Abstract: A process for the production of a fluorinated organic compound, characterized by fluorinating an organic compound having a hydrogen atoms using IF5; and a novel fluorination process for fluorinating an organic compound having a hydrogen atoms by using a fluorinating agent containing IF5 and at least one member selected from the group consisting of acids, bases, salts and additives.

Abstract: A process for the production of a fluorinated organic compound, characterized by fluorinating an organic compound having a hydrogen atoms using IF5; and a novel fluorination process for fluorinating an organic compound having a hydrogen atoms by using a fluorinating agent containing IF5 and at least one member selected from the group consisting of acids, bases, salts and additives.

Abstract: A process for the production of a fluorinated organic compound, characterized by fluorinating an organic compound having a hydrogen atoms using IF5; and a novel fluorination process for fluorinating an organic compound having a hydrogen atoms by using a fluorinating agent containing IF5 and at least one member selected from the group consisting of acids, bases, salts and additives.

Abstract: A process for the production of a fluorinated organic compound, characterized by fluorinating an organic compound having a hydrogen atoms using IF5; and a novel fluorination process for fluorinating an organic compound having a hydrogen atoms by using a fluorinating agent containing IF5 and at least one member selected from the group consisting of acids, bases, salts and additives.

Abstract: The present invention provides a process for preparing a perfluoroalkyl bromide characterized by reacting a perfluoroalkyl iodide represented by the formula C.sub.n F.sub.2n+1 I wherein n is an integer of 6 to 10 with bromine in a light-transmitting reactor with exposure to light and heating at 120.degree. to 180.degree. C. while simultaneously removing IBr resulting as a by-product by separation of a layer.

Abstract: A 2-nitroimidazole compound of the formula: ##STR1## wherein R.sub.f is a fluorine-containing organic group which has at least one fluorine atom on a carbon atom which bonds to the nitrogen atom of the imidazole ring or a carbon atom which bonds to said carbon atom and a radiosensitizer comprising said nitroimidazole derivative.

Abstract: A fluorine-containing platinum complex having anti-tumor activity of the formula: ##STR1## wherein R.sub.1 is a fluorine atom or a trifluoromethyl group,R.sub.2 is a fluorine atom, a hydrogen atom or a lower alkyl group,X is a halogen atom, a group of the formula: --NO.sub.2, or two Xs combined to form a group of the formulae: ##STR2## Y is a hydroxyl group or a halogen atom, and n is 0 or 1,and an anti-tumor composition comprising the same as an active ingredient.

Abstract: A 2-nitroimidazole derivative of the formula: ##STR1## wherein R.sub.f is a group of the following formula (II) or (III):--CH.sub.2 CFXCH.sub.2 OR.sub.1 (II)wherein X is a hydrogen atom or a halogen atom; R.sub.1 is a group of the formula: ##STR2## wherein R.sub.2 is a hydrogen atom, a hydroxyl group, a C.sub.1 -C.sub.3 alkyl group, a C.sub.2 -C.sub.4 acyl group, benzylidene or acetonide; R.sub.3 is a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group; Z is a hydrogen atom, COOY, COOR.sub.3, CONHOY, CONR.sub.4 R.sub.5 (wherein R.sub.4 and R.sub.5 are hydroxyl group-containing C.sub.1 -C.sub.3 alkyl groups or hydrogen atoms; Y is a hydrogen atom or a monovalent metal atom), an amino group, a hydroxyl group or OR.sub.3 ; l is an integer of 1 to 3; o is an integer of 0 to 3; p is an integer of 0 to 2; q is an integer of 0 to 3; m and n are integers of 0 to 4; and 1.ltoreq.m+n.ltoreq.4 or ##STR3## wherein R.sub.3, X and p are the same as defined above; Z' is the same as Z or is OCOOCH.sub.

Abstract: A nitroazole derivative of the formula:NA--R.sub.f (I)wherein NA is 3-nitro-1,2,4-triazol-l-yl and R.sub.f is a fluorine-containing organic group which is useful as a radiosensitizer.

Abstract: A fluorine-containing macrolide compound of the formula: ##STR1## wherein R.sup.1 is hydroxy or --OR (wherein R is C.sub.1 -C.sub.5 alkyl),R.sup.2 is hydrogen or hydroxy, orR.sup.1 and R.sup.2 together form a cyclic residue of the formula: ##STR2## (wherein R' and R" are independently hydrogen or C.sub.1 -C.sub.5 alkyl), ##STR3## when R.sup.4 is hydrogen or C.sub.1 -C.sub.5 alkyl, or R.sup.3 is ##STR4## when R.sup.4 is ##STR5## (wherein Ph is phenyl), R.sup.5 is hydrogen or C.sub.1 -C.sub.5 alkyl, andR.sup.6 is hydrogen or methyland an antimicrobial agent containing the fluorine-containing macrolide compound (I) as an effective component.

Abstract: A novel 5-fluorouridine derivative of the formula: ##STR1## wherein R.sup.1 is a C.sub.1 -C.sub.10 aliphatic carbonyl group, R.sup.2 is a fluorine atom or a C.sub.1 -C.sub.3 aliphatic carbonyloxy group, and x is a halogen atom such as a fluorine, chlorine, bromine and iodine atom, which is useful as an intermediate in the preparation of a 5-fluoro-2'-deoxyuridine derivative which is useful as an anticancer agent.

Abstract: A novel 5-fluorouracil derivative of the formula: ##STR1## wherein R.sup.1 is a fluorine-containing C.sub.1 -C.sub.10 organic group which optionally contains sulfur, oxygen and/or nitrogen. The novel 5-fluorouracil derivative is useful as a carcinostatic substance, which has a high carcinostatic activity but which is less toxicity against digestive tract and causes less autonomic imbalance than other known 5-fluorouracil derivatives.

Abstract: A fluorine-containing 3-oxygenated-.DELTA..sup.3,5 -steroid is prepared in a good yield by fluorinating a steroid with a compound of the formula:RCOOFwherein R is a hydrocarbon group.

Abstract: Monofluorobenzene is prepared in a good yield by reacting cyclopentadiene or its dimer of the formula: ##STR1## with fluorohalomethane of the formula:CHFX.sub.2wherein Xs are, same or different, halogen atoms in the presence of a phase transfer catalyst and an acid acceptor.