Patents by Inventor Kazuhito Noguchi
Kazuhito Noguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7504432Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); [in which A signifies a group expressed by a formula (a0) or (b0); Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X? signifies an anion].Type: GrantFiled: January 3, 2007Date of Patent: March 17, 2009Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
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Patent number: 7452908Abstract: This invention relates to compounds which are represented by the general formula [I] [in which A stands for a group of the following formula [ao] or [b0] Ar1, Ar2 and Ar3 stand for optionally substituted phenyl; k stands for 0 or 1; m, n and s stand for 0, 1 or 2; R1 stands for hydrogen or optionally substituted lower alkyl; R2, R3, R4 and R5 either stand for hydrogen or optionally substituted lower alkyl, or R2 and R3, or R4 and R5 together stand for trimethylene and the like; R60 stands for hydrogen, alkyl, or the like; R61 and R71 either stand for alkyl and the like, or together stand for trimethylene and the like; X stands for carbonyl or methylene; Y stands for nitrogen or methine; and Q? stands for anion], and the like. The compounds of the invention exhibit selective antagonism to muscarinic M3 receptors, and therefore are useful as safe and effective agents showing little side effect, for treating diseases of the respiratory, urinary and digestive systems.Type: GrantFiled: May 5, 2004Date of Patent: November 18, 2008Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Yufu Sagara, Minaho Uchiyama, Akira Naya, Toshifumi Kimura, Tomoshige Numazawa, Toru Fujikawa, Norikazu Otake, Kazuhito Noguchi
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Patent number: 7381032Abstract: In a hermetic compressor in a freezing refrigerating system or an air-conditioning system such as a refrigerator or a showcase, a construction is disclosed for intending to provide a low-noise hermetic compressor by effectively attenuating a pressure pulsation having occurred in a compression chamber with a suction muffler. By this construction, since a muffler cover 20 has a planar simple shape, the deformation upon molding becomes little and it can come into fully close contact with a muffler main body 19. Therefore, the pressure pulsation hardly leaks through the connecting portion between the muffler main body 19 and the muffler cover 20. The full silencing effect that the suction muffler 18 has is obtained and thereby noise can be reduced more effectively.Type: GrantFiled: November 26, 2001Date of Patent: June 3, 2008Assignee: Matsushita Refrigeration CompanyInventors: Masahiko Osaka, Hidetoshi Nishihara, Toshihiko Ota, Akihiko Kubota, Manabu Motegi, Hiroki Awashima, Takeshi Kojima, Kazuhito Noguchi, Ichiro Kita, Masahiro Kakutani
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Patent number: 7244108Abstract: This invention relates to a hermetic compressor used on a refrigerant cycle such as a refrigerator, and discloses a low noise compressor designed to attenuate a resonance sound in a compression chamber and intake pressure pulsing more operatively at a position adjacent to their sources, which intake pressure pulsing occurs at an intake valve port. In the compressor, a resonance space 38 is provided adjacent to the intake valve port 29 that is closer in distance to a noise source. As a result, noise can be reduced more operatively than muffling functions of an intake muffler 31 do. In addition, although acoustic characteristics of the intake muffler 31 amplify noises having specific frequencies, such noises can be attenuated before being amplified.Type: GrantFiled: November 26, 2001Date of Patent: July 17, 2007Assignee: Matsushita Refrigeration CompanyInventors: Akihiko Kubota, Hidetoshi Nishihara, Masahiko Osaka, Toshihiko Ota, Hiroki Awashima, Manabu Motegi, Kazuhito Noguchi, Takeshi Kojima, Masahiro Kakutani
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Publication number: 20070129397Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); [in which A signifies a group expressed by a formula (a0) or (b0); Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X?signifies an anion].Type: ApplicationFiled: January 3, 2007Publication date: June 7, 2007Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
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Patent number: 7192969Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); [in which A signifies a group expressed by a formula (a0) or (b0); Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X? signifies an anion].Type: GrantFiled: November 9, 2004Date of Patent: March 20, 2007Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
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Patent number: 7021425Abstract: A sealed electric compressor for use in, for example, an electric refrigerator, generates a little noise and can feed any moving part of its compressing element with refrigerator lubricant. An oil pickup tube is joined by insertion to the lowermost end of a crank shaft and includes a first centrifugal pumping portion and a second centrifugal pumping portion provided continuously and arranged at a smaller angle than that of the first centrifugal pumping portion. The second centrifugal pumping portion arranged at a smaller angle can spin in a pool of the refrigerator lubricant.Type: GrantFiled: May 30, 2001Date of Patent: April 4, 2006Assignee: Matsushita Refrigeration CompanyInventors: Kazuhito Noguchi, Akihiko Kubota, Masahiko Osaka, Manabu Motegi, Hidetoshi Nishihara
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Patent number: 6957951Abstract: In a hermetic compressor for use on an air-conditioning unit as well as a refrigerating unit such as a refrigerator and a showcase, there is disclosed a constitution designed to provide a silently operated hermetic compressor that has an intake muffler readily assembled thereon. The hermetic compressor including a substantially disk-like elastic member disposed between the intake muffler at an outlet thereof and a cylinder head is provided, in which an outlet orifice of the intake muffler constantly remains pressed against an intake valve port through a gasket.Type: GrantFiled: December 20, 2001Date of Patent: October 25, 2005Assignee: Matsushita Refrigeration CompanyInventors: Toshihiko Ota, Hidetoshi Nishihara, Akihiko Kubota, Masahiko Osaka, Manabu Motegi, Kazuhito Noguchi, Takeshi Kojima
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Publication number: 20050100456Abstract: In a hermetic compressor in a freezing refrigerating system or an air-conditioning system such as a refrigerator or a showcase, a construction is disclosed for intending to provide a low-noise hermetic compressor by effectively attenuating a pressure pulsation having occurred in a compression chamber with a suction muffler. By this construction, since a muffler cover 20 has a planar simple shape, the deformation upon molding becomes little and it can come into fully close contact with a muffler main body 19. Therefore, the pressure pulsation hardly leaks through the connecting portion between the muffler main body 19 and the muffler cover 20. The full silencing effect that the suction muffler 18 has is obtained and thereby noise can be reduced more effectively.Type: ApplicationFiled: November 26, 2001Publication date: May 12, 2005Inventors: Masahiko Osaka, Hidetoshi Nishihara, Toshihiko Ota, Akihiko Kubota, Manabu Motegi, Hiroki Awashima, Takeshi Kojima, Kazuhito Noguchi, Ichiro Kita, Masahiro Kakutani
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Publication number: 20050065211Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); [in which A signifies a group expressed by a formula (a0) or (b0); Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X? signifies an anion].Type: ApplicationFiled: November 9, 2004Publication date: March 24, 2005Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
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Patent number: 6846835Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); [in which A signifies a group expressed by a formula (a0) or (b0); Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X? signifies an anion].Type: GrantFiled: July 10, 2001Date of Patent: January 25, 2005Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
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Patent number: 6809108Abstract: This invention relates to compounds which are represented by the general formula [I] [in which A stands for a group of the following formula [a0] or [b0] Ar1, Ar2 and Ar3 stand for optionally substituted phenyl; k stands for 0 or 1; m, n and a stand for 0, 1 or 2; R1 stands for hydrogen or optionally substituted lower alkyl; R2, R3, R4 and R5 either stand for hydrogen or optionally substituted lower alkyl, or R2 and R3, or R4 and R5 together stand for trimethylene and the like; R60 stands for hydrogen, alkyl, or the like; R61 and R71 either stand for alkyl and the like, or together stand for trimethylene and the like; X stands for carbonyl or methylene; Y stands for nitrogen or methine; and Q− stands for anion], and the like.Type: GrantFiled: March 26, 2002Date of Patent: October 26, 2004Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Yufu Sagara, Minaho Uchiyama, Akira Naya, Toshifumi Kimura, Tomoshige Numazawa, Toru Fujikawa, Norikazu Otake, Kazuhito Noguchi
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Publication number: 20040204369Abstract: This invention relates to compounds which are represented by the general formula [I] 1Type: ApplicationFiled: May 5, 2004Publication date: October 14, 2004Inventors: Yufu Sagara, Minaho Uchiyama, Akira Naya, Toshifumi Kimura, Tomoshige Numazawa, Toru Fujikawa, Norikazu Otake, Kazuhito Noguchi
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Publication number: 20040052653Abstract: This invention relates to a hermetic compressor used on a refrigerant cycle such as a refrigerator, and discloses a low noise compressor designed to attenuate a resonance sound in a compression chamber and intake pressure pulsing more operatively at a position adjacent to their sources, which intake pressure pulsing occurs at an intake valve port. In the compressor, a resonance space 38 is provided adjacent to the intake valve port 29 that is closer in distance to a noise source. As a result, noise can be reduced more operatively than muffling functions of an intake muffler 31 do. In addition, although acoustic characteristics of the intake muffler 31 amplify noises having specific frequencies, such noises can be attenuated before being amplified.Type: ApplicationFiled: September 25, 2003Publication date: March 18, 2004Inventors: Akihiko Kubota, Hidetoshi Nishihara, Masahiko Osaka, Hiroki Awashima, Manabu Motegi, Manabu Motegi, Kazuhito Noguchi, Takeshi Kojima, Masahiro Kakutani
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Patent number: 6699880Abstract: This invention relates to the compounds represented by the general formula [I], [in which A—D signify optionally substituted methine group(s) or nitrogen atom; E signifies oxygen or sulfur atom; signify optionally substituted mono- or bi-cyclic aliphatic nitrogen-containing heterocyclic group(s); R1 signifies lower alkenyl, lower alkynyl, cyclo(lower alkyl), lower alkanoyl, lower alkoxycarbonyl, optionally substituted lower alkyl and the like; and R2 signifies lower alkyl].Type: GrantFiled: April 15, 2002Date of Patent: March 2, 2004Assignee: Banyu Pharmaceutical Co., Ltd.Inventors: Takeru Yamakawa, Makoto Ando, Seita Koito, Kenji Ohwaki, Toshifumi Kimura, Toshihiko Saeki, Mitsuru Miyaji, Yuki Iwahori, Toru Fujikawa, Norikazu Otake, Kazuhito Noguchi
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Publication number: 20040037712Abstract: In a hermetic compressor for use on an air-conditioning unit as well as a refrigerating unit such as a refrigerator and a showcase, there is disclosed a constitution designed to provide a silently operated hermetic compressor that has an intake muffler readily assembled thereon. The hermetic compressor including a substantially disk-like elastic member disposed between the intake muffler at an outlet thereof and a cylinder head is provided, in which an outlet orifice of the intake muffler constantly remains pressed against an intake valve port through a gasket.Type: ApplicationFiled: June 5, 2003Publication date: February 26, 2004Inventors: Toshihiko Ota, Hidetoshi Nishihara, Akihiko Kubota, Masahiko Osaka, Manabu Motegi, Kazuhito Noguchi, Takeshi Kojima
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Publication number: 20030191316Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); 1Type: ApplicationFiled: January 10, 2003Publication date: October 9, 2003Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
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Publication number: 20030161741Abstract: A sealed electric compressor for use in, for example, an electric refrigerator, generates a little noise and can feed any moving part of its compressing element with refrigerator lubricant. An oil pickup tube is joined by insertion to the lowermost end of a crank shaft and includes a first centrifugal pumping portion and a second centrifugal pumping portion provided continuously and arranged at a smaller angle than that of the first centrifugal pumping portion. The second centrifugal pumping portion arranged at a smaller angle can spin in a pool of the refrigerator lubricant.Type: ApplicationFiled: March 27, 2003Publication date: August 28, 2003Inventors: Kazuhito Noguchi, Akihiko Kubota, Masahiko Osaka, Manabu Motegi, Hidetoshi Nishihara
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Patent number: 6276906Abstract: A hermetic motor compressor includes a generally spherical casing having a generally spherical side wall and a first downwardly curved bottom wall, an integrated structure accommodated in said casing and having a compression section and a drive section integrally formed with each other, and a plurality of supporting units for elastically supporting the integrated structure. A plurality of legs are secured to the first downwardly curved bottom wall, and each of them is of the same shape as the downwardly curved bottom wall.Type: GrantFiled: November 18, 1999Date of Patent: August 21, 2001Assignee: Matsushita Refrigeration CompanyInventor: Kazuhito Noguchi
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Patent number: 6130232Abstract: This invention provides substituted heteroaromatic ring derivatives which are represented by a general formula [I] below: ##STR1## [in the formula, R.sup.1 and R.sup.2 may be same or different and each signifies hydrogen, halogen or lower alkyl; R.sup.3 signifies C.sub.3 -C.sub.6 cycloalkyl or cycloalkenyl; R.sup.4 signifies a heteroaromatic ring group which may be condensed with a benzene ring and which has 1 or 2 hetero atoms selected from a group consisting of nitrogen, oxygen and sulfur atoms (said heteroaromatic ring group being optionally substituted with lower alkyl, halogen, lower alkoxy, amino or hydroxymethyl); and X stands for O or NH]or their pharmaceutically acceptable salts.The substituted heteroaromatic ring derivatives of the present invention have selective M.sub.Type: GrantFiled: April 9, 1998Date of Patent: October 10, 2000Assignee: Banyu Pharmaceutical CoaltdInventors: Toshiaki Mase, Morihiro Mitsuya, Kensuke Kobayashi, Kazuhito Noguchi