Patents by Inventor Kazuhiro OHDACHI

Kazuhiro OHDACHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240109842
    Abstract: Provided is an acrylamide compound, which is useful for the promotion of platelet production from platelet progenitor cells such as megakaryocytes in vitro and represented by general formula [I]: wherein each symbol is as defined in the description.
    Type: Application
    Filed: December 8, 2020
    Publication date: April 4, 2024
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Hideki HAYASHI, Ryosuke TAGA, Yuki SAKAMOTO, Nozomi KUWANO, Kurumi MINENO, Kazuhiro OHDACHI, Yusuke FUJIMORI
  • Patent number: 11932657
    Abstract: Provided is a novel heterocyclic compound having an aryl hydrocarbon receptor antagonist activity and useful for the promotion of platelet production, the compound being represented by the general formula [I]: wherein ring A, ring B, R1, R2, R3, R4, n, and X are as defined above, or a salt thereof.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: March 19, 2024
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Kazuhiro Ohdachi, Yusuke Fujimori, Naoya Makita, Noritaka Koseki, Hideki Hayashi, Yuki Sakamoto, Kurumi Mineno, Ryosuke Taga
  • Publication number: 20230265073
    Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
    Type: Application
    Filed: April 27, 2023
    Publication date: August 24, 2023
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Keizo KAN, Masatoshi TAKUWA, Hirotaka TANAKA, Hideto FUJIWARA, Hokuto YAMABE, Satoshi MATSUDA, Kazuhiro OHDACHI, Taiki HANARI, Yasuhiro MENJO, Tatsuya URUSHIMA, Shigekazu FUJITA
  • Patent number: 11673878
    Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: June 13, 2023
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Keizo Kan, Masatoshi Takuwa, Hirotaka Tanaka, Hideto Fujiwara, Hokuto Yamabe, Satoshi Matsuda, Kazuhiro Ohdachi, Taiki Hanari, Yasuhiro Menjo, Tatsuya Urushima, Shigekazu Fujita
  • Publication number: 20210340157
    Abstract: Provided is a novel heterocyclic compound having an aryl hydrocarbon receptor antagonist activity and useful for the promotion of platelet production, the compound being represented by the general formula [I]: wherein ring A, ring B, R1, R2, R3, R4, n, and X are as defined above, or a salt thereof.
    Type: Application
    Filed: September 6, 2019
    Publication date: November 4, 2021
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Kazuhiro OHDACHI, Yusuke FUJIMORI, Naoya MAKITA, Noritaka KOSEKI, Hideki HAYASHI, Yuki SAKAMOTO, Kurumi MINENO, Ryosuke TAGA
  • Publication number: 20210078976
    Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
    Type: Application
    Filed: November 24, 2020
    Publication date: March 18, 2021
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Keizo KAN, Masatoshi TAKUWA, Hirotaka TANAKA, Hideto FUJIWARA, Hokuto YAMABE, Satoshi MATSUDA, Kazuhiro OHDACHI, Taiki HANARI, Yasuhiro MENJO, Tatsuya URUSHIMA, Shigekazu FUJITA
  • Patent number: 10889570
    Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: January 12, 2021
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Keizo Kan, Masatoshi Takuwa, Hirotaka Tanaka, Hideto Fujiwara, Hokuto Yamabe, Satoshi Matsuda, Kazuhiro Ohdachi, Taiki Hanari, Yasuhiro Menjo, Tatsuya Urushima, Shigekazu Fujita
  • Publication number: 20190389838
    Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
    Type: Application
    Filed: June 29, 2018
    Publication date: December 26, 2019
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Keizo KAN, Masatoshi TAKUWA, Hirotaka TANAKA, Hideto FUJIWARA, Hokuto YAMABE, Satoshi MATSUDA, Kazuhiro OHDACHI, Taiki HANARI, Yasuhiro MENJO, Tatsuya URUSHIMA, Shigekazu FUJITA