Patents by Inventor Kazuhiro Miwa

Kazuhiro Miwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10539274
    Abstract: A light emitting device includes a plurality of LED strings connected in parallel, wherein: each of the LED strings includes a plurality of LED chips connected in series to each other; in the LED string, ultraviolet light LED chips and blue LED chips or violet LED chips and blue LED chips are connected in series to each other; and the number of the ultraviolet light LED chips or the number of the violet LED chips is the same as the number of the blue LED chips in each of the plurality of LED strings.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: January 21, 2020
    Assignee: TOYODA GOSEI CO., LTD.
    Inventors: Tomohiro Miwa, Kazuhiro Sakai, Shota Shimonishi, Shigeo Takeda
  • Patent number: 10464945
    Abstract: The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl) -5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine -2,4(1H,3H)-dione or salt thereof, 1,1?-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: November 5, 2019
    Assignee: Takeda Pharmaceutical Company Limited
    Inventor: Kazuhiro Miwa
  • Patent number: 10428895
    Abstract: A valve mechanism includes a housing, a plate-shaped valve body, a valve positioning member, and a drive valve moving mechanism. The valve positioning member causes the valve body to face the valve seat via a predetermined gap with respect to the valve seat. The drive valve moving mechanism causes the gap between an inner circumference of the valve body and the valve seat to be variable by moving the drive valve in a direction of approaching the valve seat and elastically deforming the valve body in a direction that the inner circumference of the valve body approaches the valve seat.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: October 1, 2019
    Assignee: Showa Corporation
    Inventors: Kazuhiro Miwa, Yosuke Murakami
  • Publication number: 20190219126
    Abstract: There is provided a compact damping force variable shock absorber capable of implementing different adjustments for a compression-side stroke and an extension-side stroke as initial settings. A damping force variable device in one embodiment includes: a main valve that opens and closes to control flow of oil caused by sliding of a piston in a cylinder, thereby generating damping force; a pilot chamber into which a portion of the flow of the oil is introduced so that internal pressure is applied to the main valve in a valve-closing direction; a pilot valve that opens and closes to adjust the internal pressure of the pilot chamber; and a communication passage that communicates the pilot chamber with a rod-side oil chamber or a piston-side fluid chamber.
    Type: Application
    Filed: March 20, 2019
    Publication date: July 18, 2019
    Applicant: Showa Corporation
    Inventors: Kazuhiro MIWA, Naoya KUROIWA
  • Publication number: 20190198441
    Abstract: A semiconductor device includes: a semiconductor element; a support as a metallic member that includes a metallized layer having a first component as an iron group element and a second component as a periodic table group five or group six transition metal element other than chromium provided at an outermost surface of the support, and is arranged such that the outermost surface faces the semiconductor element; a joint material that is arranged between the outermost surface of the support and the semiconductor element, and is joined with the outermost surface to fix the semiconductor element to the support; and a molding resin that is arranged to cover a joint body having the support, the joint material and the semiconductor element.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 27, 2019
    Inventors: Tomohito IWASHIGE, Kazuhiko SUGIURA, Kazuhiro MIWA, Yuichi SAKUMA, Seigo KUROSAKA, Yukinori ODA
  • Publication number: 20190127016
    Abstract: A hydraulic shock absorber includes a control valve. The control valve includes a valve seat formed with a closing face, a valve body configured to come into contact with the closing face, and a valve shaft configured to transmit an operation force applied from a driving unit to the valve body. The control valve is defined with an upstream side flow channel extending from an inlet coupled to the upper end opening, via a space in which the valve body moves, to the closing face, and a downstream side flow channel extending from the closing face to an outlet. The control valve is disposed above the cylinder so that a central axis of the valve shaft is inclined relative to a central axis of the vehicle body side tube and the wheel side tube.
    Type: Application
    Filed: February 8, 2017
    Publication date: May 2, 2019
    Applicant: Showa Corporation
    Inventors: Yosuke MURAKAMI, Kazuhiro MIWA, Naoya KUROIWA
  • Publication number: 20190055261
    Abstract: The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or salt thereof, 1,1?-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
    Type: Application
    Filed: August 29, 2018
    Publication date: February 21, 2019
    Inventor: Kazuhiro MIWA
  • Patent number: 10150778
    Abstract: The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or salt thereof, 1,1?-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: December 11, 2018
    Assignee: Takeda Pharmaceutical Company Limited
    Inventor: Kazuhiro Miwa
  • Publication number: 20180319816
    Abstract: The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or salt thereof, 1,1?-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 8, 2018
    Inventors: Kazuhiro MIWA, Tsuyoshi SASAKI, Fumiya KOMURA
  • Patent number: 10060497
    Abstract: A damping-force generating device included in a shock absorber includes: a main valve that opens and closes for controlling a flow of oil (working fluid) caused by sliding of a piston in a cylinder and thereby generates a damping force; a first pressure chamber and a second pressure chamber separated by the main valve; a compression-side inlet check valve and an extension-side inlet check valve that allow only inflow of the oil into the first pressure chamber; and a compression-side outlet check valve and an extension-side outlet check valve that allow only outflow of the oil from the second pressure chamber. The first pressure chamber and the second pressure chamber are formed in a substantially double-ring structure.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: August 28, 2018
    Assignee: SHOWA CORPORATION
    Inventors: Yosuke Murakami, Kazuhiro Miwa
  • Patent number: 9878981
    Abstract: Provided is a production method of a synthetic intermediate for a heterocyclic compound having a renin inhibitory activity and useful as a prophylactic or therapeutic drug for diabetic nephropathy, hypertension and the like. A production method of a compound represented by the formula (III-1a), the formula (III-1b), the formula (III-1c) and/or the formula (III-1d); wherein each symbol is as described in DESCRIPTION, or a salt thereof, including reacting a compound represented by the formula (Ia) or (Ib): wherein each symbol is as described in DESCRIPTION, or a salt thereof with a compound represented by the formula (II): wherein each symbol is as described in DESCRIPTION, or a salt thereof, in the presence of an aluminum compound and a chiral amine compound.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: January 30, 2018
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Hironori Yamashita, Kazuhiro Miwa
  • Patent number: 9849934
    Abstract: A shock absorber includes a cylinder in which oil is sealed, a piston slidably fitted into the cylinder, a piston rod connected to the piston and extending to the outside of the cylinder, and a damping force generating apparatus controlling a flow of the oil generated by the sliding of the piston inside the cylinder. The damping force generating apparatus includes a valve body generating a damping force by being opened and closed on a flow path in which the oil flows, a valve seat closing the flow path when the valve body is seated, and an actuator generating thrust to the valve body in a valve closing direction. The valve seat has a first elastic body which is elastically deformable in the valve closing direction of the valve body.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: December 26, 2017
    Assignee: SHOWA CORPORATION
    Inventors: Kazuhiro Miwa, Naoya Kuroiwa
  • Publication number: 20170284496
    Abstract: A valve mechanism includes a housing, a plate-shaped valve body, a valve positioning member, and a drive valve moving mechanism. The valve positioning member causes the valve body to face the valve seat via a predetermined gap with respect to the valve seat. The drive valve moving mechanism causes the gap between an inner circumference of the valve body and the valve seat to be variable by moving the drive valve in a direction of approaching the valve seat and elastically deforming the valve body in a direction that the inner circumference of the valve body approaches the valve seat.
    Type: Application
    Filed: September 8, 2016
    Publication date: October 5, 2017
    Applicant: Showa Corporation
    Inventors: Kazuhiro MIWA, Yosuke MURAKAMI
  • Patent number: 9758528
    Abstract: The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethyl aminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or salt thereof, 1,1?-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: September 12, 2017
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Koichiro Fukuoka, Kazuhiro Miwa, Tsuyoshi Sasaki, Fumiya Komura
  • Publication number: 20170210753
    Abstract: The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or salt thereof, 1,1?-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
    Type: Application
    Filed: April 7, 2017
    Publication date: July 27, 2017
    Inventors: Koichiro FUKUOKA, Kazuhiro MIWA, Tsuyoshi SASAKI, Fumiya KOMURA
  • Patent number: 9695898
    Abstract: A damping force generating apparatus of a shock absorber includes a main flow path through which a working fluid flows, a main valve which generates a damping force by controlling the flow of the working fluid by opening and closing the main flow path, a pilot chamber into which the working fluid branched from the main flow path flows and which applies an internal pressure in a valve closing direction to the main valve by a pressure of the working fluid, and a pilot flow path to which the working fluid flows out from the pilot chamber. In addition, a jet stream which is generated in a flow path narrowed by the main valve in the main flow path joins the flow of the working fluid which flows out from the pilot chamber via the pilot flow path.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: July 4, 2017
    Assignee: SHOWA CORPORATION
    Inventors: Yosuke Murakami, Kazuhiro Miwa
  • Publication number: 20170121286
    Abstract: Provided is a production method of a synthetic intermediate for a heterocyclic compound having a renin inhibitory activity and useful as a prophylactic or therapeutic drug for diabetic nephropathy, hypertension and the like. A production method of a compound represented by the formula (III-1a), the formula (III-1b), the formula (III-1c) and/or the formula (III-1d); wherein each symbol is as described in DESCRIPTION, or a salt thereof, including reacting a compound represented by the formula (Ia) or (Ib): wherein each symbol is as described in DESCRIPTION, or a salt thereof with a compound represented by the formula (II): wherein each symbol is as described in DESCRIPTION, or a salt thereof, in the presence of an aluminum compound and a chiral amine compound.
    Type: Application
    Filed: April 9, 2015
    Publication date: May 4, 2017
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Hironori YAMASHITA, Kazuhiro MIWA
  • Patent number: 9550545
    Abstract: A shock absorber includes: a valve body; a valve seat; an actuator; and a fail-safe valve that is urged by a first elastic body. When fluid does not flow, the fail-safe valve is urged by the first elastic body to come into contact with the valve body and close a channel. When the fluid flows, the fail-safe valve is spaced from the valve body by a fluid pressure to open the channel. When the valve body moves most in a valve opening direction, the fail-safe valve is brought into contact with the valve body and the channel is closed, and a supporting portion supports a part of the fail-safe valve. When the fluid flows in this state, at least a part of the fail-safe valve, which is in contact with a non-supporting portion, is spaced from the valve body by the fluid pressure to open the channel.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: January 24, 2017
    Assignee: SHOWA CORPORATION
    Inventors: Yosuke Murakami, Kazuhiro Miwa
  • Publication number: 20160369862
    Abstract: There is provided a compact damping force variable shock absorber capable of implementing different adjustments for a compression-side stroke and an extension-side stroke as initial settings. A damping force variable device in one embodiment includes: a main valve that opens and closes to control flow of oil caused by sliding of a piston in a cylinder, thereby generating damping force; a pilot chamber into which a portion of the flow of the oil is introduced so that internal pressure is applied to the main valve in a valve-closing direction; a pilot valve that opens and closes to adjust the internal pressure of the pilot chamber; and a communication passage that communicates the pilot chamber with a rod-side oil chamber or a piston-side fluid chamber.
    Type: Application
    Filed: June 16, 2016
    Publication date: December 22, 2016
    Applicant: Showa Corporation
    Inventors: Kazuhiro MIWA, Naoya KUROIWA
  • Publication number: 20160288869
    Abstract: A shock absorber includes a cylinder in which oil is sealed, a piston slidably fitted into the cylinder, a piston rod connected to the piston and extending to the outside of the cylinder, and a damping force generating apparatus controlling a flow of the oil generated by the sliding of the piston inside the cylinder. The damping force generating apparatus includes a valve body generating a damping force by being opened and closed on a flow path in which the oil flows, a valve seat closing the flow path when the valve body is seated, and an actuator generating thrust to the valve body in a valve closing direction. The valve seat has a first elastic body which is elastically deformable in the valve closing direction of the valve body.
    Type: Application
    Filed: March 10, 2016
    Publication date: October 6, 2016
    Applicant: Showa Corporation
    Inventors: Kazuhiro MIWA, Naoya KUROIWA