Abstract: A control device that is mounted in a second vehicle which a first vehicle having a following travel function is detachably connected to or loaded on is provided. The control device includes a control unit configured to perform: detecting another vehicle that is within a predetermined range from the second vehicle in a state in which the second vehicle has the first vehicle connected thereto or loaded thereon and of which some or all of a scheduled travel route is the same as some or all of a scheduled travel route of the first vehicle after the first vehicle has been disconnected from the second vehicle; and transmitting following instruction information to the first vehicle and disconnecting the first vehicle from the second vehicle such that the first vehicle travels with the detected other vehicle as a preceding vehicle by the following travel function.

Abstract: The subject matter disclosed herein is generally directed to modulation of genes and pathways that drive differentiation of LGR5+ stem cells. The methods and compositions can be used to treat diseases associated with aberrant epithelial barrier function. Using novel screening methods Applicants have identified compounds that increase Paneth cell differentiation. The compounds can be used to treat diseases associated with stem cell differentiation.

Abstract: A triazine compound represented by formula (1) is provided. In the formula (1), A and B each independently represent an aryl group having 6 to 20 carbon atoms; L represents a phenyl group or a naphthyl group; n is 0 or 1; and C represents any one of groups X, Y, and Z below, wherein Ar1 and Ar2 each independently represent an aromatic hydrocarbon group or a pyridyl group.

Abstract: The subject matter disclosed herein is generally directed to modulation of genes and pathways that drive differentiation of LGR5+ stem cells. The methods and compositions can be used to treat diseases associated with aberrant epithelial barrier function.

Abstract: An object of the present invention is to provide a cyclic azine compound exhibiting both excellent driving voltage characteristics and excellent current efficiency characteristics. The desired cyclic azine compound has a specific structure represented by formula (1).

Abstract: Provided is a toilet bowl comprising an upper forming body having an upper surface part that forms an upper surface of the toilet bowl in an installed state; and a lower forming body having an inner wall part joined to an inner edge part of the upper surface part, and an outer wall part joined to an outer edge part of the upper surface part. A space part is formed between the inner wall part and the outer wall part. A dimension in an up-down direction from a lower end of the space part to an upper surface of the inner wall part is larger than a dimension in the up-down direction from an upper end of the space part to the upper surface of the inner wall part.

Abstract: Leucine-rich repeat-containing G-protein coupled receptor 5-positive (LGR5+) intestinal cells are contacted with an inhibitor of exportin 1 (XPO1), thereby producing functionally differentiated intestinal cells. The LGR5+ cells can also be contacted with a Wnt agonist. The LGR5+ cells can also be contacted with a Notch inhibitor.