4, 2019
    Inventors: KAZUHIRO MACHIDA, HIDEKUNI YOMO, JUNJI SATO, AKIHIKO MATSUOKA, TOMOHIRO MURATA, TAKAYUKI ABE, KENTA IWASA
  • Patent number: 8735135
    Abstract: Disclosed is a means for improving the poor conversion efficiency in a conventional bioconversion system using a transformant which is given by introducing a gene originated from xerogenic organisms. A transformant is prepared by using a host which is defective in a gene encoding a multidrug efflux protein and introducing a gene originated from xerogenic organisms. Use of the transformant results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound. In case, an Escherichia coli is used as the host, the gene encoding a multidrug efflux protein to be defective may be tolC, acrA, acrB and the like.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: May 27, 2014
    Assignee: Microbiopharm Japan Co., Ltd
    Inventors: Tadashi Fujii, Atsushi Ochiai, Masashi Ito, Hiroki Kabumoto, Yoshikazu Fujii, Kazuhiro Machida
  • Patent number: 8512995
    Abstract: The nucleotide sequence of a DNA involved in the biosynthesis of herboxidiene was determined. Utilizing this DNA, herboxidiene and analogues thereof can be efficiently produced.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: August 20, 2013
    Assignees: Eisai R&D Management Co., Ltd., Micro Biopharm Japan Co., Ltd.
    Inventors: Kazuhiro Machida, Kaoru Okayama, Masashi Itoh, Asako Toyoda
  • Patent number: 8460915
    Abstract: Disclosed is a means for improving the poor conversion efficiency in a bioconversion system using an Escherichia coli cell having a bacterium-originated cytochrome P-450 gene integrated therein. A recombinant Escherichia coli cell is produced by introducing aciB and aciC which encode a gene for the electron transport system originated from the Acinetobacter sp. OC4 strain into an Escherichia coli cell, and adding a polynucleotide encoding an N-terminal sequence composed of 48 amino acid residues of AciA and the like to the 5?-terminus of a bacterium-originated cytochrome P-450 gene, wherein AciA is an alkane-oxidative cytochrome P-450 originated from the Acinetobacter sp. OC4 strain. Use of the recombinant Escherichia coli cell results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: June 11, 2013
    Assignee: Microbiopharm Japan Co., Ltd.
    Inventors: Tadashi Fujii, Yoshikazu Fujii, Atsushi Ochiai, Masashi Ito, Kazuhiro Machida
  • Publication number: 20120040441
    Abstract: Disclosed is a means for improving the poor conversion efficiency in a conventional bioconversion system using a transformant which is given by introducing a gene originated from xerogenic organisms. A transformant is prepared by using a host which is defective in a gene encoding a multidrug efflux protein and introducing a gene originated from xerogenic organisms. Use of the transformant results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound. In case, an Escherichia coli is used as the host, the gene encoding a multidrug efflux protein to be defective may be tolC, acrA, acrB and the like.
    Type: Application
    Filed: February 28, 2008
    Publication date: February 16, 2012
    Applicant: MERCIAN CORPORATION
    Inventors: Tadashi Fujii, Atsushi Ochiai, Masashi Ito, Hiroki Kabumoto, Yoshikazu Fujii, Kazuhiro Machida
  • Publication number: 20110295023
    Abstract: The nucleotide sequence of a DNA involved in the biosynthesis of herboxidiene was determined. Utilizing this DNA, herboxidiene and analogues thereof can be efficiently produced.
    Type: Application
    Filed: May 27, 2009
    Publication date: December 1, 2011
    Applicants: MERCIAN CORPORATION
    Inventors: Kazuhiro Machida, Kaoru Okayama, Masashi Itoh, Asako Toyoda
  • Patent number: 8008049
    Abstract: The present invention provides polypeptides that participate in the biosynthesis of the pladienolide macrolide compounds, DNA that encodes these polypeptides and variants of this DNA, transformants that maintain all or a portion of this DNA or variant thereof, and a method of producing the pladienolide macrolide compounds using these transformants. More particularly, it provides an isolated pure DNA that contains at least one region encoding a polypeptide that participates in pladienolide biosynthesis; polypeptide encoded by this DNA; a self-replicating or integrated-replicating recombinant plasmid carrying this DNA; a transformant maintaining this DNA; and a method of producing a pladienolide, characterized by culturing this transformant on culture medium and collecting pladienolide from this culture medium.
    Type: Grant
    Filed: July 19, 2005
    Date of Patent: August 30, 2011
    Assignee: EISAI R&D Management Co., Ltd.
    Inventors: Kazuhiro Machida, Akira Arisawa, Susumu Takeda, Masashi Yoshida, Toshio Tsuchida
  • Patent number: 7932083
    Abstract: The present invention provides a DNA participating in biological transformation of a macrolide compound 11107B. The present invention provides, particularly, a DNA participating in biological transformation of a macrolide compound 11107B represented by the formula (I) into a 16-position hydroxy macrolide compound 11107D represented by the formula (II), the DNA encoding a protein having 16-position hydroxylating enzymatic activity or ferredoxin, to a method of isolating the DNA, to a protein encoded by the DNA, a plasmid carrying the DNA, a transformant obtained by transforming using the plasmid and a method of producing a 16-position hydroxy compound by using the transformant.
    Type: Grant
    Filed: November 25, 2004
    Date of Patent: April 26, 2011
    Assignees: Mercian Corporation, Eisai R&D Management Co., Ltd.
    Inventors: Kazuhiro Machida, Takashi Nakashima, Yasuhide Aritoku, Toshio Tsuchida
  • Publication number: 20100285565
    Abstract: Disclosed is a means for improving the poor conversion efficiency in a bioconversion system using an Escherichia coli cell having a bacterium-originated cytochrome P-450 gene integrated therein. A recombinant Escherichia coli cell is produced by introducing aciB and aciC which encode a gene for the electron transport system originated from the Acinetobacter sp. OC4 strain into an Escherichia coli cell, and adding a polynucleotide encoding an N-terminal sequence composed of 48 amino acid residues of AciA and the like to the 5?-terminus of a bacterium-originated cytochrome P-450 gene, wherein AciA is an alkane-oxidative cytochrome P-450 originated from the Acinetobacter sp. OC4 strain. Use of the recombinant Escherichia coli cell results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound.
    Type: Application
    Filed: February 28, 2008
    Publication date: November 11, 2010
    Inventors: Tadashi Fujii, Yoshikazu Fujii, Atsushi Ochiai, Masashi Ito, Kazuhiro Machida
  • Publication number: 20090269820
    Abstract: The present invention provides polypeptides that participate in the biosynthesis of the pladienolide macrolide compounds, DNA that encodes these polypeptides and variants of this DNA, transformants that maintain all or a portion of this DNA or variant thereof, and a method of producing the pladienolide macrolide compounds using these transformants. More particularly, it provides an isolated pure DNA that contains at least one region encoding a polypeptide that participates in pladienolide biosynthesis; polypeptide encoded by this DNA; a self-replicating or integrated-replicating recombinant plasmid carrying this DNA; a transformant maintaining this DNA; and a method of producing a pladienolide, characterized by culturing this transformant on culture medium and collecting pladienolide from this culture medium.
    Type: Application
    Filed: July 19, 2005
    Publication date: October 29, 2009
    Inventors: Kazuhiro Machida, Akira Arisawa, Susumu Takeda, Masashi Yoshida, Toshio Tsuchida
  • Publication number: 20090215134
    Abstract: A genetically modified microorganism capable of directly producing a 16-hydroxylated macrolide compound; and a process for producing a 16-hydroxylated macrolide compound using the microorganism. Specifically, a genetically modified microorganisms having DNA encoding a polypeptide involved in the biosynthesis of a macrolide compound pladienolide and DNA encoding a polypeptide having a pladienolide 16-hydroxylase activity; and a process for producing a 16-hydroxylated macrolide compound comprising the steps of culturing the genetically modified microorganism in a culture medium and collecting a 16-hydroxylated macrolide compound from the culture medium.
    Type: Application
    Filed: May 24, 2006
    Publication date: August 27, 2009
    Inventors: Kazuhiro Machida, Yasuhide Aritoku
  • Publication number: 20080070286
    Abstract: The present invention provides a DNA participating in biological transformation of a macrolide compound 11107B. The present invention provides, particularly, a DNA participating in biological transformation of a macrolide compound 11107B represented by the formula (I) into a 16-position hydroxy macrolide compound 11107D represented by the formula (II), the DNA encoding a protein having 16-position hydroxylating enzymatic activity or ferredoxin, to a method of isolating the DNA, to a protein encoded by the DNA, a plasmid carrying the DNA, a transformant obtained by transforming using the plasmid and a method of producing a 16-position hydroxy compound by using the transformant.
    Type: Application
    Filed: November 25, 2004
    Publication date: March 20, 2008
    Inventors: Kazuhiro Machida, Yasuhide Aritoku, Toshio Tsuchida, Takashi Nakashima
  • Publication number: 20070157225
    Abstract: The receiving terminal apparatus of a broadcasting system includes a receiving unit configured to receive coupon information that includes service additional information and coupon indirect information used to issue a coupon, the service additional information including user profile information that designates a requirement to identify target viewers. A managing unit is provided that is configured to store and manage attribute information of a user of the receiving terminal apparatus. A determining unit is provided to determine whether the attribute information of the user stored by the managing unit meets the requirement designated by the user profile information, and to display the coupon information when it is determined that the attribute information of the user managed by the managing unit meets the requirement designated by the user profile information. A method is also disclosed using the apparatus in order to display the coupon information if the designated requirements are met.
    Type: Application
    Filed: October 18, 2006
    Publication date: July 5, 2007
    Applicant: Matsushita Electric Industrial Co., Ltd.
    Inventors: Takenosuke Harada, Kazuhiro Machida, Isao Kandaka, Akira Usui
  • Publication number: 20040133847
    Abstract: The present invention is intended to electronically sell digital contents to moving users anytime. Each user's receiving terminal includes a unit of monitoring conditions of communication with a digital content distribution apparatus run by a content provider and, according to the communication conditions, the receiving terminal sends its equipment identifier data to the digital content distribution apparatus to designate the receiving terminal. The digital content distribution apparatus includes a unit of download and stock management which manages content download and stock data descriptive of content volumes downloaded and stocked in the receiving terminals, associated with the equipment identifier, and a unit of determining a digital content to download which determines a digital content to download to the receiving terminals, based on the content download and stock data, and downloads the digital content to the receiving terminals.
    Type: Application
    Filed: October 8, 2003
    Publication date: July 8, 2004
    Applicant: Matsushita Electric Industrial Co., Ltd.
    Inventors: Daisuke Iino, Kenichi Fujita, Kazuhiro Machida, Asako Saito
  • Patent number: 6714649
    Abstract: In a pay broadcasting system, data of a broadcast program is scrambled with a scramble key updated in a short period. The scramble key is encrypted with a first key assigned to the subscriber terminal. The first key is encrypted with a first master key set in the subscriber terminal. The security of a broadcast program stored for subsequent use in the subscriber terminal is enhanced as follows. A central station generates a second key-encrypted scramble key by encrypting the scramble key with a second key different from the first key and changeable in an interval shorter than a update interval of the first key; generates an encrypted second key by encrypting the second key with a second master key which has been commonly issued to subscriber terminals of the system; and broadcast the second key-encrypted scramble key and the encrypted second key together with the scrambled data of the program, the first key-encrypted scramble key and the encrypted first key in a multiplexed manner.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: March 30, 2004
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Isao Masuda, Yoshimasa Goto, Takenosuke Harada, Kazuhiro Machida, Mitsuteru Kataoka
  • Patent number: 6546556
    Abstract: A tagged scene of a video stream transmitted from a first to second stations in television broadcasting system is collected while preventing the tags from being used for commercial cutting (i.e., indiscriminate tagged scene cutting). The first station generates for each scene a tag includes a category, a location for use in locating a beginning of the scene and a length. A second station obtains a desired category from the user. Detecting a tag in the video stream, if the category coincides with the desired category, the second station clips from the video stream a part of the length defined in the tag from a position located by using the location.
    Type: Grant
    Filed: December 28, 1998
    Date of Patent: April 8, 2003
    Assignees: Matsushita Electric Industrial Co., Ltd., Information Broadcasting Laboratories, Inc.
    Inventors: Mitsuteru Kataoka, Kazuhiro Machida, Takenosuke Harada
  • Publication number: 20020120927
    Abstract: In a broadcasting system including a center and an information broadcast receiving terminal apparatus, contents data of services of each of various data and service additional information in which information relating to these services is described are made in the center. The contents data of services and the service additional information are broadcasted from a service providing apparatus provided in the center. The information broadcast receiving terminal apparatus receives and accumulates the contents data of services and the service additional information therein. When a user of the information broadcast receiving terminal apparatus regenerates the contents data of services and the service additional information to view the program, the information broadcast receiving terminal apparatus provides an additional service on the basis of the service additional information.
    Type: Application
    Filed: August 13, 2001
    Publication date: August 29, 2002
    Applicant: Matsushita Electric Industrial Co., Ltd.
    Inventors: Takenosuke Harada, Kazuhiro Machida, Isao Kandaka, Akira Usui
  • Publication number: 20020059624
    Abstract: A server based broadcast system has a receiver capable of automatically storing broadcasted contents and allowing a user to enjoy playback of an intended service element involved in the stored contents. Information necessary to operate this server based broadcast system, such as service component information and renewal schedule, is transmitted as a meta-content equivalent to a content composing the substance of this server based broadcast service. Content information, including private information inherent to each content as well as common information applicable to a plurality of contents, is added to each content to be broadcasted and carried on a carousel for data broadcasting. A receiver makes a content group with reference to the common information.
    Type: Application
    Filed: August 1, 2001
    Publication date: May 16, 2002
    Inventors: Kazuhiro Machida, Yuko Arai, Hiroyuki Nishi
  • Patent number: 6262721
    Abstract: Viewer individual attribute information indicating an attribute of a particular viewer such as an age, male or female, a resident district, a taste, an occupation and a life style is stored in a receiving terminal apparatus of the particular viewer. When a broadcasting program is transmitted from a service supply apparatus to the receiving terminal apparatus, service addition information indicating an attribute of the broadcasting program or an attribute condition required of viewers is transmitted to the receiving terminal apparatus with contents of the broadcasting program. In the receiving terminal apparatus, the service addition information is collated with the viewer individual attribute information of the particular viewer, and it is judged whether or not the broadcasting program is suitable for the particular viewer. In cases where the broadcasting program is suitable for the particular viewer, the broadcasting program is received by the receiving terminal apparatus and is reproduced and displayed.
    Type: Grant
    Filed: July 3, 1997
    Date of Patent: July 17, 2001
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Ryota Tsukidate, Yoshiyasu Takeuchi, Kazuhiro Machida, Takenosuke Harada, Shigeki Kaneko, Kenichi Fujita, Yoshimasa Goto
  • Patent number: 6243469
    Abstract: The present invention provides an information transmission apparatus and method for an information transmission system where encrypted information comprised of a plurality of information units each hierarchically encrypted and multiplexed to each other is communicated between at least two parties, wherein the information is being encrypted for transmission. The information transmission system is constructed by a transmitting unit and a receiving unit.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: June 5, 2001
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Mitsuteru Kataoka, Takenosuke Harada, Kazuhiro Machida, Isao Masuda