Patents by Inventor Kazuki Fukushima
Kazuki Fukushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130011457Abstract: Biodegradable cationic block copolymers are disclosed, comprising a hydrophilic block comprising first repeat units derived from a first cyclic carbonyl monomer by ring-opening polymerization, wherein more than 0% of the first repeat units comprise a side chain moiety comprising a quaternary amine group; a hydrophobic block comprising second repeat units derived from a second cyclic carbonyl monomer by ring-opening polymerization; an optional endcap group; and a chain fragment derived from an initiator for the ring opening polymerization. The cationic block copolymers form aqueous micelle mixtures suitable for antimicrobial applications.Type: ApplicationFiled: September 14, 2012Publication date: January 10, 2013Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: James Hedrick, Kazuki Fukushima, Yi Yan Yang
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Publication number: 20120322949Abstract: Block copolymers include hydrophobic and hydrophilic blocks having repeating units derived from ring opening polymerization of one or more cyclic carbonate monomers. The carbonate monomers are independently selected from compounds of formula (II): wherein each Q? and Qa group independently represents a hydrogen, an alkyl group, a halide, a carboxy group, an ester group, an amide group, an aryl group, an alkoxy group, or a foregoing Q? or Qa group substituted with a carboxy group or an ester group, at least one Q? and Qa group includes an ester group; each Y independently represents O, S, NH, or NQ?; n is an integer from 0 to 6, wherein when n is 0, carbons labeled 4 and 6 are linked together by a single bond; each Q? group independently represents an alkyl group, an aryl group, or a foregoing Q? group substituted with a carboxy group, or an ester group.Type: ApplicationFiled: July 6, 2012Publication date: December 20, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Kazuki Fukushima, James L. Hedrick, Sung-Ho Kim, Robert M. Waymouth
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Publication number: 20120297905Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: ApplicationFiled: August 9, 2012Publication date: November 29, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Publication number: 20120301672Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: ApplicationFiled: August 9, 2012Publication date: November 29, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Patent number: 8304490Abstract: It is an object of the present invention to provide polylactic acid containing a stereocomplex crystal and having excellent moldability, a high molecular weight, high crystallinity and a high melting point and a process for manufacturing the same. It is another object of the present invention to provide a composition comprising the polylactic acid and a molded product of the polylactic acid. The present invention is characterized from polylactic acid having a weight average molecular weight of 80,000 to 500,000 and a melting peak at 195° C. or higher which accounts for 80% or more of the total of melting peaks in the temperature elevation step when measured by a differential scanning calorimeter (DSC) and a process for manufacturing the same.Type: GrantFiled: July 20, 2005Date of Patent: November 6, 2012Assignees: Teijin Limited, Musashino Chemical Laboratory, Ltd, Mutual CorporationInventors: Yoshiharu Kimura, Zhen Tang, Kazuki Fukushima, Kiyotsuna Toyohara, Ryuji Nonokawa, Yasuhito Maeda, Masayuki Takada, Yuka Komazawa, Tsuyoshi Aoki
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Publication number: 20120251608Abstract: A cationic star polymer is disclosed of the general formula (1): I??P?]w???(1), wherein w? is a positive number greater than or equal to 3, I? is a dendritic polyester core covalently linked to w? independent peripheral linear cationic polymer chains P?. Each of the chains P? comprises a cationic repeat unit comprising i) a backbone functional group selected from the group consisting of aliphatic carbonates, aliphatic esters, aliphatic carbamates, aliphatic ureas, aliphatic thiocarbamates, aliphatic dithiocarbonates, and combinations thereof, and ii) a side chain comprising a quaternary amine group. The quaternary amine group comprises a divalent methylene group directly covalently linked to i) a positive charged nitrogen and ii) an aromatic ring.Type: ApplicationFiled: December 21, 2011Publication date: October 4, 2012Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel Joseph Coady, Amanda Catherine Engler, Kazuki Fukushima, James Lupton Hedrick, Jeremy Pang Kern Tan, Yi Yan Yang
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Publication number: 20120251607Abstract: A composition of matter comprises a cationic polymer comprising a polycarbonate chain fragment, the polycarbonate chain fragment comprising a repeat unit comprising a side chain moiety containing a quaternary amine group; and a non-charged polymer comprising a polyester chain segment and a poly(alkylene oxide) chain segment; wherein i) the cationic polymer and the non-charged polymer are amphiphilic and biocompatible, ii) the cationic polymer and the non-charged polymer form a mixed complex by non-covalent interactions in water, and iii) the mixed complex is a more effective antimicrobial agent against at least a Gram-negative microbe compared to the cationic polymer and the non-charged polymer alone when tested using otherwise identical conditions.Type: ApplicationFiled: March 31, 2011Publication date: October 4, 2012Inventors: Daniel J. Coady, Kazuki Fukushima, James L. Hedrick, Yi Yan Yang
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Publication number: 20120245218Abstract: A composition comprises a surface modified nanoparticle comprising a core comprising a material selected from the group consisting of organic materials, organometallic materials, inorganic materials, metals, metal oxides, and combinations thereof; and a surface branch covalently linked to the core having the general formula (3):Type: ApplicationFiled: June 5, 2012Publication date: September 27, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Kazuki Fukushima, James L. Hedrick, Alshakim Nelson, Daniel P. Sanders
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Patent number: 8263715Abstract: A block copolymer includes a hydrophobic block and a hydrophilic block, wherein the hydrophobic block and the hydrophilic block include repeating units derived from ring opening polymerization of one or more cyclic carbonate monomers. The one or more cyclic carbonate monomers are independently selected from compounds of the general formula (II): wherein each Q? and Qa group independently represents a hydrogen, an alkyl group, a halide, a carboxy group, an ester group, an amide group, an aryl group, an alkoxy group, or a foregoing Q? or Qa group substituted with a carboxy group or an ester group, at least one Q? and Qa group includes an ester group; each Y independently represents O, S, NH, or NQ?; n is an integer from 0 to 6, wherein when n is 0, carbons labeled 4 and 6 are linked together by a single bond; each Q? group independently represents an alkyl group, an aryl group, or a foregoing Q? group substituted with a carboxy group, or an ester group.Type: GrantFiled: August 28, 2009Date of Patent: September 11, 2012Assignees: International Business Machines Corporation, The Board of Trustees of the Leland Stanford Junior UniversityInventors: Kazuki Fukushima, James L. Hedrick, Sung-Ho Kim, Robert M. Waymouth
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Publication number: 20120223270Abstract: A method comprises forming a reaction mixture comprising a terephthalate polyester, a glycol comprising 2 to 5 carbons, and an amidine organocatalyst; and heating the reaction mixture at a temperature of about 120° C. or more to depolymerize the terephthalate polyester, thereby forming a terephthalate reaction product comprising a monomeric dihydroxy terephthalate diester; wherein the terephthalate reaction product contains terephthalate oligomers in an amount less than the amount of terephthalate oligomers that would result from i) substituting the amidine organocatalyst with an equimolar amount of a guanidine catalyst and ii) depolymerizing the terephthalate polyester under otherwise identical reaction conditions.Type: ApplicationFiled: March 4, 2011Publication date: September 6, 2012Applicants: KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Abdullah M. Alabdulrahman, Hamid A. Almegren, Fares D. Alsewailem, Phillip Joe Brock, Daniel Joseph Coady, Kazuki Fukushima, James Lupton Hedrick, Hans Werner Horn, Julia Elizabeth Rice
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Patent number: 8226985Abstract: A composition comprises a surface modified nanoparticle comprising a core comprising a material selected from the group consisting of organic materials, organometallic materials, inorganic materials, metals, metal oxides, and combinations thereof; and a surface branch covalently linked to the core having the general formula (3):Type: GrantFiled: January 28, 2010Date of Patent: July 24, 2012Assignee: International Business Machines CorporationInventors: Kazuki Fukushima, James Lupton Hedrick, Alshakim Nelson, Daniel Paul Sanders
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Publication number: 20120082944Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: ApplicationFiled: September 30, 2010Publication date: April 5, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Publication number: 20120046437Abstract: A salt catalyst comprises an ionic complex of i) a nitrogen base comprising one or more guanidine and/or amidine functional groups, and ii) an oxoacid comprising one or more active acid groups, the active acid groups independently comprising a carbonyl group (C?O), sulfoxide group (S?O), and/or a phosphonyl group (P?O) bonded to one or more active hydroxy groups; wherein a ratio of moles of the active hydroxy groups to moles of the guanidine and/or amidine functional groups is greater than 0 and less than 2.0. The salt catalysts are capable of catalyzing ring opening polymerization of cyclic carbonyl compounds.Type: ApplicationFiled: August 19, 2010Publication date: February 23, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel Joseph Coady, Kazuki Fukushima, James Lupton Hedrick, Hans Werner Horn, Julia Elizabeth Rice
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Publication number: 20110182996Abstract: A composition comprises a surface modified nanoparticle comprising a core comprising a material selected from the group consisting of organic materials, organometallic materials, inorganic materials, metals, metal oxides, and combinations thereof; and a surface branch covalently linked to the core having the general formula (3):Type: ApplicationFiled: January 28, 2010Publication date: July 28, 2011Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Kazuki Fukushima, James L. Hedrick, Alshakim Nelson, Daniel P. Sanders
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Publication number: 20110150977Abstract: Biodegradable cationic block copolymers are disclosed, comprising a hydrophilic block comprising first repeat units derived from a first cyclic carbonyl monomer by ring-opening polymerization, wherein more than 0% of the first repeat units comprise a side chain moiety comprising a quaternary amine group; a hydrophobic block comprising second repeat units derived from a second cyclic carbonyl monomer by ring-opening polymerization; an optional endcap group; and a chain fragment derived from an initiator for the ring opening polymerization. The cationic block copolymers form aqueous micelle mixtures suitable for antimicrobial applications.Type: ApplicationFiled: December 23, 2009Publication date: June 23, 2011Inventors: James HEDRICK, Kazuki FUKUSHIMA, Yi Yan YANG
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Publication number: 20110151566Abstract: A biodegradable cationic polymer is disclosed, comprising first repeat units derived from a first cyclic carbonyl monomer by ring-opening polymerization, wherein more than 0% of the first repeat units comprise a side chain moiety comprising a quaternary amine group; a subunit derived from a monomeric diol initiator for the ring-opening polymerization; and an optional endcap group. The biodegradable cationic polymers have low cytotoxicity and form complexes with biologically active materials useful in gene therapeutics and drug delivery.Type: ApplicationFiled: December 23, 2009Publication date: June 23, 2011Inventors: James HEDRICK, Kazuki FUKUSHIMA, Yi Yan YANG
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Publication number: 20110054064Abstract: A block copolymer includes a hydrophobic block and a hydrophilic block, wherein the hydrophobic block and the hydrophilic block include repeating units derived from ring opening polymerization of one or more cyclic carbonate monomers. The one or more cyclic carbonate monomers are independently selected from compounds of the general formula (II): wherein each Q? and Qa group independently represents a hydrogen, an alkyl group, a halide, a carboxy group, an ester group, an amide group, an aryl group, an alkoxy group, or a foregoing Q? or Qa group substituted with a carboxy group or an ester group, at least one Q? and Qa group includes an ester group; each Y independently represents O, S, NH, or NQ?; n is an integer from 0 to 6, wherein when n is 0, carbons labeled 4 and 6 are linked together by a single bond; each Q? group independently represents an alkyl group, an aryl group, or a foregoing Q? group substituted with a carboxy group, or an ester group.Type: ApplicationFiled: August 28, 2009Publication date: March 3, 2011Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Kazuki Fukushima, James L. Hedrick, Sung-Ho Kim, Robert M. Waymouth
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Publication number: 20080039579Abstract: It is an object of the present invention to provide polylactic acid containing a stereocomplex crystal and having excellent moldability, a high molecular weight, high crystallinity and a high melting point and a process for manufacturing the same. It is another object of the present invention to provide a composition comprising the polylactic acid and a molded product of the polylactic acid. The present invention is characterized from polylactic acid having a weight average molecular weight of 80,000 to 500,000 and a melting peak at 195° C. or higher which accounts for 80% or more of the total of melting peaks in the temperature elevation step when measured by a differential scanning calorimeter (DSC) and a process for manufacturing the same.Type: ApplicationFiled: July 20, 2005Publication date: February 14, 2008Applicants: Teijin Limited, Musashino Chemical Laboratory, Ltd., Mutual Corporation, Yoshiharu KimuraInventors: Yoshiharu Kimura, Zhen Tang, Kazuki Fukushima, Kiyotsuna Toyohara, Ryuji Nonokawa, Yasuhito Maeda, Masayuki Takada, Yuka Komazawa, Tsuyoshi Aoki