Patent number: 7776578
Abstract: Provided in the present invention is an alkaline protease wherein an amino acid residue at (a) position 65, (b) position 101, (c) position 163, (d) position 170, (e) position 171, (f) position 273, (g) position 320, (h) position 359 or (i) position 387 of SEQ. ID NO:1 or at a position corresponding thereto has been selected from the following amino acid residues: position (a): proline, position (b): asparagine, position (c): histidine, aspartic acid, phenylalanine, lysine, asparagine, serine, isoleucine, leucine, glutamine, threonine and valine, position (d): valine and leucine, position (e): alanine, glutamic acid, glycine and threonine, position (f): isoleucine, glycine and threonine, position (g): phenylalanine, valine, threonine, leucine, isoleucine and glycine, position (h): serine, leucine, valine, isoleucine and glutamine, position (i): alanine, lysine, glutamine, glutamic acid, arginine and histidine.
Type:
Grant
Filed:
March 14, 2008
Date of Patent:
August 17, 2010
Assignee:
Kao Corporation
Inventors:
Mitsuyoshi Okuda, Tsuyoshi Sato, Kazuhiro Saito, Nobuyuki Sumitomo, Yoshifumi Izawa, Katsuhisa Saeki, Tohru Kobayashi, Masafumi Nomura