Patents by Inventor Kazuhito Sugimura

Kazuhito Sugimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF USING A NOD2/CARD15 HAPLOTYPE TO DIAGNOSE CROHN'S DISEASE
    Publication number: 20110117552
    Abstract: The present invention provides a method of diagnosing or predicting susceptibility to Crohn's disease in an individual by determining the presence or absence in the individual of a disease-predisposing haplotype containing a JW1 variant allele at the NOD2/CARD15 locus, where the presence of the disease-predisposing haplotype is diagnostic of or predictive of susceptibility to Crohn's disease.
    Type: Application
    Filed: October 11, 2010
    Publication date: May 19, 2011
    Applicant: Cedars-Sinai Medical Center
    Inventors: Kent D. Taylor, Jerome I. Rotter, Huiying Yang, Kazuhito Sugimura, Stephan R. Targan
  • Methods of using a NOD2/CARD15 haplotype to diagnose Crohn's disease
    Publication number: 20040076960
    Abstract: The present invention provides a method of diagnosing or predicting susceptibility to Crohn's disease in an individual by determining the presence or absence in the individual of a disease-predisposing haplotype containing a JW1 variant allele at the NOD2/CARD15 locus, where the presence of the disease-predisposing haplotype is diagnostic of or predictive of susceptibility to Crohn's disease.
    Type: Application
    Filed: October 18, 2002
    Publication date: April 22, 2004
    Inventors: Kent D. Taylor, Jerome I. Rotter, Huiying Yang, Kazuhito Sugimura, Stephan R. Targan
  • Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
    Publication number: 20040053263
    Abstract: The present invention provides a method of diagnosing or predicting susceptibility to a clinical subtype of Crohn's disease characterized by fibrostenosing disease by determining the presence or absence in an individual of a fibrostenosis-predisposing allele linked to a NOD2/CARD15 locus, where the presence of the fibrostenosis-predisposing allele is diagnostic of or predictive of susceptibility to the clinical subtype of Crohn's disease characterized by fibrostenosing disease. In a method of the invention, the clinical subtype of Crohn's disease can be, for example, characterized by fibrostenosing disease independent of small bowel involvement.
    Type: Application
    Filed: January 30, 2003
    Publication date: March 18, 2004
    Inventors: Maria T. Abreu, Kent D. Taylor, Jerome I. Rotter, Huiying Yang, Kazuhito Sugimura, Stephan R. Targan